Image Credit: Valerie Everett / Flickr. This image has been modified.

Bad Gut Flora Can Undermine Our Natural Liver Detox

Colon cancer is a leading cancer killer, yet there’s a paradox in Africa: Africans rarely get the disease, even in modern times when they are no longer eating their traditional whole food diet—that is, when they are no longer eating lots of fiber, fresh fruits, and vegetables. It is likely their continued low prevalence of colon cancer—50 times lower than ours—is related to their low intake of animal protein and fat, which I explored in my Solving a Colon Cancer Mystery video. But why would animal protein and fat increase cancer risk? Well, as I noted in my video Bowel Wars, if you eat egg whites, for example, about 5 to 35% of the protein isn’t digested and absorbed. Instead, it ends up in the colon, where it undergoes a process called putrefaction.

When animal protein putrefies in the gut, it can lead to the production of the rotten egg gas, hydrogen sulfide, which, in addition to its objectionable odor, can produce changes that increase cancer risk. Putrefying protein also produces ammonia.

Over a lifetime on a standard Western diet, the bacteria in our colon may release the amount of ammonia found in 1,000 gallons of Windex. At concentrations found day-to-day inside the colon on usual Western diets, ammonia destroys cells, alters DNA synthesis, increases cellular proliferation, may increase virus infections, and favors the growth of cancerous cells. The products of protein and fat digestion are to blame. We can double ammonia concentrations in the colon by eating a lot of meat.

However, if you put people on a plant-based diet, the enzyme activity that creates the ammonia in the colon drops like a rock within just one week.

Other bacterial enzymes are affected as well. For example, vegetables in the broccoli family can boost detoxifying enzymes in the liver. (See Prolonged Liver Function Enhancement from Broccoli for more on this.) These so-called phase 2 enzymes, UDP-glucuronosyltransferases, detoxify drugs and chemicals by applying a chemical straightjacket. They can deactivate the date rape drug GHB or take the carcinogens in meat, like benzopyrene, and render them harmless before dumping them back into the intestine for disposal. But, if our liver detoxifies it, why is benzopyrene in meat still associated with rectal cancer? Certain bacteria in our gut contain the opposite enzyme—that removes the straightjacket and frees the carcinogen to wreak a last bit of havoc before it leaves the body.

Within one week of eating plant-based, researchers found we can drop that enzyme activity in our colon by about 30%. But, this was with a raw, “extreme” vegan diet. What about a regular vegetarian diet? Compared to a pound-of-meat-a-day diet, those placed on a meat-free diet for one month experienced a 70% drop in “toxifying” activity. And, long-time vegetarians exhibit just a fraction of carcinogen-releasing activity compared to those on a standard American diet.

So, might this help explain the increased risk of colorectal cancer in the United States? Researchers put it to the test by taking biopsies from the lining of the colons of Americans versus Africans to measure cell proliferation rates, a marker for increased cancer risk and decreased cancer survival. As you can see in my Putrefying Protein and “Toxifying” Enzymes video, the researchers found proliferating cells throughout the colons of Caucasian-Americans and African-Americans, but only a few were seen in the African biopsies. The Africans had dramatically lower proliferation rates.

Overall, higher colorectal cancer risk was associated with “higher dietary intakes of animal products and higher colonic populations of potentially toxic hydrogen and secondary bile-salt-producing bacteria.”

And, while the researchers were getting the biopsies, they looked around a little: They detected only 4 problems out of the 18 African colons they looked at. Out of the 17 African-American and 17 Caucasian-American colons, however, they found 21 problems in each group, including polyps, diverticulosis, and lots of hemorrhoids. “The remarkably pristine condition of the colons in our African volunteers further supports our impression that [African] colons were, in general, far healthier than those of age-matched Americans.”

I encourage you to check out my Stool pH and Colon Cancer, How to Treat Kidney Stones with Diet, and Testing Your Diet with Pee & Purple Cabbage videos, which explain how we should strive to have an acidic environment in our colon (but alkaline in our kidneys).

For more on bowel health, see

In health,

Michael Greger, M.D.

