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Algae-Based DHA vs. Flax

Everyone should consider taking plant-based (yeast- or algae-derived) long chain omega-3 fatty acid (DHA/EPA) supplements.

October 7, 2010 |
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Supplementary Info

Algae-Based DHA vs. Flax, 5.0 out of 5 based on 3 ratings

Sources Cited

Acknowledgements

Transcript

Because even distilled fish oil has been found to contain toxic industrial pollutants, the safest source is algae or yeast derived EPA/DHA (our bodies can retroconvert DHA into EPA and vice-versa). See some of my reasoning here. My recommendation is to ideally get 250 to 500 mg a day

Very few people in this country eat the recommended amount of fish, and those who do probably… glow in the dark and are so flame retardant they can probably broil their fish fillet over an open fire with their bare hands.

There are at least six sources of micro-algae based DHA currently on the market. There’s Deva. Omega-zen capsules, omega-zen liquid, Dr. Fuhrman’s brand, Spectrum makes one, and V-Pure brand. Udo’s oil makes one too.

This is not even negotiable for all pregnant and breastfeeding women. Just within the last year, mothers given DHA supplements had infants with significantly better vision at two months, significantly better problem solving at 9 months, and were significantly smarter at 4 years old—it bumped their IQ as well.

We can make DHA ourselves from the shorter chain omega-3’s in flaxseeds, but probably not enough for optimum health. Still, flax is amazing stuff.

To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring watch the above video. This is just an approximation of the audio contributed by Dianne Moore.

To help out on the site please email volunteer@nutritionfacts.org

Dr. Michael Greger

Doctor's Note

Please feel free to post any ask-the-doctor type questions here in the comments section and I’d be happy to try to answer them. And check out the other videos on omega-3 fatty acids. Also, there are 1,449 other subjects covered in the rest of my videos--please feel free to explore them as well!

  • http://nutritionfacts.org/members/mgreger/ Michael Greger M.D.

    Please feel free to post any ask-the-doctor type questions here in the comments section and I’d be happy to try to answer them. And check out the other videos on omega-3 fatty acids. Also, there are 1,449 other subjects covered in the rest of my videos–please feel free to explore them as well!

    • http://nutritionfacts.org/members/aguccionesbcglobal-net/ aguccione@sbcglobal.net

      Hi Dr. Greger, This video clip seems to have been clipped short of it’s conclusion.

  • http://nutritionfacts.org/members/cs/ cs

    I’m writing with a question concerning omega-3 fatty acids. You recommend algae- or yeast-derived DHA supplements, as fish oil often has toxins. You also warn that blue-green algae, chlorella and spiraling (all algaes, i think) have toxins in them that might contribute to ALS.

    Are algae-derived DHA supplements based on an algae that doesn’t carry the risks that blue-green algae, chlorella and spiraling do? How does one distinguish? Thanks.

    • http://nutritionfacts.org/members/becochic/ becochic

      Yes, I am wondering this, too. I hope he replies.

    • http://nutritionfacts.org/members/mgreger/ Michael Greger M.D.

      All the algae-oil omega-3 supplements currently on the market are made from golden algae that don’t create the toxins that can be found in blue-green algae (such as spirulina, detailed here: http://nutritionfacts.org/topics/blue-green-algae. Thanks for the question cs and becochic–sorry if you were confused.

  • http://nutritionfacts.org/members/LanceStrish/ Lance Strish

    I am curious about the toxicity/pathogenic activity of algae re: brain health too vs omega-3.
    -
    Also what do you make of this?: ‘Tumors under the skin

    The researchers studied the effect of PIFA’s in mice and human cells. The mice studied had tumors under the skin. Under normal conditions, the tumors would decrease in size following the administration of chemotherapy. In the study, after administering the fatty acids to the mice, the tumors were found to be insensitive to chemotherapy. The fatty acids were isolated from the medium in which chemotherapy exposed stem cells were grown. But also stem cells in the blood of patients produce the fatty acids that desensitize tumors to chemotherapy.

    The fatty acids are also found in commercially-produced fish oil supplements containing omega-3 and omega-6 fatty acids as well as in some algae extracts.’

    I’ve always heard omega-3 fish oil increases telomerase.
    Sciencedaily http://is.gd/8gJ6gq

    • http://nutritionfacts.org/members/LanceStrish/ Lance Strish

      And what to make of this:
      http://perfecthealthdiet.com/?p=3390
      “The papers discussed in Friday’s post about a major angiogenesis pathway stimulated by oxidized DHA (Omega-3s, Angiogenesis and Cancer: Part II, April 29, 2011) may not seem important to many readers. But to cancer researchers and pharmaceutical companies, this is blockbuster work.

