Have you ever wondered if there’s a natural way to lower your high blood pressure, guard against Alzheimer's, lose weight, and feel better? Well as it turns out there is. Michael Greger, M.D. FACLM, founder of NutritionFacts.org, and author of the instant New York Times bestseller “How Not to Die” celebrates evidence-based nutrition to add years to our life and life to our years.

Macrobiotic Diet Pros and Cons

It’s the original counterculture diet.  But is the macrobiotic diet healthy?

This episode features audio from Pros and Cons of a Macrobiotic Diet and Benefits of a Macrobiotic Diet for Diabetes. Visit the video pages for all sources and doctor’s notes related to this podcast.


Welcome to the Nutrition Facts podcast.  I’m your host, Dr. Michael Greger.  I am thrilled that you have decided to join me today.  Because the more I learn about the latest in nutrition research–the more convinced I am that this information can make a real difference in all our lives.  And I like nothing better–than sharing it with you.

Today we evaluate the macrobiotic diet – the original counterculture diet from the 1960’s.  So, is it healthy?  What about today’s macrobiotic diet?  Let’s start with the pros and cons of a macrobiotic diet. 

Macrobiotic diets have been described by the American Medical Association as “one of the most dangerous dietary regimens, posing not only serious hazards to the health of the individual but even to life itself.” After all, macrobiotic diets are “predominantly vegetarian with a great emphasis…placed on whole grain[s].” What’s wrong with that? Well, they also used to tell people to not drink water, which isn’t good, and to avoid fruit—so much so it’s resulted in modern-day cases of scurvy.

Now thankfully, “[t]he macrobiotic diet has evolved over the past 30 years–an emphasis on whole grains, vegetables, and beans, while minimizing most meat, eggs, and dairy. I don’t like them restricting fruits; don’t like all the added salt; but compared to the standard American diet, it’s got a lot of things going for it. Only a quarter of the saturated fat intake, less than half the sugar intake, a very respectable fiber intake, two-and-a-half times the national average, but actually taking in more sodium. So, while the macrobiotic diet is an anti-inflammatory diet—has a negative dietary inflammatory index score, as opposed to the pro-inflammatory American diet—some of the most anti-inflammatory foods are herbs and spices. So, instead of adding all that sea salt and soy sauce, the macrobiotic diet could be improved by using natural seasonings instead.

Okay, but has the macrobiotic diet ever been put to the test? Yes, for diabetes. The restriction on water probably wouldn’t help, as “higher plain water [consumption] is associated with lower type 2 diabetes risk”—though part of that may be because they’re drinking less soda. And, fruit restriction is probably not helpful, since fruit consumption “is associated with a significantly reduced risk of type 2 diabetes” as well. But same with green leafy vegetables, which is where the macrobiotic diet can really shine: it includes lots of greens. Look, you can do randomized, double-blind, placebo-controlled, crossover studies of kale, and show that it suppresses the after-a-meal increase in blood sugars. Eat a meal of white rice, chicken, and eggs and get a big spike in blood sugar—though significantly less adding just a tablespoon of dried kale powder, as opposed to some kind of placebo powder (though the effect is visually exaggerated by their y-axis shenanigans).

And macrobiotic diets use whole grains, which can significantly improve insulin sensitivity compared to refined grains, which may be due in part to all the wonderful things fiber can do to help our good gut bacteria thrive—which could potentially lower inflammation, and decrease diabetes risk. But you don’t know…until you put it to the test.

Just three weeks on a strictly plant-based diet composed mostly of whole grains, vegetables, and beans and… they got about a 10% drop in blood pressure, a whopping 35% drop in LDL (bad) cholesterol, and a 38% drop in fasting blood sugars—in just 21 days. Were these changes statistically significant? Yes, the changes were significant in every possible way.

Similarly, short-term interventional studies on diabetics with these so-called Ma-Pi 2 macrobiotic diets have been performed across four continents. The “Ma-Pi” comes from the guy that came up with the diet, Mario Pianesi, a strictly plant-based diet based mostly on whole grains and vegetables, with legumes and some seeds, and decaf green tea as the preferred beverage. A near 40% drop in fasting blood sugars; near 27% drop in LDL cholesterol in 21 days.

Now, they did lose weight, a few pounds a week, but those kinds of results were way more than one would expect with weight loss, and—here’s the kicker—that 40% drop in blood sugars was after cutting their insulin in half! So those numbers greatly underestimate the effects. Better results, on fewer drugs. That’s the power of plants! All we need now is a randomized, controlled clinical trial to really seal the deal—which we’ll cover next.

In our final story we look at what happens when you add massive amounts of carbs to the daily diet of type 2 diabetics in the form of whole grains. 

