What are the effects of spinach and berries on oxidative stress, inflammation, and muscle soreness in athletes?
Flashback Friday: Foods to Improve Athletic Performance and Recovery
Below is an approximation of this video’s audio content. To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video.
Higher fruit and vegetable consumption was found to be “positively associated with muscle power” in adolescents, but that’s not who really needs it. What about the “consumption of fruit and vegetables and risk of frailty” in the elderly? Higher “[fruit and vegetable] consumption was associated with…lower…frailty” as well, “in a dose-response manner”—meaning more fruit, less frailty, and more vegetables, too. But these were all observational studies, which can’t alone prove cause and effect.
What happens when you put foods to the test? Well, “no positive influence…ingesting chia-seed oil on human running performance,” but there was an effect found for “spinach supplementation on exercise-induced oxidative stress.” And, by spinach supplementation, they meant they just gave some guys some fresh raw spinach leaves—one gram per kilo. So, like a quarter of a bunch a day for two weeks, and then they had them run a half-marathon. And, they found that “chronic daily oral supplementation of spinach”—uh, meaning like eating a salad—”has alleviating effects on known markers of oxidative stress and muscle damage.”
Here’s what happens when you run a half-marathon without spinach: a big spike in oxidative stress, blood malondealdehyde levels, that stay up hours or even days later. In the spinach group, the before-and-after two weeks of spinach doesn’t seem to make much of a difference. But, put the body under pressure, and then you can really see the difference. Your body is better able to deal with the stress.
And, if you look at the resulting muscle damage, as measured by creatine kinase leakage from your muscles (an enzyme that should be in your muscles, not leaking out into your blood), you start out at about 100, and go up to 200 after the half-marathon. Right after, two hours later. But, it’s the next day where you really feel it—that delayed-onset muscle soreness, with CK levels reaching 600 before coming back down. That’s without spinach, though. On spinach, you get a similar immediate post-race bump, but it’s that next day where spinach really shines. You don’t get the same next-day spike. So, for a competitive athlete, that quicker recovery may get you back training harder sooner. They attribute this to “the anti-inflammatory effects of spinach.”
Same with black currant juice. After some hardcore weight lifting, muscle damage indicators go up and stay up, whereas the same lifting, drinking berries, and it goes up, but comes right back down. But, these were just measures of a biomarker of muscle soreness. What about actual soreness?
If you look at the effects of tart cherry juice “on recovery following prolonged, intermittent” sprints in soccer players, you see the same kind of reduction in biomarkers of inflammation—but, more importantly, less resulting muscle soreness. Here’s the soreness reported in the days afterwards in the placebo group. Only about half in the cherry group. Then, they measured maximum voluntary isometric contractions of the leg muscles, which understandably took a hit in the days after the intense workout, but not in the cherry group.
They conclude “that participants who supplemented with [a tart cherry concentrate] were able to maintain greater functional performance.” But, that was testing like how high can you vertically jump. They didn’t actually see if they played soccer any better. But, this study on purple grape juice actually showed “an ergogenic effect in recreational runners by promoting increased time-to-exhaustion,” where you ramp people up on a treadmill and see how long they can go before collapsing. After a month of drinking a grape Kool-Aid type placebo control drink, no real change in performance, but a whopping 15% improvement in the real grape group, who hung on for another 12 minutes.
These studies used juice, so they could make a matched placebo control drink. But, you can buy Concord grapes fresh, or tart cherries fresh, frozen, or water-packed in a can. I mix them with oatmeal, cocoa, and mint leaves for a chocolate-covered-cherry type sensation. You may want to try that for a few days before participating in your next big sporting event.
Please consider volunteering to help out on the site.
- Wilson PB. Ginger (Zingiber officinale) as an Analgesic and Ergogenic Aid in Sport: A Systemic Review. J Strength Cond Res. 2015;29(10):2980-95.
- Warden SJ. Prophylactic use of NSAIDs by athletes: a risk/benefit assessment. Phys Sportsmed. 2010;38(1):132-8.
- Küster M, Renner B, Oppel P, Niederweis U, Brune K. Consumption of analgesics before a marathon and the incidence of cardiovascular, gastrointestinal and renal problems: a cohort study. BMJ Open. 2013;3(4)
- Lakhan SE, Ford CT, Tepper D. Zingiberaceae extracts for pain: a systematic review and meta-analysis. Nutr J. 2015;14:50.