PS: If you haven’t yet, you can subscribe to my free videos here and watch my live, year-in-review presentations:

Discuss

Michael Greger M.D., FACLM

Michael Greger, M.D. FACLM, is a physician, New York Times bestselling author, and internationally recognized professional speaker on a number of important public health issues. Dr. Greger has lectured at the Conference on World Affairs, the National Institutes of Health, and the International Bird Flu Summit, testified before Congress, appeared on The Dr. Oz Show and The Colbert Report, and was invited as an expert witness in defense of Oprah Winfrey at the infamous "meat defamation" trial.


79 responses to “Bad Gut Flora Can Undermine Our Natural Liver Detox

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  1. And so it is that the complexities and the elegant simplicity of sane eating. Each organ system, and even our minds and spirits, rely on us to eat Life vs. Death. What a concept!

    A proud monthly supporter of Nutritionfacts.org




    11
    1. HI I noticed that you will be having an event in St. Pete, Florida on November 15th and was reaching out to see if you would consider helping with our project of opening the first 100% plant-based public school in the US but helping to spread the word and get people to sign our petition or even donate.
      Here is more info on our school.
      A vegan school opening in Pinellas County/St. Pete, Florida could use your support by signing the petition AND sharing the petition : KING Charter Schools is going to happen! :) Check them out at http://www.kingcharterschools.org.
      —> Sign!
      https://www.thepetitionsite.com/takeaction/695/951/396/
      —> Donate! https://www.youcaring.com/kingcharterschools-992046
      —> Like!
      https://www.facebook.com/kingcharterschools/
      If you know of a business that could share on their website or any students or adults who would like to volunteer part time from hom,e please have them email us at
      kingcharterschools@gmail.com




      2
  2. So now I can’t even have my egg white omelet for breakfast with mushrooms and broccoli sprouts.

    Dr Mercola has just the opposite idea on fat, I wish Dr Gregor and Dr Mercola would do a video
    on “fat and meat” . They did do one or maybe two in the past on everything they agreed on.

    I’m mostly plant based but still have very small portions of meat several times a week and my
    beloved omelet for breakfast.




    5
    1. hi Frank, there are many videos available at this site if you need information on why a plant based diet is best. Here is a selection about animals derived proteins in the diet.

      https://nutritionfacts.org/topics/animal-protein/

      This collection will help clarify issues around fat consumption

      https://nutritionfacts.org/topics/saturated-fat/

      and here as well http://nutritionstudies.org/plant-oils-are-not-a-healthy-alternative-to-saturated-fat/
      I hope this will answer some of your questions. Be well !




      12
    2. Animal protein contains all of the toxins, anti-biotics, and hormones that the animal itself did. Phytolipids, on the other hand, contain none of these. Every cell, whether plant, animal, or microbe, contains fat.

      I like your dietary philosophy Frank; “the poison is in the dose.”




      2
      1. My solution:

        At the low end of the spectrum are branched chain amino acids – only 1% of their content is utilized by the body with 99% resulting in waste that your body must then process and eliminate.

        Whey and soy proteins – only 18% or less of their content is utilized by the body with 83% leaving as waste.

        Food like meat, fish and poultry fare a bit better with 32% being absorbed and 68% being wasted.

        Eggs are the winners in the food stakes with 48% being utilized and 52% converted to waste.

        Now compare those numbers to PerfectAmino – a massive 99% is put to work by the body, with only 1% leaving as waste. Not only that, but PerfectAmino is absorbed by the body within 23 minutes! And there is only 0.4 of a calorie per tablet.

        http://www.swansonvitamins.com/swanson-ultra-ajipure-9-essential-aminos-formula-pharmaceutical-grade-60-veg-caps

        https://www.amazon.com/gp/product/B0081KWNHY/ref=oh_aui_detailpage_o00_s00?ie=UTF8&psc=1

        Avoids the issues in the colon? Avoids sarcopenia?




        0
    3. I was thinking the same thing but seeing as we are not eating meat at all the load on our system will be so much lower that occasional omelettes might not be a concern. The other item is amount of protein. Your body can only break down so much at one meal so 2 small servings of egg white omelette might not be as bad as one large one.

      At least whey protein seems to be safe for colon. Maybe Dr Gregor can comment on studies like this one: https://www.ncbi.nlm.nih.gov/pubmed/11352868

      Full Text: http://cebp.aacrjournals.org/content/10/5/555.long

      “These results suggest that long-term consumption of whey protein may reduce the risk of colon cancer. “




      0
      1. You should read that study.

        it compared rats fed either casein or whey protein. 50% of the rats fed casein developed tumours compared to 30% of the rats fed whey protein.