Why are macrobiotic diets apparently so effective at reducing blood sugar levels in diabetes, within just a few weeks’ time? Because the diet is centered around whole grains—brown rice, barley, and mille, maybe the high fiber intake is improving the gut microbiome, the friendly flora in the colons of diabetics, and that’s leading to a reduction in insulin resistance? Or, maybe because it also has lots of vegetables, maybe it’s kind of correcting some kind of low-grade acidosis from the high levels of animal protein in their regular diets? Regardless, this was after just 21 days. Can macrobiotic diets also help with longer-term blood sugar control?

How about a six-month dietary intervention with wildly out-of-control blood sugars? Hemoglobin A1c offers a sense of one’s average blood sugars over the previous few months. So, an A1c level of 5 would mean over the last few months, your blood sugars have been in the double digits most of the time, meaning your sugars have been normal, healthy, non-diabetic. But an A1c of like 6 is pre-diabetes territory, and 6-and-a-half can be a sign of full-blown diabetes. But under 7 is considered controlled diabetes—that’s what diabetics are striving towards with pills and insulin injections. And anything over 7 is considered out-of-control diabetes. The average A1c level in the macrobiotic diet study started out off the charts at 12.6, meaning for months they had been averaging blood sugars in the 300s, despite all being on insulin injections.

But then, they were placed on this so-called Ma-Pi 2 diet, a strictly plant-based macrobiotic-style diet centered around whole grains, vegetables, and beans, with some sesame seeds and green tea. What happened? A1c levels started out with a wildly out-of-control diabetic 12.6, despite daily insulin injections, and six months eating that diet, ended up averaging a non-diabetic 5.7. And, are you ready for this? That was after they all were able to eliminate their insulin!  They went from 100% on insulin with out-of-control diabetes to 0% on insulin averaging non-diabetic blood sugars. That’s the power of plants! And three-quarters were off all their diabetes medications completely—in just six months’ time. And what are the side effects? How about LDL-cholesterol dropping 20%, triglycerides dropping nearly 40%—though, of course, anyone starting a strictly plant-based diet must ensure a regular, reliable source of vitamin B12.

All we need now is a randomized, controlled trial, and here it is. Type 2 diabetics randomized to the macrobiotic diet versus the recommended like American Diabetes Association-type diet. So, here’s an example of a typical day on the macrobiotic diet: a savory whole grains cake for breakfast with green tea, with brown rice sesame balls for a snack; lunch was a vegetable millet soup and brown rice salad, with lots of vegetable sides, and adzuki beans, more whole grain snacks; and a dinner similar to lunch: vegetable barley soup, lots of vegetables, chickpeas, green tea throughout the day.

Whereas the more standard diabetic-diet group got a day like this: low-fat milk, whole wheat bread, kind of a Mediterranean lunch with vegetables and beans, fruit for a snack, and a bean-and-vegetable soup, whole grain bread, and baked fish. I have to say that’s a pretty healthy control diet. I mean, they could have compared it to some trashy diet, but they wanted to be like look, this is what the diabetes groups say is best, so let’s stack our diet against theirs. Okay, so what happened?

The macrobiotic diet won out on every measure of blood sugar control. They all started out with fasting blood sugars in the 120s. That’s bad, but they were, after all, diabetics. Normal fasting blood sugars, like when you wake up in the morning before breakfast, should be at least down in the double digits, under 100. When they put people on this relatively healthy Diabetes Association diet, their blood sugars got better over the three-week study, from the 120s down into the one teens. So, that’s like the best the official diabetes-recommended diets can do.

Compare that to an isocaloric macrobiotic diet, meaning the same number of calories. This is what the macrobiotic diet did—better within days, and hitting normal fasting blood sugars within a week. 100% of those on the macrobiotic diet got down to at least under 110, whereas less than half of those on the diabetes diet did. And, this was on fewer drugs. In the control group, one person was able to reduce their oral hypoglycemic medications, whereas five of the seven on such drugs in the macrobiotic group had to stop taking them—otherwise their blood sugars would have fallen too low. So, better results on fewer drugs. That’s the power of a really healthy diet.

And, just as an aside, what a poke in the eye with a sharp stick this study was to the low-carb crowd. They took diabetics and put them on a 73% carbohydrate diet, adding a hundred grams of carbs to their daily diet, and in the form of grains. And what happened? Did their blood sugars skyrocket out of control? No, they got better—significantly better in a matter of days, with average fasting blood sugars starting out at 129, falling to 95, and, holy moly, their LDL cholesterol, down to 62, a nearly 48% drop, in three weeks.

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To see any graphs, charts, graphics, images or studies mentioned here, please go to the Nutrition Facts podcast landing page.  There, you’ll find all the detailed information you need – plus links to all the sources we cite for each of these topics.

Be sure to check out my new “How Not to Die Cookbook”. It’s beautifully designed, with more than 100 recipes for delicious and nutritious plant-based meals, snacks and beverages. All proceeds I receive from the sale of all my books go to charity.

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Thanks for listening to Nutrition Facts.  I’m your host, Dr. Michael Greger.

This is just an approximation of the audio content, contributed by Allyson Burnett.

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