      Many foods affect angiogenesis. In fact, cancer studies have identified dozens of plant foods, from garlic to tomatoes to leeks, that possess anti-angiogenic properties.

      However, foods can also promote angiogenesis. Let’s stick to the oxidized DHA pathway and see if there’s evidence that foods drive it.”

  • http://nutritionfacts.org/members/ScottBeavers/ Scott Beavers

    Dr. Greger, do you recommend a particular brand based on dosage and/or quantity of EPAs and DHAs?

    • http://nutritionfacts.org/members/mgreger/ Michael Greger M.D.

      Most of the microalgae-based long chain omega 3′s are source from the same company (Martek) and jsut sold under different brand names so I’d recommend buying whichever’s cheapest! In terms of how much, check out my recommendations here: http://nutritionfacts.org/?p=4060

      • http://nutritionfacts.org/members/ScottBeavers/ Scott Beavers

        Thank you for the reply Dr. Greger. Keep up the great work :)

  • http://nutritionfacts.org/members/aguccionesbcglobal-net/ aguccione@sbcglobal.net

    Dr. Greger, This video clip seems to have been clipped short of it’s conclusion.

  • http://nutritionfacts.org/members/harmony/ Harmony

    Is there any information that can help with glaucoma. The drops are sight saving. what nutritionally can counter any side effects of glaucoma drugs such as cosopt.

    • http://nutritionfacts.org/members/mgreger/ Michael Greger M.D.

      A review of complementary and alternative treatments for glaucoma was published this year (available here). Unfortunately, as you’ll read, the evidence is scarce. In terms of minimizing side-effects, probably the most important thing it to avoid allowing the tip of the dropper to come in contact with your eye or hands or anything (it can become contaminated with common bacteria that can cause eye infections). If you do experience eye redness, pain, or swelling discontinue it and call your doc at once. If I find any new information coming out on effective alternatives I will definitely let you know!

  • http://nutritionfacts.org/members/chrifou/ chrifou

    Hi,

    I use Flora DHA Vegetarian Algae.Each capsul contains 250 mg of DHA sourced from 715 mg of Schizochytrium spp. oil.
    So it’s all DHA, no EPA. Should I get a brand that have DHA and EPA ?

    Thanks for your work. I have all your DVDs and I’m always excited when a new one comes out.

    • http://nutritionfacts.org/members/dsikes/ DSikes

      I have the same question – Dr. Greger’s nutrition guidelines say “DHA and/or EPA” so I assume DHA only algae derived oil is fine but I do wonder…

    • http://nutritionfacts.org/members/dsikes/ DSikes

      Now I’m really curious about this DHA-only algae sourced omega-3 oil vs the EPA. I’ve found a good source of the algae oil (Spectrum prenatal DHA, 60 pills for ~$14 via subscription via Amazon) but it’s only DHA. I’ve read a few places that DHA is great for brain development and thus ideal for prenatal use, but maybe not so useful as EPA for adults. Before I start buying this DHA-only source I’d really like to know the difference between DHA & EPA.

  • http://nutritionfacts.org/members/paulapooh/ PaulaPooh

    http://www.cornucopia.org/2008/01/replacing-mother-infant-formula-report/

    Is there any truth to this report against Martek and it’s safety and clean-ness as a product???
    I really want to go the Algae-based Omega 3′s route, but now I’m completely stuck, scared to ingest this stuff…
    Do have any thoughts??? I’m totally confused now and scared to try this alternative to fish oil.

    So the report said Martek uses a synthetic solvent called hexane- a neurotoxic chemical…is this true???
    And Martek’s Life’sDHA is in some “Organics” and they should NOT be!!!
    Should I be concerned??? Help!!!
    I’m taking flax oil and/or flaxseeds, but I really want to get the DHA/EPA in too!!!
    Please please please read this, thanks a million.

  • Mfrimu

    Hello,

    I came across a blog post from a Ph.D. that is inconsistent with the common conception of these Omega-3 being beneficial.  

    Among some issues: they are immuno-supressive, they oxidate before reaching the bloodstream, and contribute to metastatic cancer.

    What is surprising is at the end of the article, there are about 100 references to scientific studies supporting the view. 