        In both cases the rats were fed animal protein and in both cases many of the rats developed cancerous tumours. The study only shows that whey protein is “protective” versus casein.

        That is like saying 100 people were shot and 50% of them died, while 100 people were stabbed and 30% died so being stabbed is “safe”




        14
    4. Hi Frank!
      This morning we just tasted-tested Follow Your Heart’s VeganEgg. What a surprise! It not only looks like real egg, it cooks and tastes like egg. My husband was an egg-for-breakfast guy and has been missing that familiar scramble or omelet, and we’ve tried many egg substitute recipes, but none can compare to VeganEgg. He feels satisfied this morning. Check it out.




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    1. Thank you! Love that statement, “all the sense in the world”. Indeed, a WFPBD makes sense for this world. :)

      A proud supporter of Nutritionfacts.org




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  3. None of natures children (including microbes) can exist without fat; it is what keeps the organelles and membranes from dissolving into the cell’s cytoplasm.

    Animal fat is a witches’ brew however – ’tis packed full of toxins, hormones, and God only know’s what all else.




    5
    1. Human have been eating animal fat and saturated fat since antiquity.

      Vegetable oil and sugar were invented in modern times and that when human got sick.




      2
      1. please explain the eskimo corpses with severe atherosclerosis, in your exceedingly linear model of modern oil production

        all oil is poison, by the way. powerful drugs at best, toxic compounds at worst. if you want oil, get it from intact plant sources. not from a bottle.




        3
      2. This is fallacious reasoning, Jerry. Literally.

        It is called the Appeal to Antiquity Fallacy.
        https://en.wikipedia.org/wiki/Appeal_to_tradition)

        “Vegetable oil and sugar were invented in modern times and that when human got sick.”
        I don’t know how to break this to you Jerry but people also got sick and died before modern times.

        Your reasoning is also a prime example of the shocking double standards employed by saturated fat and animal food apologists. Yes people have been eating saturated fat (in meat and plants) since antiquity. They have also been eating oils and sugars (in plant foods) since antiquity. You can’t have it both ways Jerry – what is sauce for the goose is sauce for the gander.

        Well, unless you are a saturafed fat apologist of course.




        3
    2. Vegetable fats is the way to go avocado coconut oil olive oil nut oils No soy corn canola safflower sunflower oils GMO extracted with hexane high in inflammatory omega 6




      0
      1. Freya: vegetable fats in their whole foods form, yes. Not defined or extracted or processed like coconut oil , olive oil etc. Eat the olive. Eat the coconut. Eat the avocado. Etc. Sure, they taste better to.




        1
  4. talking about gut health and the advice to avoid meat and animal products in your diet is good advice , however i ran into someone who took the advice to brew his tea cold with no hot water.
    he said he had gotten that advice from nutritionfacts.org . not only did he not use a safer version black tea he used the most bacteria laden tea , white ! everyone in the family that consumed this cold brew was sick with cramps, nausea etc .
    perhaps it would be better to delete your video about cold brew tea.
    sites.psu.edu/kff5054eportfolio.com/…/Bacterial-Growth-and -Morphology-From-Tea.pdf




    3
    1. The link you provided doesn’t work. An extra space crept into the address I think. This one should work.
      http://sites.psu.edu/kff5054eportfolio/wp-content/uploads/sites/42497/2016/03/Bacterial-Growth-and-Morphology-From-Tea.pdf

      However, in that experiment, the teas were allowed to stand for seven days at room temperature. When I steep cold tea, I do it overnight in the fridge and I have never experienced nay consequent sickness.

      It sounds to me like your friend and his family had food poisoning. I doubt that the tea had anything to do with it. I suspect that we would have had reports before now if cold white tea regularly did this to people. And we haven’t.




      3
      1. TG
        Thanks for correcting the link in my first comment . It was the tea causing their distress , because I did not tell you it wasn’t a one time thing , there were three adults and two teenagers in the house ,the adults drank the tea everyday , at first no one really noticed anything . Then one day one of them said my gut is so sore and cramping I must be coming down with the flu , which surprised the other two for they too had the same thing . They started blaming all sorts of things , but could not pinpoint it . When they realized the teens were fine and they were getting worse and worse , they concluded it must be the tea . So nobody drank the cold brew tea for several days and then after about 5 days one of them tried the cold brew and within hours was cramping again , so that was the last time they tried the tea.
        I would also point out that if you did a search at “Food Safety News” look under iced tea safety they do not recommend cold brew tea or sun tea or whatever you call it . While they admit they have not received any complaints about people getting sick from iced tea , they do have recommendations to make ice tea safely . What is interesting is in their comment section they have a number of commenters who claim they were made extremely sick from iced tea.




