A single can of tuna causes as much mercury exposure as how many mercury-containing vaccines?
Mercury Exposure from Tuna vs. Thimerosal in Vaccines
Below is an approximation of this video’s audio content. To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video.
Once upon a time, routine childhood vaccinations used a preservative containing mercury called thimerosal. I was always surprised by parents who didn’t want to vaccinate their kids for fear of exposing them to mercury, yet went on to feed them tuna. Each thimerosal-containing shot would inject roughly the same amount of mercury that’s in a can of tuna fish. And while a child may only get a half dozen or so mercury-containing shots, they could be eating tuna salad sandwiches year after year. So, it’s evident that kids would be exposed to less mercury from vaccines than they would if they ate fish. Though when the mercury is injected, the absorption is like 100%, whereas if we just eat it some passes right through.
We used to think the gastrointestinal absorption of mercury was close to 100% following ingestion of the mercury in fish, though more updated estimates are consistently less than 100%. On the other hand, the form of mercury in fish is worse than the form of mercury used in vaccines, which is excreted from the body much more quickly. The mercury in fish represents the greater threat to children. But because any potential risk is of concern, in 1999 the Public Health Service, the American Academy of Pediatrics, and vaccine manufacturers agreed that thimerosal-containing vaccines should be removed as quickly as possible. And by 2001, thimerosal was removed from all vaccines in the recommended childhood immunization schedule.
Currently, in the United States, only multidose vial flu vaccines contain thimerosal, and thimerosal-free flu shots are widely available. Flumist, the nasal spray vaccine, is mercury-free, as well as most of the single dose vials used for pregnant women, which anyone can request.
Of course, thimerosal is still used in infants’ vaccines in developing countries. If the mercury load is deemed unacceptable in North America and Europe, why should it be given to infants in other parts of the world? We could also ask: if we want to play it safe and not expose kids to that much mercury, should we be feeding them fish, since kids are constantly getting that much mercury in their meals, and it’s methylmercury, which is even worse than the mercury in vaccines.
Now, there are ways to mitigate the mercury if you can’t beat some tuna craving. Drinking green tea with a meal may help block some of the absorption of mercury when eating fish. Normally, the recommendation is to not drink tea with meals, because it can also block the absorption of iron. But that’s better than the other way to protect yourself, shooting up with heroin. For some reason, the activation of opioid receptors protects nerves from mercury toxicity.
Please consider volunteering to help out on the site.
- Pichichero ME, Gentile A, Giglio N, et al. Mercury levels in newborns and infants after receipt of thimerosal-containing vaccines. Pediatrics. 2008;121(2):e208-214.
- Thimerosal and Vaccines. US FDA. Jan 15, 2025.
- Dórea JG, Farina M, Rocha JBT. Toxicity of ethylmercury (And thimerosal): a comparison with methylmercury. J Appl Toxicol. 2013;33(8):700-711.
- Benedict RT, Alman B, Scinicariello F, et al. Toxicological Profile for Mercury. Draft for Public Comment. CDC. Apr 2022.
- Bradley MA, Barst BD, Basu N. A review of mercury bioavailability in humans and fish. Int J Environ Res Public Health. 2017;14(2):169.
- Roy S, Aggarwal A, Dhangar G, Aneja A. Mercury in vaccines: A review. Glob Vaccines Immunol. 2016;2(1).
- Centers for Disease Control and Prevention (CDC). Thimerosal in vaccines: a joint statement of the american academy of pediatrics and the public health service. MMWR Morb Mortal Wkly Rep. 1999;48(26):563-565.
- Goldman LR, Shannon MW, American Academy of Pediatrics: Committee on Environmental Health. Technical report: mercury in the environment: implications for pediatricians. Pediatrics. 2001;108(1):197-205.
- DeStefano F, Bodenstab HM, Offit PA. Principal Controversies in Vaccine Safety in the United States. Clin Infect Dis. 2019;69(4):726-731.
- Thimerosal and Vaccines. US FDA. Jan 15, 2025.
- Dórea JG. Low-dose Thimerosal (Ethyl-mercury) is still used in infants` vaccines: Should we be concerned with this form of exposure? J Trace Elem Med Biol. 2018;49:134-139.
- Xue J, Zartarian VG, Liu SV, Geller AM. Methyl mercury exposure from fish consumption in vulnerable racial/ethnic populations: probabilistic SHEDS-Dietary model analyses using 1999-2006 NHANES and 1990-2002 TDS data. Sci Total Environ. 2012;414:373-379.
- Al-Sulaiti MM, Soubra L, Al-Ghouti MA. The causes and effects of mercury and methylmercury contamination in the marine environment: a review. Curr Pollution Rep. 2022;8(3):249-272.
- Jinadasa BKKK, Jayasinghe GDTM, Pohl P, Fowler SW. Mitigating the impact of mercury contaminants in fish and other seafood-A review. Mar Pollut Bull. 2021;171:112710.
- Anacleto P, Barbosa V, Alves RN, Maulvault AL, Bronze MR, Marques A. Green tea infusion reduces mercury bioaccessibility and dietary exposure from raw and cooked fish. Food Chem Toxicol. 2020;145:111717.
- Zijp IM, Korver O, Tijburg LB. Effect of tea and other dietary factors on iron absorption. Crit Rev Food Sci Nutr. 2000;40(5):371-398.
- Costa-Malaquias A, Almeida MB, Souza Monteiro JR, Macchi B de M, do Nascimento JLM, Crespo-Lopez ME. Morphine protects against methylmercury intoxication: a role for opioid receptors in oxidative stress? PLoS One. 2014;9(10):e110815.
Motion graphics by Avo Media
Below is an approximation of this video’s audio content. To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video.