    It seems hard there days to find conclusive evidence in the area of health and diet…

    Mihai 

  • Toxins

    Dr. Greger, how can we be sure that short chain fatty acids are insufficient for our bodies needs?

  • http://www.facebook.com/profile.php?id=670975394 Manuj Ⓥ Chandra

    Is there any test one can take to test Omega-3 levels? What would be the name of this test?

    What are the effects of overdose?

    Are there any symptoms of Omega – 3 deficiency?

    • Toxins

       Omega 3 deficiency is a very rare condition and essentially unkown among healthy populations. All people who consume a healthy plant based diet encounter alot of omega 3 without even knowing it. Kale for example is a good source of omega 3. Men on average need 1.6 grams of omega 3 per day, women need 1.1 grams of omega 3. To check out the levels of omega 3 in your food, visit this website and see the full nutrition profile
      http://nutritiondata.self.com/

  • BPCveg

    I have to respectively disagree with the concluding statement of this video (or at least what Dr. Greger is suggesting at the end). It seems to me that a well planned vegan diet including regular flax consumption should be perfectly sound for most people to meet omega-3 fatty acid needs, without the need for algae oil supplements. 

    According to registered dietician and specialist on vegan nutrition Brenda Davis (copied from her website page ‘Maximizing Essential Fatty Acids in Vegetarian and Vegan Diets’):

     ”Although conversion [of ALA to EPA] is slow and incomplete, it appears to be adequate to meet the needs of most healthy people, if intake of ALA is sufficient.”

    She also goes on to say that:

    “Flaxseeds are by far the richest common source of ALA at 57 percent. One teaspoon of flaxseed oil or one and a half tablespoons of ground flaxseed, plus your usual intake of vegetables, walnuts and other foods provides plenty of omega-3 fatty acids for most people.”

    Of course, Brenda Davis (& other reputable sources such as the dieticians of America and Canada – see 2009 position statement on Vegetarian and Vegan diets) have also indicated that this topic is unsettled and requires further research.

    Future research on this topic may indeed teach us that consuming algae oil is beneficial. Based on the present consensus, however, recommending that everyone take daily algae oil for optimal health seems quite speculative.

    • Toxins

       I also agree with you that omega 3 is easily satisfied with a vegan diet without supplementation

      ALA is not converted effectively to DHA under the condition that one is consuming too many omega 6 fatty acids. Since most whole plant foods contain good rations of omega 6 : omega 3, this is of no concern. The National Academy of Sciences does not recognize EPA and DHA as essential. This means there is enough evidence for them to conclude that we can make enough of it without eating it in its preformed state.

      In addition…

      Do vegetarians have to eat fish for optimal cardiovascular protection?1–3
      Am J Clin Nutr 2009;89(suppl):1S–5S.

      Interest in the cardiovascular protective effects of n–3 (omega-3) fatty acids has continued to evolve during the past 35 y since the original research describing the low cardiovascular event rate in Greenland Inuit was published by Dyerberg et al. Numerous in vitro experiments have shown that n–3 fatty acids may confer this benefit by several mechanisms: they are antiinflammatory, antithrombotic, and antiarrhythmic. The n–3 fatty acids that have received the most attention are those that are derived from a fish source; namely the longer-chain n–3 fatty acids eicosapentaenoic acid (EPA; 20:5n–3) and docosahexaenoic acid (DHA; 22:6n–3). More limited data are available on the cardiovascular effects of n–3 fatty acids derived from plants such as a-linolenic acid (ALA; 18:3n–3). Observational data suggest that diets rich in EPA, DHA, or ALA do reduce cardiovascular events, including myocardial infarction and sudden cardiac death; however, randomized controlled trial data are somewhat less clear. Several recent meta-analyses have suggested that dietary supplementation with EPA and DHA does not provide additive cardiovascular protection beyond standard care, but the heterogeneity of included studies may reduce the validity of their conclusions. No data exist on the potential therapeutic benefit of EPA, DHA, or ALA supplementation on those individuals who already consume a vegetarian diet. Overall, there is insufficient evidence to recommend n–3 fatty acid supplementation for the purposes of cardiovascular protection; however, ongoing studies such as the Alpha Omega Trial may provide further information.

      • BPCveg

        Thanks for adding to my understanding of this topic.

  • Nelson Drake

    is spirulina (herbafresh brand) an algea based DHA omega 3 source? on one of your vids you mentions to stay away from spirulina because of muscle deterioration

  • Nelson Drake

    great! spirulina out, golden algae is in! thank you, this is my favorite site by far

  • Jessiermaher

    Are there any forms of plant based EPA?