- Van breemen RB, Tao Y, Li W. Cyclooxygenase-2 inhibitors in ginger (Zingiber officinale). Fitoterapia. 2011;82(1):38-43.
- Black CD, Oconnor PJ. Acute effects of dietary ginger on quadriceps muscle pain during moderate-intensity cycling exercise. Int J Sport Nutr Exerc Metab. 2008;18(6):653-64.
- Black CD, O'connor PJ. Acute effects of dietary ginger on muscle pain induced by eccentric exercise. Phytother Res. 2010;24(11):1620-6.
- Matsumura MD, Zavorsky GS, Smoliga JM. The Effects of Pre-Exercise Ginger Supplementation on Muscle Damage and Delayed Onset Muscle Soreness. Phytother Res. 2015;29(6):887-93.
- Mashhadi NS, Ghiasvand R, Askari G, et al. Influence of ginger and cinnamon intake on inflammation and muscle soreness endued by exercise in Iranian female athletes. Int J Prev Med. 2013;4(Suppl 1):S11-5.
- Neville CE, Mckinley MC, Murray LJ, Boreham CA, Woodside JV. Fruit and vegetable consumption and muscle strength and power during adolescence: a cross-sectional analysis of the Northern Ireland Young Hearts Project 1999-2001. J Musculoskelet Neuronal Interact. 2014;14(3):367-76.
- García-esquinas E, Rahi B, Peres K, et al. Consumption of fruit and vegetables and risk of frailty: a dose-response analysis of 3 prospective cohorts of community-dwelling older adults. Am J Clin Nutr. 2016;104(1):132-42.
- Nieman DC, Gillitt ND, Meaney MP, Dew DA. No positive influence of ingesting chia seed oil on human running performance. Nutrients. 2015;7(5):3666-76.
- Dugasani S, Pichika MR, Nadarajah VD, Balijepalli MK, Tandra S, Korlakunta JN. Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol. J Ethnopharmacol. 2010;127(2):515-20.
- Lantz RC, Chen GJ, Sarihan M, Sólyom AM, Jolad SD, Timmermann BN. The effect of extracts from ginger rhizome on inflammatory mediator production. Phytomedicine. 2007;14(2-3):123-8.
- Jolad SD, Lantz RC, Chen GJ, Bates RB, Timmermann BN. Commercially processed dry ginger (Zingiber officinale): composition and effects on LPS-stimulated PGE2 production. Phytochemistry. 2005;66(13):1614-35.
- Black CD, Herring MP, Hurley DJ, O'connor PJ. Ginger (Zingiber officinale) reduces muscle pain caused by eccentric exercise. J Pain. 2010;11(9):894-903.
- Bohlooli S, Barmaki S, Khoshkhahesh F, Nakhostin-roohi B. The effect of spinach supplementation on exercise-induced oxidative stress. J Sports Med Phys Fitness. 2015;55(6):609-14.
- Hutchison AT, Flieller EB, Dillon KJ, Leverett BD. Black Currant Nectar Reduces Muscle Damage and Inflammation Following a Bout of High-Intensity Eccentric Contractions. J Diet Suppl. 2016;13(1):1-15.
- Bell PG, Stevenson E, Davison GW, Howatson G. The Effects of Montmorency Tart Cherry Concentrate Supplementation on Recovery Following Prolonged, Intermittent Exercise. Nutrients. 2016;8(7)
- Toscano LT, Tavares RL, Toscano LT, et al. Potential ergogenic activity of grape juice in runners. Appl Physiol Nutr Metab. 2015;40(9):899-906.
Image credit: ponce_photography via Pixabay. Image has been modified.
Motion graphics by Avocado Video.
Below is an approximation of this video’s audio content. To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video.
Higher fruit and vegetable consumption was found to be “positively associated with muscle power” in adolescents, but that’s not who really needs it. What about the “consumption of fruit and vegetables and risk of frailty” in the elderly? Higher “[fruit and vegetable] consumption was associated with…lower…frailty” as well, “in a dose-response manner”—meaning more fruit, less frailty, and more vegetables, too. But these were all observational studies, which can’t alone prove cause and effect.
