Transcript: Making Our Arteries Less Sticky
We’ve covered how to prevent the first step of atherosclerosis: decrease the level of bad cholesterol in our blood. What about blocking some of these other steps downstream?
“Both common and specialty mushrooms inhibit adhesion molecule expression and in vitro binding of monocytes to human aortic endothelial cells in a pro-inflammatory environment.” So, that means mushrooms may help block both this step, and this step.
Basically, what these researchers at Arizona State did was take the lining of a human artery, soaked it overnight with either nothing—the control group—or shiitake mushrooms, crimini mushrooms, oyster mushrooms, maitake mushrooms, or plain white button mushrooms. Then, they took away the mushrooms, washed the artery off, and added some monocytes, before and after inflammation.
So what we’d like to see is these bars come down—less monocyte adhesion. So, instead of being sucked into the walls of our arteries, they can go off and do their business elsewhere.
Which mushroom do you think worked the best? They all worked, but in another victory for this little funguy, plain old cheap white button mushrooms worked the best. And under inflammatory conditions, they found the same thing, but shiitake didn’t even seem to work much at all.
“The health implications are that diverse mushrooms, including common and specialty mushrooms can protect against cardiovascular disease by interfering with events that contribute to atherogenesis.”
To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video. This is just an approximation of the audio contributed by Serena.
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