Doctor's Note

For more magic from plain white mushrooms, see Vegetables Versus Breast Cancer and Breast Cancer Prevention: Which Mushroom is Best? Just make sure to cook them (see Toxins in Raw Mushrooms?). In terms of anti-inflammatory foods in general, check out Anti-Inflammatory AntioxidantsGarden Variety Anti-InflammationAspirin Levels in Plant Foods; and Dried Apples Versus Cholesterol. In terms of pro-inflammatory foods, see my four-part video series Improving Mood Through DietInflammatory Remarks About Arachidonic AcidChicken, Eggs, and Inflammation; and Chicken’s Fate is Sealed. If you missed it the first part in this series, check it out: Blocking the First Step of Heart Disease.

For further context, see my associated blog posts: The Most Anti-Inflammatory MushroomErgothioneine: A New Vitamin?Plant-Based Diets for Rheumatoid ArthritisMushrooms for Breast Cancer PreventionVitamin D from Mushrooms, Sun, or Supplements?; and Mushrooms and Immunity.

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  • Michael Greger M.D.

    For more magic from plain white mushrooms, see Vegetables Versus Breast Cancer and Breast Cancer Prevention: Which Mushroom is Best?. Just make sure to cook them (Toxins in Raw Mushrooms?). In terms of anti-inflammatory foods in general, check out Anti-Inflammatory Antioxidants, Garden Variety Anti-Inflammation, Aspirin Levels in Plant Foods, and Dried Apples Versus Cholesterol. In terms of pro-inflammatory foods, see the 4-part series Improving Mood Through Diet, Inflammatory Remarks About Arachidonic Acid, Chicken, Eggs, and Inflammation, and Chicken’s Fate is Sealed. If you missed it, please check out the previous video and any of the other 500 or so videos covering more than a thousand topics.

    • HemoDynamic, M.D.

      I always like your Punniness with your comments!!

  • Stefan Juhl M.D.

    Interesting (as always Dr Greger), but I find it a little difficult to extrapolate from this study design to conclude anything about the mushrooms in my veg-lasagne. The concentration “of mushroom” on the intima in the study, is probably several thousand times higher than I can obtain through diet.

    • HemoDynamic, M.D.

      Ah, you may be right Dr. Juhl, but again the key is a Varied. You probably read this but here is a quote from the Study conclusion:

       “These findings further support the notion that consumption of not only fruits and vegetables, but also dietary fungi, viz., mushrooms, is an important approach to minimizing CVD risk. Moreover, common, readily available and affordable mushrooms such as white button, or Agaricus bisporus, as well as specialty mushrooms including shiitake appear particularly beneficial to health.”

      I wouldn’t want to try the 10% Mushroom diet they spoke about in the study.  I will just use them as I like them. . . A BIG Portabella Mushroom Burger!

      How about this study: A 2009 case control study of more than 2000 women correlated a large decrease of breast cancer incidence in women who consumed mushrooms. Women in the study who consumed fresh mushrooms daily were 64% less likely to develop breast cancer, while those that combined a mushroom diet with regular green tea consumption reduced their risk of breast cancer by nearly 90%.
      That is if the statistics are interpreted correctly.

      Enjoy, my friend, a Fungi filled day.

      • Stefan Juhl M.D.

        Thanks. The study is of course interesting, and points in a direction. Does that sentence make sense in english?

        Information from epidemiological studies (e.g. The China Study) is very usefull in recommendations. The study you refer to also sounds very interesting.

        No fungi today – Dark Horse Lentil Soup with brown rice for dinner.

        Found a living beetle in my VEGETARIAN sandwich today. Got the money back…..

        • HemoDynamic, M.D.

          There they go trying to sneek a little animal protein in on ya without you knowing it ;-}
          Oh the Insanity of it all!

          • Stefan Juhl M.D.

            But could they not have killed it first? On the other hand: If they had tried with pork, it would probably also contain a little feces, so I think I would prefer the bug……

        • HemoDynamic, M.D.