    • SimplerMD

      Hi Jessie – I’m a practicing physician helping Dr. Greger with questions such as yours. Here is some info on Nuts and Seeds and EPA:
      Nuts and Seeds
      Some nuts and seeds contain ALA, which the body can convert into EPA, but the process is inefficient, and only a small amount is converted. You can add a handful of ALA-rich nuts and seeds, such as pumpkin seeds, flaxseeds or walnuts to your salad, yogurt or cereal to obtain some of your omega-3 fatty acids. It may be a good idea to take a plant-based omega-3 supplements containing either DHA, EPA or both. Although most omega-3 supplements are made from fish sources, vegetarian supplements are available and are derived mainly from plant sources, such as flaxseed

      here also is a video clip on Flaxseed:
      http://nutritionfacts.org/video/just-the-flax-maam/

  • Jessiermaher

    Also wondering if ALA is used at all in its own right or if the body converts it all to DHA and EPA?

    Love the site, thanks for all your valuable info!

    • Toxins

      your body converts omega 3 from plants (ALA) to DHA and EPA. Fish has
      already preformed DHA so your body does not need to convert it.

      ALA is not converted effectively to DHA under the condition that one
      is consuming too many omega 6 fatty acids. Since most whole plant foods
      contain good ratios of omega 6 : omega 3, this is of no concern unless
      one is eating a lot of nuts other than walnuts, flax seed and chia seed.
      The
      National Academy of Sciences does not recognize EPA and DHA as
      essential. This means there is enough evidence for them to conclude that
      we can make enough of it without eating it in its preformed state.

      In addition…

      Do vegetarians have to eat fish for optimal cardiovascular protection?1–3
      Am J Clin Nutr 2009;89(suppl):1S–5S.

      Interest in the cardiovascular protective effects of n–3 (omega-3)
      fatty acids has continued to evolve during the past 35 y since the
      original research describing the low cardiovascular event rate in
      Greenland Inuit was published by Dyerberg et al. Numerous in vitro
      experiments have shown that n–3 fatty acids may confer this benefit by
      several mechanisms: they are antiinflammatory, antithrombotic, and
      antiarrhythmic. The n–3 fatty acids that have received the most
      attention are those that are derived from a fish source; namely the
      longer-chain n–3 fatty acids eicosapentaenoic acid (EPA; 20:5n–3) and
      docosahexaenoic acid (DHA; 22:6n–3). More limited data are available on
      the cardiovascular effects of n–3 fatty acids derived from plants such
      as a-linolenic acid (ALA; 18:3n–3). Observational data suggest that
      diets rich in EPA, DHA, or ALA do reduce cardiovascular events,
      including myocardial infarction and sudden cardiac death; however,
      randomized controlled trial data are somewhat less clear. Several recent
      meta-analyses have suggested that dietary supplementation with EPA and
      DHA does not provide additive cardiovascular protection beyond standard
      care, but the heterogeneity of included studies may reduce the validity
      of their conclusions. No data exist on the potential therapeutic benefit
      of EPA, DHA, or ALA supplementation on those individuals who already
      consume a vegetarian diet. Overall, there is insufficient evidence to
      recommend n–3 fatty acid supplementation for the purposes of
      cardiovascular protection; however, ongoing studies such as the Alpha
      Omega Trial may provide further information.

  • JP

    Seems like no-one is sure about DHA vs ALA… :

    “If you are getting adequate ALA in your diet from oils and nuts, I am not sure you really need to take an algal DHA supplement…”
    http://www.hsph.harvard.edu/nutritionsource/questions/omega-3/index.html

  • Jen

    Dr. Greger,

    It has been two years since any news on this site regarding vegan sources and/or recommendations of DHA/EPA, or omega 3s in general. I was wondering if there have been any new updates. For one, I know there are now many more sources of DHA/EPA from supplements, my favorite right now being ProAlgen put out by Nordic Naturals.

    Specifically, in this video you recommend vegans (well, everyone) take 200 mg of DHA per day. In my talkings with other doctors, specifically naturopathic ones, that amount, according to them, is woefully low. Most recommend between 2-3 *grams* of combined EPA/DHA per day. I was just wondering if you thought this was unreasonable, or if we all really do need a lot more of these EFAs in our daily mix.