        2
        1. Thanks. But concerning the last comment in your post, those reports were not specific to white tea?

          They seem to serve iced tea iced tea everywhere in the Philippines where I am at the moment, There don’t seem to be any problems. I don’t touch it myself because it is loaded with sugar. Perhaps that makes a difference. Sugar is a well-known anti-microbial agent.

          Similarly, I have never had any problems drinking with steeped white tea. Of course, I add lemon juice or a local citrus equivalent. Citrus juices are also antimicrobial.
          https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708628/

          What I am saying, I suppose, is yes letting your steeped tea stand at room temperature is probably not healthy. But who is going to do that anyway? And as for the family’s story you reported, I don’t think that one second hand report constitutes a reasonable argument that steeped white tea is dangerous.

          IMHO, you seem to be drawing a very long bow here.




          2
  5. I would love to have better gut flora but every 6 months I am ordered to take antibiotics to prevent infection to my new total replacement hip, prior to dental cleaning. Do I have an alternative choice other than antibiotics? I would love for Dr. Gregor to address this issue in the near future with a blog or video.
    Thank You ahead of time,
    Dennis Swigart




    4
    1. I”ve never ever heard of taking antibiotics to prevent infection. What about colloidal silver? If your immune system isn’t compromised, then why take it? Worth it to ask around.




      0
      1. There is evidence that colloidal silver taken internally can be unhealthful.

        “Colloidal silver is LIKELY UNSAFE when taken by mouth, applied to the skin, or injected intravenously (by IV). The silver in colloidal silver products gets deposited in vital organs such as the skin, liver, spleen, kidney, muscle, and brain. This can lead to an irreversible bluish skin discoloration that first appears in the gums. It can also stimulate melanin production in skin, and areas exposed to the sun will become increasingly discolored.”
        https://www.webmd.com/vitamins-supplements/ingredientmono-779-colloidal%20silver.aspx?activeingredientid=779

        And the science-based medicine website is pretty scathing
        https://sciencebasedmedicine.org/hi-ho-silver/




        1
    2. Vegetable fats is the way to go avocado coconut oil olive oil nut oils No soy corn canola safflower sunflower oils GMO extracted with hexane high in inflammatory omega 6




      0
    3. Therapeutic grade essential oils are antiviral antibacterial antifungal lok up thieves blend can be taken in a capsule Tou could take 3 spaced dosages about 15-20 drops on s capsule & also inhaled & applied on the bottoms of your feet where you have your largest pores & it won’t irritate Do some research on healing with essential oils I’ve personally been using them for 15-20 years & have taken classes in their use They’re bioavailabile to the body because they have one less constituency less than human blood & protect the plants from disease Only use high grade like young living or doterra which can be taken internally according to the type good luck




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    4. Dennis,

      in this case, you should go with antibiotics because these infections can be pretty dangerous. It’s not just some mild tonsillitis. You can of course help to preserve your gut flora with probiotics, fiber…

      I forwarded your request to Dr. Greger. :-)

      Moderator Adam P.




      0
  6. Lots of lions and tigers walking around with colon cancer. Cmon vegans wake up and smell the coffee. Little bit tie studies without any knowledge of the complete diet. N=1 studies without any knowledge of the amount of sugar, vegetable oil, grains. Keep throwing out the yolk the most nutritious part of the egg. O:).




    3
    1. so if we eat meat what can we take to lessen or eliminate this putrification of protein in the colon ? any supplemental eznyme or other supplement ?