          No the sentence didn’t make sense.  When I cut and paste sometimes my sentence gets cut off and I didn’t proof it before posting. 
          I stand corrected!

  • Dr. G., were the mushrooms used in the studies cooked or raw?


    • Stefan Juhl M.D.

      Good question. Problems with raw mushrooms?

    • HemoDynamic, M.D.

      From the study:
      “Harvested mushroom crops were randomly sampled, cleaned, sliced, and stored at 0°C for 24 h. Samples were later freeze-dried (Model 15 SRC-X; Virtis Genesis Co, Inc., Gardiner, NY), ground to a fine powder, and sieved through a 16 mesh screen. Mushroom powders were collected in sterile sample bags (Fisher Scientific, Pittsburgh, PA) and stored in the dark at room temperature in desiccators prior to analysis. After analyses, lyophilized mushroom powders were stored desiccated at -80°C in the dark until use.” this helps

    • Toxins

      We should try to consume mushrooms cooked simply because of some potential toxins found when raw.

    • alexih

      What about supplements such as this?

  • eicosatetraenoic

    Did anyone notice that this study was funded by “a grant from the Mushroom
    Council (San Jose, CA, USA) and the Australian Mushroom Growers
    Association”? Also, DMSO is a curious choice for a vehicle, and it could have interfered with the results.

  • Bhmosman

    The type is so small we can’t read it.

  • Good news.  I love mushrooms!

  • Dr Jim

    WOW! Who would have “thunk” that the white buttons beat out the shitake?! It’ll save me future expenses…….Dr.Jim

  • Raven

    The english journel of medicine – says that there is NO good Colestrol that is a mistake and that we need to watch both numbers…. what about that? So American medicine is behind on this?

  • Kate

    I am so glad I,ve found this site, I have been ill now since 1995, had a lot of illness one after another Unlucky me, now I am waiting on gallstone operation. Hope I can benefit from Dr. Greger’s Notes, and though diet and knowledge I’ll fined someway to help make my health better, he,s giving me a lot of reading to do, but it, great to fine at last a website that gives you in sites to all illness, as I can do more research into helping me build a better healthily way to a new life.

  • Ziba

    Thank you so much for all your posts and efforts, simply amazing.!!!

  • PLA

    I don’t see any videos/articles from Dr Greger on chondroitin sulfate. Does Dr Greger know if oral chondroitin sulfate helps remove cholesterol/plaque buildup in arteries? And if he is aware this helps, does he know of any reasons not to use this? I heard about chondroitin sulfate from Bill Sardi from his article online about Dr Lester Morrison at Loma Linda and his studies on heart disease in the 1960’s to 1980’s. Apparently Dr Morrison had great success with it (and he says it even helped to regrow hair!) Since it’s a sulfate….I’m wondering if it can cause colon issues like other sulfur containing substances that Dr Greger has talked about in his videos.

    • Joseph Gonzales R.D.

      Thanks for reposting! Chondroitin sulfate is made from bovine cartilage. It’s often suggested for bone health to reduce cartilage degeneration. I search pubmed and could not find anything on cholesterol. The main thing to consider is why would it be needed? Surely there are more natural ways to build bone and control cholesterol levels? I don’t think it’s the same type of sulfur found in dried fruit, like from this video.

      • PLA

        Thanks for the reply Joseph. Apparently Dr Morrison at Loma Linda had great success helping his patients clean out their clogged arteries with the chondroitin sulfate (1500 mg/day or more). Such a therapy would be incredibly valuable if even only for preventive therapy. Thanks for checking.

  • 4Baccurate


    Would mushrooms (or other foods) lessen, prevent, or alter for better or worse, collateral artery formation (angiogenesis) in a patient with peripheral artery disease (PAD)?

    Put differently, If we eat mushrooms to help keep tumors from forming their own blood supply—- Would mushrooms affect, for better or worse, angiogenesis in a patient with PAD?

    Thanks for your very excellent website.