The Science on Acai Berries

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An independent review of the effects of açaí berries was recently published, which included studies on immune function, arthritis, and metabolic parameters. The “Evidence-Based Systematic Review of Acai” was issued by the Natural Standards Research Collaboration (NSRC), an impartial scientific body that refuses to take support from product manufacturers. They are cited by the World Health Organization as one of the most authoritative sources on such matters. What did the NSRC find?

Whenever a new purported superfood hits the market, the first thing researchers tend to look at its chemistry such as antioxidant capacity, which was done back in 2006. Based on one measure of antioxidants, it had “the highest of any food reported to date,” — a remarkable finding I reported at the time in my video Antioxidant Content of 300 Foods. I’ve since unveiled Antioxidant Content of 3,139 Foods, and while acai’s title has been stripped, it’s still high in the list. Despite its cost, as I noted in Superfood Bargains, frozen acai pulp represents one of the best antioxidant bangs for our buck. We still didn’t know what it did outside of a test tube, though.

The next step is to go from test tube to petri dish and try it out on some human cells. They dripped the concentration of acai berry phytonutrients expected in one’s bloodstream after consumption on some cancer cells taken from a 36-year-old woman with leukemia. They saw a dramatic rise in cancer cell mortality–about twice that found previously using similar concentrations of hibiscus tea on the same cancer.

Acai was also found to boost immune cell function at extremely low doses. If you watch my 5-min video Clinical Studies on Acai Berries you can see actual footage of a human white blood cell gobbling up some invading yeast cells. Sprinkle some acai berry powder on them and they gobble more. With no acai for breakfast, white blood cells were able to engulf about 140 yeast, but in the presence of tiny amounts of acai they engulfed closer to 200. Slowly but surely researchers began piecing together the mechanism by which acai affected cellular function. Still, no human studies had yet appeared.

Researchers moved from cells to animal models. Who can forget the paper “Addition of Açaí to Cigarettes has a Protective Effect Against Emphysema in Mice” from my video Treating COPD With Diet? Instead of adding berries to their cigarettes, though, maybe mice shouldn’t be smoking.

Then, finally, starting in 2011, studies on actual people. The first paper, “Pain Reduction and Improvement in Range of Motion After Daily Consumption of an Acai,” studied about a dozen folks with painful conditions like osteoarthritis.  After 3 months, antioxidant levels went up, and pain levels went down. However, since there was no blinded control group drinking some kind of artificially acai-flavored Kool-Aid, placebo effects cannot be excluded.

The only other clinical study investigated the effects of açaí berries on metabolic parameters. Ten overweight folks were given two packs of frozen acai pulp every day for a month. Even though they were allowed to take it with sugar, their fasting blood sugars dropped, as well as their insulin levels and cholesterol. It appeared to significantly blunt the sugar spike caused by a standardized meal–all without any obvious adverse effects. In fact the only theoretical concern cited in the NSRC review was that it may work too well. If you’re on diabetic blood sugar lowering medications it could potentially drop your blood sugar too low, or if you have an autoimmune disease or are on immunosuppressants it could stimulate your immune system too much.

Caution: there was a case report of a guy whose muscles started dissolving after using an acai berry supplement. But it turns out there were no acai berries in it at all! That’s the problem with taking supplements; the industry is so poorly regulated you never know what you’re getting.

A study was done on 27 supplements of another purported superfruit, pomegranate.  Of the 27 tested only 5 appeared to be what the labels actually said. Fine, you say, no pills—you’ll just stick to the juice. Another study looked at 45 commercial pomegranate juice samples from 23 different manufacturers in the United States.  They each said 100% pomegranate juice on the label, but most of them lied. Only 6 out of 23 were what they said they were. The only source where you can be guaranteed to get authentic pomegranate juice has no label at all—the fruit itself!

I also have a video about pomegranate juice claims: Is Pomegranate Juice That Wonderful? And what’s true of pomegranate juice is true of other juices (Best Fruit Juice) with one exception (The Fruit Whose Juice Is Healthier).

Even if supplements contain what they say, they may not be useful (Dietary Supplement Snake Oil) and sometimes it’s what’s added rather than what’s missing that’s the problem (Some Ayurvedic Medicine Worse Than Lead Paint Exposure).

The beneficial effects of açaí berries do not appear to be unique. Indian gooseberries may also help control blood sugar (Amla Versus Diabetes) and rose hips may also help with arthritis (Dietary Osteoarthritis Treatment). In fact, plant-based diets in general may help metabolic parameters (Metabolic Syndrome and Plant-Based Diets) and arthritis (Diet & Rheumatoid Arthritis).