      0
      1. The answer is: No. I’m not “meat shame-ing” you, but everyone is always seeking a rationale to keep their unhealthy habits. This reminds me of my patients that are so proud that they smoke “organic cigarettes” as if there was any significant health benefit. There is not. As Nancy alluded to here: don’t eat any animal products. If you have the overwhelming urge to do so, eat “fake meat.” These are not healthy, but good substitutes if you just don’t have the will power to avoid animal products. My favorite is the Gardein meat balls and chicken. For the meat balls: cut in half, stir fry, pour vegan marinara sauce all over this, put on a baguette, eat. It tastes EXACTLY like a real meatball sandwich (better than the real thing in my opinion) and has completely fooled EVERY meat eater that I’ve tested it on. Again, this is not healthy (due to added sodium and fat), but a viable substitute in an emergency. You’ll find that if you don’t eat meat for several months, the idea of eating it again will “gross you out”.

        Dr. Ben




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    2. It is important to look at the evidence if we want the facts.

      However, if you just want to justify your present diet, any claim or half-baked analogy will probably do though.

      On the other hand, some of those claims look a bit foolish. Lions and tigers for example.have very different digestive systems than humans, including higher stomach acidity to digest meat. You are comparing apples and oranges




      6
      1. Just for interest. i had a look at some of the studies on big cats. The paper below reporting on a genomic analysis of the big cats (and other carnivores compared to omnivores and herbivores) made some interesting observations about their adaptations to meat eating including this

        “Interestingly, three genes (MEP1A, ACE2, and PRCP), which are involved in the protein digestion and absorption pathway, had function altering AACs specific to Felidae species (Additional file 2: Figures S9–S11). We interpret this result as a dietary adaptation for high meat consumption that is associated with an increased risk of cancer in humans [46], and that the heme-related reactive oxygen species (ROS) in meat cause DNA damage and disrupt normal cell proliferation [47, 48]. We speculate that the functional changes found in DNA damage and repair associated genes help reduce diet-related DNA damage in the felid species. This possible felid’s genetic feature can lead to better understanding of human dietary and health research [34].”
        https://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-1071-4




        4
      1. Jerry

        People have been eating each other since antiquity, people have been consuming alcohol since antiquity, they have also been consuming their own urine since antiquity. People have also been tattooing themselves since antiquity and engaging in all sorts of bodily (self) mutilations. The fact that people have been doing something since antiquity does not prove that it is healthful. I would have thought this was self-evident. Not to you though,it seems. This appeal to antiquity is a well-known logical fallacy.
        http://www.logicalfallacies.info/relevance/appeals/appeal-to-tradition/

        It makes about as much sense as saying let’s ignore all the evidence about meat and human cancer because lions and tigers eat lots of meat and they don’t get colon cancer so it must be safe for humans to eat lots of meat.

        Your standard of thinking obviously did not improve over the weekend. You remain a great worry Jerry given your outlandish statements and illogical thinking. Your claim that all the evidence found from research around the world over the last 50+years identifying dietary saturated fat and high plasma cholesterol has been “faked” is just bizarre.

        It is known that high saturated fat consumption and high plasma cholesterol are risk factors for cognitive/neurological dysfunction and dementia. This has been pointed out to you before but memory deficits are apparently common in cognitive decline:

        “Of all the different types of fatty acids, the findings are most consistent for an increased risk of cognitive decline with a higher intake of saturated fatty acids.”

        ” The most established genetic risk factor for AD is the apolipoprotein E (APOE)-ε4 allele, which has been associated with nearly a doubling in the risk of developing AD (Bennett et al., 2003; Evans et al., 1997). ApoE encodes one of several proteins involved in cholesterol transport between the gut, liver, and peripheral tissues and they are the predominant cholesterol transport proteins in the brain. A number of cohort studies that measured total blood cholesterol in mid-life found that participants with higher levels of total cholesterol or hypercholesterolemia had an increased risk of developing dementia in late-life compared with the participants who had normal or low cholesterol levels (Beydoun et al., 2010; Kivipelto et al., 2002; Mainous et al., 2005; Notkola et al. 1998; Reynolds et al., 2010; Solomon et al., 2007; Solomon et al., 2009; Whitmer et al., 2005).”
        https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107296/

        Could these explain the poor cognitive functioning that characterises your posts?




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    3. @Ed and Jerry: Cmon carnists, wake up and make the connection. Cognitive dissonance at it finest with regards to both nutrition and compassion.




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  7. It’s interesting that many cultures eat high antioxidant foods with meat: quince with meat in Turkey and Iran. Cinnamon and cumin in the Middle East, Chiles, radishes, and cilantro in Mexico, oregano and rosemary in the Mediterranean. Also very few cultures just eat a giant slab of meat. Many eat a little meat mixed in with other stuff.