    Thank you :)

    • Dr. Connie Sanchez, ND

      200 mg per day of DHA (long-chain omega-3 fatty acid) has been shown to offer cardio-vascular protection. A 2011 meta-analysis found that 250 mg/d of n-3 LCFA (DHA and EPA) should be considered a minimum target intake for the prevention of cardio-vascular disease (1). One gram (1,000 mg) of fish oil contains about 300mg EPA and 200mg DHA. Greater than 3 grams per day may increase bleeding in some individuals. For additional cardiovascular protection vegans may want to include foods high in the short-chain omega-3 fatty acids such as flaxseed, chia seeds and walnuts in their diet.

      Unfortunately, many Naturopathic Doctors recommend mega-doses of omega-3 fatty acids (1-3 grams fish oil) to their patients because their normal patient is usually someone eating the Standard American Diet (SAD) high in omega-6 fatty acids (grains and grain seed oils) and saturated fats (meats, dairy) and very low in omega-3 fatty acids (green leafy vegetables, walnuts, flaxseed, chia seed). This diet style creates inflammation and the larger doses of omega-3′s may help to decrease it.

      However, a healthy diet of unrefined, plant-based whole foods rich in vegetables, fruits, unrefined grain, beans and legumes, with a few ounces of raw nuts or seeds is anti-inflammatory; therefore, high doses of DHA/EPA may not be necessary, nor optimal.

      1. Musa-Veloso, K., et al. Impact of low v. moderate intakes of long-chain n-3 fatty acids on risk of coronary heart disease. British Journal of Medicine (2011), 106,1129-1141.

      • Jen

        Hi Dr. Sanchez,

        I just wanted to thank you for your response. As an ND student and a vegan myself, this information will be very useful :) Thanks again!

  • Stephen Albers

    Dear Dr Greger,

    I am an anti- pill popper by nature. But I’ll willingly take one if the need is proven.

    You do an excellent job of researching Vitamin B12 tests. I took one which verified I do not have a B12 deficiency. So, with recurring monitoring, B12 suppliment is a pill I do not take.

    Now I’d like to ask you to do the same thing for comprehensive fatty acid profile tests for determining DHA/EPA STATUS. There are several tests on the market with costs ranging from $150 to $500. A home test is available from Omega Quant. Which of the available tests can be recommended?

    Sincerely,

    Stephen

    • Toxins

      The issue with vitmain b12 is that it takes a while for a person to become deficient and once you are deficeint its difficult to restore back to normal levels. There are no health detriments or side affects seen with taking a vitmain b12 supplement, as the excess is simply excreted through urine. Regardless of your philosophy, there is no reliable plant source of b12, and the most healthful approach is indeed to supplement b12. Dr. Greger has a whole series of videos on b12 seen here.

      http://nutritionfacts.org/index.php?s=b12

  • http://jolkapolkaskitchen.blogspot.com/ WholeFoodChomper

    Does any one have any thoughts (backed up by scientific evidence) regarding liquid lecithin? I just read on the EWG web-site that liquid lecithin is “A naturally derived vegetable product that was popularized by vegetarian chefs in the 1970s, lecithin is a healthy, affordable option to oil and synthetic cooking sprays which continues to be used in many professional bakeries and kitchens.” Is liquid lecithin really healthy and/or safe to use?

  • Sarah

    Hi, Dr. Greger:

    I am sending you this email to ask if vegetarians and vegans can meet their daily DHA requirements by eating seaweed or algae? Is taking an algae-based DHA supplement daily the only way to insure that vegetarians and vegans obtain enough DHA?

    Thank you!

  • http://www.facebook.com/profile.php?id=666366687 Stephen Lucker Kelly

    Little confused here? So should we be supplementing Omega 3? Or not in general? A lot of people say just eating flax, chia or walnuts is fine…

    • Andrea Kladar

      I saw a long presentation by Dr. Greger to a school and his recommendation was to take 1-2 tablespoons of ground flax every day to get adequate amounts of Omega 3.

  • FrancisLeblanc

    I understand that we should choose Algae based omega-3, but they are plenty of new company coming to the market. How can we choose a product where the sources are less than a few years old ? What are the most proven and respected products?

    • http://www.DonForresterMD.com/ Don Forrester MD

      I would review Toxins excellent post plus the other video’s relating to DHA/EPA and omega 6. I don’t recommend supplementation of DHA/EPA but if you or you in conjunction with your health care professional(s) decide to go this route then you should go algae based. I always tend toward more established companies with the best disclosures and information. It does get down to a certain level of trust when dealing with manufactured products.