What are the pros, cons, and efficacy of dihydronicotinamide riboside (reduced NR), perhaps the most potent NAD+ precursor, as well as reduced NMN, taking NAD+ directly, or making it from scratch from tryptophan?
NR may just be a waste of money, safe but ineffective. NMN seems similarly useless in humans, but it may not even be safe.
The suppression of NAD+ synthesis by NR in humans may explain the disparate rodent results.
The metabolism of NAM may deplete our methylation capacity, interfering with the normal metabolism of hormones and neurotransmitters, and produce a neurotoxic compound in the process.
Given niacin’s decades of use as a cholesterol drug, we have a good idea of its safety profile.
The effects of NAD+ boosters on aged rodents have been described in the medical literature as “profound,” “dramatic,” and “remarkable,” but do they help people?
What is NAD+ and what role does it play in the aging process?
The pros and cons of all the NAD+ supplements and what are the ways to boost NAD+ naturally with diet and lifestyle?
A century ago, the age of first menstruation averaged as late as nearly 17. Why is sexual maturity coming so much earlier now?
Inhibiting mTOR, the “master determinant of lifespan,” is considered the best validated aging regulator.
Laser therapy is marketed as a promising alternative to drugs and scalpels for treating hair loss, but what does the research say?
What were the findings of an analysis of common, non-drug, non-supplement, non-lifestyle approaches to dementia prevention and treatment?
I assumed that collagen proteins would get completely broken down in the digestive tract, but I was wrong.
How do two common supplements stack up against glaucoma, the leading cause of irreversible vision loss in the world?
In this live lecture, Dr. Greger offers a sneak peek into his latest book, How Not to Age, a New York Times Best Seller.
Some animals, like the immortal jellyfish, can effectively live forever, so why can’t we?
Learn about my newest book, How Not to Age, a New York Times Best Seller.