    3
    1. ‘Emma has always eaten very few vegetables, very little fruit. When I met her, she ate three eggs per day, two raw in the morning and then an omelette at noon, and chicken at dinner,’ said Mr Bava, who has been her doctor for the past 27 years.




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      1. Jerry Lewis
        Emma does not prove a whole lot , maybe if she was WFPB she live to be 150 .
        We had a house guest for 3 long months last year , she was 81 and maybe 75 lb. , she chain smoked , drank between 6 to 8 beers a day and I can hardly still believe this , but never ate more than 2 tablespoons of food daily .Sharp mind ,read a lot , did crossword puzzles and slept a lot . Her 3 kids had exactly same lifestyle as her , they are all gone ,died between 45 and 60 . It only proves some can get away with lots of bad habits , most of us can.t .




        4
    1. Jack, eat more. Seriously. Also, eat more starchy foods: sweet and white potatoes, parsnips and turnips. Eat more whole grains: barley, oatmeal, whole wheat bread. Eat nuts and legumes.




      0
  8. There is no doubt that eating plant foods and foods to enrich the gut flora is a must do for everyone, for all health aspects. But saying that eating meat, dairy and eggs is the cause of colon cancer is totally misleading. According to the following statistics, it is a mix bag to the cause of colon cancer. In countries where people supposedly eat some vegetables such as South Korea, they rank at the top in colon cancer rate. In countries where people eat animal foods such as the lousy USA or Iceland, Israel, France, they either don’t make the top 20 or don’t even make the list. Despite eating a SAD diet, the colon cancer rate in the USA is only 14.5 per 100.000 and we don’t even make the top 20.

    http://www.wcrf.org/int/cancer-facts-figures/data-specific-cancers/colorectal-cancer-statistics

    https://seer.cancer.gov/statfacts/html/colorect.html

    And egg is among the most nutritious and beneficial foods on earth. People have been eating eggs since ancient time.

    https://quatr.us/southeast-asia/history-eggs-eggs-come.htm

    P.S. I expect to see the guy from down under coming in with a rage and post a page long post with one hundred links (but nobody have any idea about what he talks about but that’s another story) since it’s now his day time.




    1
    1. Jerry that’s a low blow and an untrue dig about the “man down under”. I for one look forward to his posts. They are far more educational and thought provoking then the broken record tripe you keep peddling.




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      1. Me too, Racquels, I always look forward to TG’s posts. They’re always informative, well thought out & backed by scientific evidence. He’s such an asset to to this forum!




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    2. Jerry

      Regarding eggs and colorectal cancers, this association has been observed over many years. For example, his 1994 review of previous studies concluded

      ” Notably, in every study that met specific design criteria (defined a priori), risk estimates were consistent with a positive association. Two studies reported seven- to eight-fold increases in risk with high egg consumption.”
      https://www.ncbi.nlm.nih.gov/pubmed/8061589




      2
  9. Hi, I’ve been vegan last 4 months as a detox to reduce my cholesterol which is extremely high. Contemplating after doing a lot of research to do a more Mediterranean diet with adding occasionally good quality meat and diary. My background is Greek so that would make more sense. I don’t won’tto give up a tablespoon of gelaton I add to my green smoothie. Does Dr Greger or anyone have any knowledge. I tried searching this site but nothing on gelaton. I have read its very beneficial.




    0
    1. @Jina: if you consume animal parts and/or their secretions, then you’re not vegan. Please don’t use that word as it confuses people. You’re likely eating whole food plant based, which is great, and for optimum health Dr Greger would recommend continuing with that.

      Leave out the gelatin to: How gelatin is made




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    2. Unfortunately all the available evidence of what you’re doing is that it’s unhealthful. The real Med diet was nothing but fresh fruits and veggies. People that eat dairy and meat tend to die younger and sicker than those that don’t eat any animal products. If you eat animal products, your cholesterol will go up, but it may not show up on the standard test because the test is done fasting, which is not an accurate reflection of your average cholesterol levels.

      Gelatin is animal derived from collagen. There is zero peer-reviewed clinical evidence supporting any health benefits.

      Dr. Ben




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  10. Gelatin is certainly very fashionable but I am not aware of any credible studies on the long term health effects of regular consumption.