-Michael Greger, M.D.

PS: If you haven’t yet, you can subscribe to my videos for free by clicking here and watch my full 2012 – 2014 presentations Uprooting the Leading Causes of Death, More than an Apple a Day, and From Table to Able.

Image credit:  CostaPPPR/ Wikimedia Commons

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  • Kjell Ottesen

    Your antioxidant levels can be measured with a BioPhotonic Scanner. It measures your carotenoid levels in your skin. When adding supplements, or super foods, to your diet, you should check your levels as a “baseline” score first, and then re-scan after 60 days, the time it takes to see changes in your antioxidant levels. Then you will be able to identify if the antioxidant levels in your body increased. It is a tool I wish all doctors would offer in the practices!!

    • Nathan Ingram

      Which Biophotonic scanner are you referring to? Because I have one with the latest technological improvements.

      • Kjell Ottesen

        Hi Nathan!

        I have the Biophotonic scanner from Pharmanex. It measures the Carotenoid levels in your skin and is a marker for all antioxidants.

        • Nathan Ingram

          Hi there Kjell. I am familiar with that! It was featured on the Dr . OZ SHOW. The technology was developed by Dr. Gellerman. The scanner which was more recently developed measures carotenoids and flavonoids.

          • Kjell Ottesen

            Sounds like you are using the VIEW scanner which uses reflection spectroscopy compared to ours which uses Raman spectroscopy. I am just exited that you have the right tools so you can educate people about their antioxidant levels. It is one of the most important tests you can do with regards to your health and unfortunately most doctors are not aware of this. My GP calls herself a nutritionists but I had to educate her about antioxidants. She is now one of my customers!! Keep up the good work and never give up on educating the masses!

  • elsie blanche

    “In fact the only theoretical concern cited in the NSRC review was that it (acai berries) may work too well…. if you have an autoimmune disease or are on immunosuppressants it could stimulate your immune system too much.”

    Are you and/or this review suggesting that those with autoimmune diseases avoid acai berries? It sure sounds like it.

    • HappyPBD

      Great question! I am curious about the same thing.

      • elsie blanche

        Please ask Dr. Greger. He hasn’t gotten back to me on this but maybe if you and others ask he will respond.

        This is a serious issue as many with autoimmune diseases take acai berries, thinking it is good for them, when it might actually be causing harm. I really hope you do try to reach out to him. He left the ending of the video with a loaded statement that acai could stimulate your immune system too much – and I think that alone deserves its own video and bold headline. And please, share this statement in the video with those you know who have autoimmune disease.

  • Thea

    I *loved* this summary. Great overview of not just acai, but tying it in with info on supplements and juice. Nice.

  • Em Crone

    “Instead of adding berries to their cigarettes, though, maybe mice shouldn’t be smoking.”
    Haha that cracked me up!!! :)

  • Natalie

    Any recommendations of which acai berry pulp to purchase? And where? I want the good stuff! Thanks!

    • scudder

      Any answers to Natalie’s questions?
      Any recommended daily amount?

  • geoff

    Can anyone find the source for the study of most supposed 100% pomegranate juices being other than what they claimed? Curious which brands were honest.

    • http://www.vegannd.com/ Dr. Connie Sanchez, ND

      Foodfraud.org released info on pomegranate juice and other food frauds.

      http://www.nydailynews.com/life-style/health/food-fraud-alert-juices-oils-seafood-aren-article-1.1245843

      • geoff

        Thanks for the lead, nice to know about foodfraud.org

        Spending a little time trying to google up the relevant articles, the clearest answer I could find was Pom Wonderful being pure and 3 other juices (unnamed in the abstract) being adulterated. Guess I’ll be sticking with the expensive stuff for now

  • Agnieszka

    acai berry in the bottle order on line http://uk.monavie.com/rep/agam

  • Alsader

    I have a question. My mother is diagnosed with glioma in the brain. She is now a little bit weak. Can acai berries helps to fight cancer cells? Will my mother be able to regain her strength back? And we have no money for surgery. Thanks

  • AJW

    EmzaGold’s All natural Liquid vitamin / mineral supplement with 74 trace minerals, also has acai berry as one of its ingredients among many others. Very awesome product, and at a affordable price that does not break the bank. http://www.emzagold.com/aarongold