Doctor's Note

Sadly, Americans are Living Longer but Sicker Lives. How do we lower the activity of the aging enzyme without caloric restriction? My follow-up video Caloric Restriction vs. Animal Protein Restriction will be up on Monday. If, however, you can't wait, the next 24 videos going through to June are available on my latest DVD (all proceeds to charity) that is available for instant download.

I discuss the “rusting” theory of aging in my video Mitochondrial Theory of Aging and have an older video on Research Into Reversing Aging.

More tips for preserving youthful health:

If you haven't yet, you can subscribe to my videos for free by clicking here.

To post comments or questions into our discussion board, first log into Disqus with your account or with one of the accepted social media logins. Click on Login to choose a login method. Click here for help.

  • HemoDynamic, M.D.

    I have to wait until tomorrow?
    Comon I’m dying here.

    • Gah!!! A weekend cliffhanger!!

    • Thea

      Oh HemoDynamic: You literally made me laugh out loud. Too funny.

      • Laloofah

        Cracked me up, too! And bonus points for the Easter Island statue head emoticon! :-D

        • Thea

          Laloofah: re: emoticon. I missed that! Good catch. Thanks.

        • HemoDynamic, M.D.

          interestingly the emoticon I can see on my iPhone but not my Windows Computer.

          • Laloofah

            It (and below, your death-dealing devil) show up on both my iPad & my iMac, showing their superiority yet again to Windows PCs. (But then, you probably don’t want to get another Apple since they keep the doctor away!) ;-)

          • JacquieRN

            Love it Laloofah!

          • Laloofah

            LOL, my plug for Apple or my plug for apples? Or both? :-)

          • Probably because Emoji is a type of font you haven’t got installed on your PC?

    • Dee

      He’s going to talk about intermittent fasting.

      • HemoDynamic, M.D.

        Spoiler alert! You might be able to Juke it but you can’t cheat death!

    • Plantstrongdoc M.D.

      Michael Greger is the master of health – and the master of suspense!

  • Craig

    My guess… Water fasting. The benefits of water fasting are becoming increasingly more recognized and important. Some individuals can go months and even a year without eating. Of course variables come into play. But this may be a valuable life extension therapy for some extremely sick and/or overweight individuals.

    • Psych MD

      A year w/o eating? Sounds like something one of my schizophrenics would say. I, too, anticipate the answer will be intermittent fasting. Eating every other day, as studied in the above-referenced article, is ridiculous since no one can follow such a protocol for any length of time. I have been practicing a simple, totally doable form of IF for about a year. Basically I skip breakfast, drinking copious amounts of lemonized green tea, Indian spice black tea, and citrus-hibiscus tea, courtesy of our office Celestial Seasoning K-cups while doing my morning rounds. My work distracts me from the minor feelings of hunger until noon, at which time I sit back and relax with some mixed nuts, celery and carrot sticks, sliced apples and hummus and watch Dr. Greger’s latest video. It’s one of the highlights of my day, followed by driving home in my Mustang.

      • Psych MD

        The process is hormesis: essentially what doesn’t kill you makes you stronger. Put another way-long term stress is harmful but short term stress is beneficial. Our society, with a limitless supply of cheap, easily accessible food has eliminated any semblance of stress with respect to hunger.

      • b00mer

        I started a similar habit this past year. I only consume my (white) tea with lemon in the morning, which if I’m honest is really the only thing I’m interested in when I wake up. I don’t eat breakfast right away, but rather I bring it with me to work, and eat it whenever I get hungry, sometimes 10am, sometimes noon. I don’t feel like I’m depriving myself, but I like that I’m not forcing myself to eat when I’m not really hungry either. And if I get any IF benefits, that’s gravy.

      • Craig

        Here is an interesting article on water fasting from the T. Colin Campbell center for nutrition studies which explains the length of time someone, depending upon dietary factors can be on a water fasting diet.

        Also all an vegan diet can slow the aging process as Dr. Dean Ornish has proved in research.

        Below is a link to water fasting. Enjoy the article.

    • Julot Julott

      30-100 days without food is possible depending of the person~

      • Found this article about Joel Fuhrman, mentioned his experience fasting:

        When the U.S. Olympic Committee’s orthopedist urged Fuhrman to undergo an experimental surgical procedure for his heel, Fuhrman refused. He sought treatment instead from Herbert Shelton, a San Antonio naturopath who specialized in irregular cures. Fuhrman, a fit 150 pounds, was put on a regimen of only water for 46 days. “They nearly killed me,” he says. “I fasted down to 88 pounds.” His heel trouble vanished, but so did most of his muscle, and he was unable to regain top form in time for the 1976 Olympics.