What happens when you put foods to the test? Well, “no positive influence…ingesting chia-seed oil on human running performance,” but there was an effect found for “spinach supplementation on exercise-induced oxidative stress.” And, by spinach supplementation, they meant they just gave some guys some fresh raw spinach leaves—one gram per kilo. So, like a quarter of a bunch a day for two weeks, and then they had them run a half-marathon. And, they found that “chronic daily oral supplementation of spinach”—uh, meaning like eating a salad—”has alleviating effects on known markers of oxidative stress and muscle damage.”
Here’s what happens when you run a half-marathon without spinach: a big spike in oxidative stress, blood malondealdehyde levels, that stay up hours or even days later. In the spinach group, the before-and-after two weeks of spinach doesn’t seem to make much of a difference. But, put the body under pressure, and then you can really see the difference. Your body is better able to deal with the stress.
And, if you look at the resulting muscle damage, as measured by creatine kinase leakage from your muscles (an enzyme that should be in your muscles, not leaking out into your blood), you start out at about 100, and go up to 200 after the half-marathon. Right after, two hours later. But, it’s the next day where you really feel it—that delayed-onset muscle soreness, with CK levels reaching 600 before coming back down. That’s without spinach, though. On spinach, you get a similar immediate post-race bump, but it’s that next day where spinach really shines. You don’t get the same next-day spike. So, for a competitive athlete, that quicker recovery may get you back training harder sooner. They attribute this to “the anti-inflammatory effects of spinach.”
Same with black currant juice. After some hardcore weight lifting, muscle damage indicators go up and stay up, whereas the same lifting, drinking berries, and it goes up, but comes right back down. But, these were just measures of a biomarker of muscle soreness. What about actual soreness?
If you look at the effects of tart cherry juice “on recovery following prolonged, intermittent” sprints in soccer players, you see the same kind of reduction in biomarkers of inflammation—but, more importantly, less resulting muscle soreness. Here’s the soreness reported in the days afterwards in the placebo group. Only about half in the cherry group. Then, they measured maximum voluntary isometric contractions of the leg muscles, which understandably took a hit in the days after the intense workout, but not in the cherry group.
They conclude “that participants who supplemented with [a tart cherry concentrate] were able to maintain greater functional performance.” But, that was testing like how high can you vertically jump. They didn’t actually see if they played soccer any better. But, this study on purple grape juice actually showed “an ergogenic effect in recreational runners by promoting increased time-to-exhaustion,” where you ramp people up on a treadmill and see how long they can go before collapsing. After a month of drinking a grape Kool-Aid type placebo control drink, no real change in performance, but a whopping 15% improvement in the real grape group, who hung on for another 12 minutes.
These studies used juice, so they could make a matched placebo control drink. But, you can buy Concord grapes fresh, or tart cherries fresh, frozen, or water-packed in a can. I mix them with oatmeal, cocoa, and mint leaves for a chocolate-covered-cherry type sensation. You may want to try that for a few days before participating in your next big sporting event.
Please consider volunteering to help out on the site.
- Wilson PB. Ginger (Zingiber officinale) as an Analgesic and Ergogenic Aid in Sport: A Systemic Review. J Strength Cond Res. 2015;29(10):2980-95.
- Warden SJ. Prophylactic use of NSAIDs by athletes: a risk/benefit assessment. Phys Sportsmed. 2010;38(1):132-8.
- Küster M, Renner B, Oppel P, Niederweis U, Brune K. Consumption of analgesics before a marathon and the incidence of cardiovascular, gastrointestinal and renal problems: a cohort study. BMJ Open. 2013;3(4)
- Lakhan SE, Ford CT, Tepper D. Zingiberaceae extracts for pain: a systematic review and meta-analysis. Nutr J. 2015;14:50.
- Van breemen RB, Tao Y, Li W. Cyclooxygenase-2 inhibitors in ginger (Zingiber officinale). Fitoterapia. 2011;82(1):38-43.
- Black CD, Oconnor PJ. Acute effects of dietary ginger on quadriceps muscle pain during moderate-intensity cycling exercise. Int J Sport Nutr Exerc Metab. 2008;18(6):653-64.
- Black CD, O'connor PJ. Acute effects of dietary ginger on muscle pain induced by eccentric exercise. Phytother Res. 2010;24(11):1620-6.
- Matsumura MD, Zavorsky GS, Smoliga JM. The Effects of Pre-Exercise Ginger Supplementation on Muscle Damage and Delayed Onset Muscle Soreness. Phytother Res. 2015;29(6):887-93.