    WebMD comments:

    “There is some concern about the safety of gelatin because it comes from animal sources. Some people are worried that unsafe manufacturing practices might lead to contamination of gelatin products with diseased animal tissues including those that might transmit mad cow disease (bovine spongiform encephalopathy). Although this risk seems to be low, many experts advise against using animal-derived supplements like gelatin.”
    ://www.webmd.com/vitamins-supplements/ingredientmono-1051-gelatin.aspx?activeingredientid=1051




    3
    1. I think there’s a strong case for more glycine in the diet, and gelatin is a good source, though using pure glycine as one’s sweetener is more cost effective and probably better, health wise.

      The issue with gelatin (and other products from animal connective tissue) would be its high content of hydroxyproline, which is metabolized to glyoxylyate and oxalate, with a potential for kidney stones. Gelatin feeding increases urinary oxalate in humans. In pigs, high hydroxyproline feeding induces oxalate lithiasis and kidney damage in just 21 days.




      4
    2. Gelatin consists
      of 35% glycine, 16% proline, 14% hydroxyproline,
      11% alanine, and other
      amino acids. The only other animal
      product that contains hydroxyproline is elastin, and it has much lower
      concentrations.

      Since I’ve been adding gelatin
      to my nutritional program, I’ve
      noticed a very significant improvement
      in my SWS (slow wave sleep) and overall sleep.
      This morning I noticed that I had
      slept through two phone calls and
      three text messages during the
      night, which would have never
      happened before I started taking
      gelatin. I’ve been waking up early
      without any help, and I feel totally
      refreshed.

      I’ve noticed I have far less stiffness
      and joint soreness after either
      working out or inactivity.
      I’ve experienced positive changes
      in my energy levels, hair and nail
      strength, and skin tone. I’ll admit
      these are only subjective observations
      and something hard to
      quantify. Frankly, I take these types
      of improvements as bonuses. I understand
      the most valuable benefits
      are probably the ones I can’t see.
      My dosage levels have varied.

      Many of the studies incorporated
      10 grams a day (which is about 2½
      teaspoons; one teaspoon of gelatin
      is just over 4 grams). I would say
      now I’m routinely taking about
      25 grams a day (two tablespoons).

      Dr D Williams

      * I put a rounded TBS in soup now and then.




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  11. Other issues too. The amount of fecal sulfides (mostly hydrogen sulfide) varied in proportion to meat intake in this metabolic ward study. If you wonder why animal product consumption yields horrible smelling farts, its the high proportion of sulfur containing amino acids.

    A rather interesting animal study from this year found that diets with excess protein reduced microbial diversity, and increased levels of opportunist microbes, whereas low protein diets benefits a “guild” of beneficial microbes that rely on secreted mucin as their nitrogen source.




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  12. So back to the putrification and bad gas linked to colon cancer. What if a plant based diet causes this gas. Are you at the same risk. Is it the same cause?




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    1. LC,
      The nitrification and bad gas caused by meat products is due to hydrogen sulfide and ammonia production. Meat based diets tend to be excessive in protein and thus more sulpher and nitrogen to make ammonia and hydrogen sulfide gas. The gas produced in plant based diets tends to be due to carbohydrates that we lack the enzymes to fully digest. This gas tends to lessen as our microbiome changes on a plant based diet to produce more health promoting enzymes instead of the toxifying enzymes on meat based diets .If you have time here is an excellent description on how the gut changes based on our diet. https://www.nutritioncme.org/course/3215




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  13. SO more of the digestive enzyme that digests meat when we eat meat should do the trick ? if we lack then we add then…and of this harmful byproduct that is left over after we eat meat….reduced by antioxidents…i dont eat alot of meat but when i do a nice grilled steak is very tasty….i dont deny it….just looking for ways to reduce the harmful after affects….must be a way…always is…if not then science hasnt found it yet…for every dis ease there is always a counter measure…if not then science hasnt found it yet or refuses to




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    1. Lou, it all depends how many bullets you want to put in your gun for your game of dietary Russian roulette.
      Seriously, eating meat isn’t going to kill you quickly in most cases. Carnists often live to be very old. Of course, they are usually fat and unhealthy, but hey, take your chances. Just remember, the muscle you are eating was taken from a sensitive, sentient being with emotions and who died in terror so you could have your “tasty” dead flesh.




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