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DNA Protection from Broccoli

Eating broccoli appears to make DNA more resistant to damage.

March 9, 2012 |
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DNA Protection from Broccoli, 5.0 out of 5 based on 2 ratings

Sources Cited

Riso P, Martini D, Møller P, Loft S, Bonacina G, Moro M, Porrini M. DNA damage and repair activity after broccoli intake in young healthy smokers. Mutagenesis. 2010 Nov;25(6):595-602.

USDA Economic Research Service. U.S. per capita food availability: Individual vegetable: Broccoli.

Acknowledgements

Images thanks to ali graney, Biomedical Beat and Fir0002 via Wikimedia Commons.

Transcript

The best way to study DNA repair is to study smokers, because they need a lot of it. A group of smokers, for a total of ten days were asked to eat 6 times more broccoli than the average American consumes. In other words… a single stalk.
Compared to smokers not eating broccoli, those who did suffered about 30% less DNA damage over those 10 days. Maybe it was because the broccoli boosted the detoxifying enzymes in their livers and so the carcinogens never made it to their DNA?
Well they tested for that. They actually took some DNA out of their bodies, put it into a test tube and exposed it to a known DNA-damaging chemical. The DNA of broccoli eaters suffered significantly less damage; the DNA of those eating broccoli appears intrinsically was more resistant at a subcellular level.
In conclusion, in the present study, the intake of broccoli seems protective, as far as DNA damage is concerned, in smokers who are exposed to oxidative stress.

To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring watch the above video. This is just an approximation of the audio contributed by veganmontreal.

To help out on the site please email volunteer@nutritionfacts.org

Dr. Michael Greger

Doctor's Note

This discovery may help explain the findings I presented in Repairing DNA Damage. What about giving smokers kale? See yesterday's video Smoking Versus Kale Juice. There are 19 other videos about DNA damage and hundreds of other videos on more than a thousand subjects. And note that the sources for this video are all open access, so you can click on them above in the Sources Cited section and read them full-text for free.

For some context, please also check out my associated blog posts: Breast Cancer Stem Cells vs. Broccoli, Kiwi Fruit for Irritable Bowel Syndrome, and Is Caffeinated Tea Really Dehydrating?.

  • http://nutritionfacts.org/members/mgreger/ Michael Greger M.D.

    This discovery may help explain the findings I presented in Repairing DNA Damage. What about giving smokers kale? See yesterday’s video Smoking Versus Kale Juice. There are 19 other videos about DNA damage and hundreds of other videos on more than a thousand subjects. And note that the sources for this video are all open access, so you can click on them above in the Sources Cited section and read them full-text for free.

  • http://nutritionfacts.org/members/randy/ randy

    Thank you for the convenience and easy access to the articles, in the “sources cited”.

    Terrific job, thank you.

  • http://nutritionfacts.org/members/virre-vojj/ Virre Vojj

    Hello there! Just wanted to say thanks for all the great videos. I’ve been a follower of your nutritionfacts for many months as well as reading your articles on oneegreenplanet. It’s such a great resource for me on research in my diet and you’ve managed to put everything together in a very easily understandable way. Now if I could just find some of that amla for my morning smoothies..

  • http://nutritionfacts.org/members/valnaples/ valnaples

    Hi, Dr. Greger: LOVE your videos…are the florets the best bet or should we be eating stalks/stems AND florets? Have been reading up on the sulforaphane but haven’t seen anything specific about which part of the plant this is found in. Thank you!

  • Michael Greger M.D.

    For some context, please also check out my associated blog post Breast Cancer Stem Cells vs. Broccoli!

  • http://www.facebook.com/anthony.lorenzo.140 Anthony Lorenzo

    One should cook broccoli lightly before eating it… to get the full nutritional benefits!

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