- Mashhadi NS, Ghiasvand R, Askari G, et al. Influence of ginger and cinnamon intake on inflammation and muscle soreness endued by exercise in Iranian female athletes. Int J Prev Med. 2013;4(Suppl 1):S11-5.
- Neville CE, Mckinley MC, Murray LJ, Boreham CA, Woodside JV. Fruit and vegetable consumption and muscle strength and power during adolescence: a cross-sectional analysis of the Northern Ireland Young Hearts Project 1999-2001. J Musculoskelet Neuronal Interact. 2014;14(3):367-76.
- García-esquinas E, Rahi B, Peres K, et al. Consumption of fruit and vegetables and risk of frailty: a dose-response analysis of 3 prospective cohorts of community-dwelling older adults. Am J Clin Nutr. 2016;104(1):132-42.
- Nieman DC, Gillitt ND, Meaney MP, Dew DA. No positive influence of ingesting chia seed oil on human running performance. Nutrients. 2015;7(5):3666-76.
- Dugasani S, Pichika MR, Nadarajah VD, Balijepalli MK, Tandra S, Korlakunta JN. Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol. J Ethnopharmacol. 2010;127(2):515-20.
- Lantz RC, Chen GJ, Sarihan M, Sólyom AM, Jolad SD, Timmermann BN. The effect of extracts from ginger rhizome on inflammatory mediator production. Phytomedicine. 2007;14(2-3):123-8.
- Jolad SD, Lantz RC, Chen GJ, Bates RB, Timmermann BN. Commercially processed dry ginger (Zingiber officinale): composition and effects on LPS-stimulated PGE2 production. Phytochemistry. 2005;66(13):1614-35.
- Black CD, Herring MP, Hurley DJ, O'connor PJ. Ginger (Zingiber officinale) reduces muscle pain caused by eccentric exercise. J Pain. 2010;11(9):894-903.
- Bohlooli S, Barmaki S, Khoshkhahesh F, Nakhostin-roohi B. The effect of spinach supplementation on exercise-induced oxidative stress. J Sports Med Phys Fitness. 2015;55(6):609-14.
- Hutchison AT, Flieller EB, Dillon KJ, Leverett BD. Black Currant Nectar Reduces Muscle Damage and Inflammation Following a Bout of High-Intensity Eccentric Contractions. J Diet Suppl. 2016;13(1):1-15.
- Bell PG, Stevenson E, Davison GW, Howatson G. The Effects of Montmorency Tart Cherry Concentrate Supplementation on Recovery Following Prolonged, Intermittent Exercise. Nutrients. 2016;8(7)
- Toscano LT, Tavares RL, Toscano LT, et al. Potential ergogenic activity of grape juice in runners. Appl Physiol Nutr Metab. 2015;40(9):899-906.
Image credit: ponce_photography via Pixabay. Image has been modified.
Motion graphics by Avocado Video.
Republishing "Flashback Friday: Foods to Improve Athletic Performance and Recovery"
You may republish this material online or in print under our Creative Commons licence. You must attribute the article to NutritionFacts.org with a link back to our website in your republication.
If any changes are made to the original text or video, you must indicate, reasonably, what has changed about the article or video.
You may not use our material for commercial purposes.
You may not apply legal terms or technological measures that restrict others from doing anything permitted here.
If you have any questions, please Contact Us
Flashback Friday: Foods to Improve Athletic Performance and Recovery
LicenseCreative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
Content URLDoctor's Note
For research on other natural athletic interventions, see:
- Reducing Muscle Fatigue with Citrus
- Reducing Muscle Soreness with Berries
- Preventing Exercise-Induced Oxidative Stress with Watercress
- Fennel Seeds to Improve Athletic Performance
- Coconut Water for Athletic Performance vs. Sports Drinks
- Doping with Beet Juice
- Enhanced Athletic Recovery Without Undermining Adaptation
- The Gladiator Diet: How Vegetarian Athletes Stack Up
If you’re wondering about the oxalates in spinach and other greens, see Oxalates in Spinach and Kidney Stones: Should We Be Concerned? and Kidney Stones and Spinach, Chard, and Beet Greens: Don’t Eat Too Much.
If you haven't yet, you can subscribe to our free newsletter. With your subscription, you'll also get notifications for just-released blogs and videos. Check out our information page about our translated resources.