Once upon a time, routine childhood vaccinations used a preservative containing mercury called thimerosal. I was always surprised by parents who didn’t want to vaccinate their kids for fear of exposing them to mercury, yet went on to feed them tuna. Each thimerosal-containing shot would inject roughly the same amount of mercury that’s in a can of tuna fish. And while a child may only get a half dozen or so mercury-containing shots, they could be eating tuna salad sandwiches year after year. So, it’s evident that kids would be exposed to less mercury from vaccines than they would if they ate fish. Though when the mercury is injected, the absorption is like 100%, whereas if we just eat it some passes right through.
We used to think the gastrointestinal absorption of mercury was close to 100% following ingestion of the mercury in fish, though more updated estimates are consistently less than 100%. On the other hand, the form of mercury in fish is worse than the form of mercury used in vaccines, which is excreted from the body much more quickly. The mercury in fish represents the greater threat to children. But because any potential risk is of concern, in 1999 the Public Health Service, the American Academy of Pediatrics, and vaccine manufacturers agreed that thimerosal-containing vaccines should be removed as quickly as possible. And by 2001, thimerosal was removed from all vaccines in the recommended childhood immunization schedule.
Currently, in the United States, only multidose vial flu vaccines contain thimerosal, and thimerosal-free flu shots are widely available. Flumist, the nasal spray vaccine, is mercury-free, as well as most of the single dose vials used for pregnant women, which anyone can request.
Of course, thimerosal is still used in infants’ vaccines in developing countries. If the mercury load is deemed unacceptable in North America and Europe, why should it be given to infants in other parts of the world? We could also ask: if we want to play it safe and not expose kids to that much mercury, should we be feeding them fish, since kids are constantly getting that much mercury in their meals, and it’s methylmercury, which is even worse than the mercury in vaccines.
Now, there are ways to mitigate the mercury if you can’t beat some tuna craving. Drinking green tea with a meal may help block some of the absorption of mercury when eating fish. Normally, the recommendation is to not drink tea with meals, because it can also block the absorption of iron. But that’s better than the other way to protect yourself, shooting up with heroin. For some reason, the activation of opioid receptors protects nerves from mercury toxicity.
Please consider volunteering to help out on the site.
- Pichichero ME, Gentile A, Giglio N, et al. Mercury levels in newborns and infants after receipt of thimerosal-containing vaccines. Pediatrics. 2008;121(2):e208-214.
- Thimerosal and Vaccines. US FDA. Jan 15, 2025.
- Dórea JG, Farina M, Rocha JBT. Toxicity of ethylmercury (And thimerosal): a comparison with methylmercury. J Appl Toxicol. 2013;33(8):700-711.
- Benedict RT, Alman B, Scinicariello F, et al. Toxicological Profile for Mercury. Draft for Public Comment. CDC. Apr 2022.
- Bradley MA, Barst BD, Basu N. A review of mercury bioavailability in humans and fish. Int J Environ Res Public Health. 2017;14(2):169.
- Roy S, Aggarwal A, Dhangar G, Aneja A. Mercury in vaccines: A review. Glob Vaccines Immunol. 2016;2(1).
- Centers for Disease Control and Prevention (CDC). Thimerosal in vaccines: a joint statement of the american academy of pediatrics and the public health service. MMWR Morb Mortal Wkly Rep. 1999;48(26):563-565.
- Goldman LR, Shannon MW, American Academy of Pediatrics: Committee on Environmental Health. Technical report: mercury in the environment: implications for pediatricians. Pediatrics. 2001;108(1):197-205.
- DeStefano F, Bodenstab HM, Offit PA. Principal Controversies in Vaccine Safety in the United States. Clin Infect Dis. 2019;69(4):726-731.
- Thimerosal and Vaccines. US FDA. Jan 15, 2025.
- Dórea JG. Low-dose Thimerosal (Ethyl-mercury) is still used in infants` vaccines: Should we be concerned with this form of exposure? J Trace Elem Med Biol. 2018;49:134-139.
- Xue J, Zartarian VG, Liu SV, Geller AM. Methyl mercury exposure from fish consumption in vulnerable racial/ethnic populations: probabilistic SHEDS-Dietary model analyses using 1999-2006 NHANES and 1990-2002 TDS data. Sci Total Environ. 2012;414:373-379.
- Al-Sulaiti MM, Soubra L, Al-Ghouti MA. The causes and effects of mercury and methylmercury contamination in the marine environment: a review. Curr Pollution Rep. 2022;8(3):249-272.
- Jinadasa BKKK, Jayasinghe GDTM, Pohl P, Fowler SW. Mitigating the impact of mercury contaminants in fish and other seafood-A review. Mar Pollut Bull. 2021;171:112710.
- Anacleto P, Barbosa V, Alves RN, Maulvault AL, Bronze MR, Marques A. Green tea infusion reduces mercury bioaccessibility and dietary exposure from raw and cooked fish. Food Chem Toxicol. 2020;145:111717.
- Zijp IM, Korver O, Tijburg LB. Effect of tea and other dietary factors on iron absorption. Crit Rev Food Sci Nutr. 2000;40(5):371-398.
- Costa-Malaquias A, Almeida MB, Souza Monteiro JR, Macchi B de M, do Nascimento JLM, Crespo-Lopez ME. Morphine protects against methylmercury intoxication: a role for opioid receptors in oxidative stress? PLoS One. 2014;9(10):e110815.
Motion graphics by Avo Media
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Mercury Exposure from Tuna vs. Thimerosal in Vaccines
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Content URLDoctor's Note
For videos on adult vaccines, check out:
- Benefits and Side Effects of the Shingles Vaccine
- Benefits and Side Effects of the Pneumonia Vaccine
- Benefits and Side Effects of the Flu Vaccine
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