Bovine casomorphin from cow’s milk is suspected to increase the risk of SIDS (sudden infant death syndrome, or crib death) based on the elevated blood levels in babies suffering acute life-threatening events, and their relative inability to clear it from their systems.
Cow’s Milk Casomorphin and Crib Death
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This report on cow’s milk-induced infant apnoea, thought due to the opiate-like effects of bovine casomorphin in milk, was just a single case report. It was so provocative, though, researchers immediately started testing other kids. SIDS, sudden infant death syndrome, also known as crib death, is the leading cause of death for healthy infants after one month of age. One in every 2,000 American babies die this way. Every day, six babies stop crying, and six parents start.
“Most susceptible…are infants exposed to several postnatal factors: sleep[ing on their stomach, secondhand smoke], and high sleep-room temperature. [But] it is supposed that in some cases of SIDS, it is cow’s milk that may play a certain role. It is also suspected that β-casomorphins hold a direct responsibility for that situation.”
“[Beta casomorphins] are biologically active,” with, as its name suggests, “effects similar to that of morphine. Penetration of β-casomorphins into the infant’s immature central nervous system may inhibit the respiratory centre in the brainstem leading to abnormal ventilatory responses, hypercapnia [which means too much carbon dioxide], hypoxia [not enough oxygen], apnoea and death.”
So, what they did was study infants who had recurrent life-threatening episodes—meaning apnoea, where they stop breathing, or turn blue, or become limp, etc. These are the kinds of events that place babies at high risk for SIDS.
The blood levels of bovine casomorphin in the babies with acute life-threatening events averaged three times higher than healthy babies. Why? Well, there’s an enzyme that gets rid of casomorphin, and the activity of that enzyme in the affected group was only half that of the healthy kids. So, some babies may just not be able to clear it out of their systems fast enough, and are placed at risk for death.
To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video. This is just an approximation of the audio contributed by veganmontreal.
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- Sun Z, Zhang Z, Wang X, Cade R, Elmir Z, Fregly M. Relation of beta-casomorphin to apnea in sudden infant death syndrome. Peptides. 2003 Jun;24(6):937-43.
- Wasilewska J, Kaczmarski M, Kostyra E, Iwan M. Cow's-milk-induced infant apnoea with increased serum content of bovine β-casomorphin-5. J Pediatr Gastroenterol Nutr. 2011 Jun;52(6):772-5.
This report on cow’s milk-induced infant apnoea, thought due to the opiate-like effects of bovine casomorphin in milk, was just a single case report. It was so provocative, though, researchers immediately started testing other kids. SIDS, sudden infant death syndrome, also known as crib death, is the leading cause of death for healthy infants after one month of age. One in every 2,000 American babies die this way. Every day, six babies stop crying, and six parents start.
“Most susceptible…are infants exposed to several postnatal factors: sleep[ing on their stomach, secondhand smoke], and high sleep-room temperature. [But] it is supposed that in some cases of SIDS, it is cow’s milk that may play a certain role. It is also suspected that β-casomorphins hold a direct responsibility for that situation.”
“[Beta casomorphins] are biologically active,” with, as its name suggests, “effects similar to that of morphine. Penetration of β-casomorphins into the infant’s immature central nervous system may inhibit the respiratory centre in the brainstem leading to abnormal ventilatory responses, hypercapnia [which means too much carbon dioxide], hypoxia [not enough oxygen], apnoea and death.”
So, what they did was study infants who had recurrent life-threatening episodes—meaning apnoea, where they stop breathing, or turn blue, or become limp, etc. These are the kinds of events that place babies at high risk for SIDS.
The blood levels of bovine casomorphin in the babies with acute life-threatening events averaged three times higher than healthy babies. Why? Well, there’s an enzyme that gets rid of casomorphin, and the activity of that enzyme in the affected group was only half that of the healthy kids. So, some babies may just not be able to clear it out of their systems fast enough, and are placed at risk for death.
To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video. This is just an approximation of the audio contributed by veganmontreal.
Please consider volunteering to help out on the site.
- Sun Z, Zhang Z, Wang X, Cade R, Elmir Z, Fregly M. Relation of beta-casomorphin to apnea in sudden infant death syndrome. Peptides. 2003 Jun;24(6):937-43.
- Wasilewska J, Kaczmarski M, Kostyra E, Iwan M. Cow's-milk-induced infant apnoea with increased serum content of bovine β-casomorphin-5. J Pediatr Gastroenterol Nutr. 2011 Jun;52(6):772-5.
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Cow’s Milk Casomorphin and Crib Death
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Content URLDoctor's Note
For an introduction to bovine casomorphin, see Cow’s Milk-Induced Infant Apnea. This three-part video series on the so-called “milk-apnea effect” concludes with a discussion of the role this morphine-like compound may play in other conditions, including autism, in Cow’s Milk Casomorphin and Autism. Casomorphins are also mentioned in my video, Is Milk and Mucus A Myth?
For additional context, check out my associated blog posts: Cow’s Milk Casomorphin, Crib Death, and Autism and Avoiding Dairy to Prevent Parkinson’s.
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