        I’d say 100 days is a bit far-fetched.

  • Steve


  • ChristineMo

    OH these cliffhangers!!! Should I eat breakfast or just fast?!? eat, or fast?; or just eat fast? Tell Us!!

    • Hector Navata

      June 6, 2012 Chronological Age: 72; Biological Age: 50; Vascular Age: 44

  • ChristineMo

    Throw us a bone, already. Oh, right…

  • Kathie

    Would you comment on the article that was just published in PLOSone which concluded that “a vegetarian diet is associated with poorer health …, a higher need for health care, and poorer quality of life”? Burkert NT, Muckenhuber J, Großschädl F, Rásky É, Freidl W (2014) Nutrition and Health – The Association between Eating Behavior and Various Health Parameters: A Matched Sample Study. PLoS ONE 9(2): e88278. doi:10.1371/journal.pone.0088278

    • Pat B

      In the discussion they stated “…no statements can be made whether the poorer health in vegetarians in
      our study is caused by their dietary habit or if they consume this form
      of diet due to their poorer health status. We cannot state whether a
      causal relationship exists…”

      Seems they should’ve mentioned that in their conclusions too.

    • JacquieRN

      Note from Dr.Garth Davis:

      “Social media, and its infinite viral wisdom, strikes again. A ridiculously bad article was published in an online crappy journal and it is now spreading like wildfire as if it is the truth handed down by God.

      The article states that vegetarians are less healthy than meat eaters. What?! There has never been a study that has been so bold as to state such a fact! They must have something big, right? I mean this goes against the vast majority of recent science. Anytime an article is an outlier it needs to be well understood, and for it to have meaning it should be replicated. So lets take a look.

      This study is from Austria. They looked at over 15,000 people. So since this is a comparative study I would imagine there must be quiet a few vegetarians right? WRONG!!!! 0.2% where vegetarian. That is it. A few measly vegetarians. With such a low amount there is no way that you can do an adequately powered statistical analysis, so the authors didn’t try. Instead they matched the few vegetarians they had with age matched meat eaters. Some of the vegetarians had no age matched counterparts so they were dropped from the study!!!!! Even fewer vegetarians now.

      OK so we are going to take these few vegetarians and compare them with meat eaters and follow them for years and see how the do, right? WRONG!!!!! They just did one interview with them to assess their health and their eating habits. So do we know how long they have been vegetarian? No. Could they have turned vegetarian because they were sick. Of course. Many people facing a diagnosis of heart disease turn to vegetarian diet. In this case the heart disease would have been equated with being vegetarian. This was a 1 day study not a multiple year prospective study like the Adventist Health Study.

      Well at least we should be able to discern exactly what “vegetarian ” means, right? We should at least know that these vegetarians are in fact eating vegetables, right? Wrong! They applied labels on people but never assessed their exact meal plan. There is no mention as to how many fruits and veggies they were eating. In fact, they noted that the vegetarians were less likely to pursue preventative health, which in itself could explain their poor health. What this means is that these people were unlikely vegetarian for health reasons. In predominately meat eating populations when you find very few people abstaining from meat, and not going in for regular doctors visits, it could be that they are “ethical” vegetarians. In other words, they do not eat meat because of the cruelty aspect. Often times these people eat quite a junk food diet. Lots of processed carbs and not much actual fruit and veggies.

      In the end this is just bad science. Their conclusion is not worth the paper this would have been printed on had it actually been printed. Instead this wound up on an online journal known for poor peer review. This was not debated at a large scientific conference. This study would have gotten F had a student turned it into me, regardless of the findings, just based on the poor experimental design. In the end, this study would have been never looked at again, except that social media loves a good controversial study that confirms what everybody wants to believe. Now it is showing up all over the internet as if Harvard had just released the study in The New England Journal of Medicine. And this is why people get so confused!”

      • Ernest Mayberry


        Excellent response!

      • Leo

        The correlation between high school grades and aptitude as a researcher is sometimes not very high.

        I am 75 and have been a vegetarian for 61 years, varied vegetarian / vegan / rawfoodist.

        I made ​​my transition “cold turkey” to a lacto-vegetarian rawfood in 1953. I even made my military service as lacto-vegetarian rawfoodist according to contemporary standards.

        Now I’m mostly high raw vegan. I can’t imagine a better life style.

        My only medical problem since I became a vegetarian has been all regular colds,
        one in 1968,
        one in 1988
        and the last in 2010.

      • ChristineMo

        This is the terribly frustrating thing about the information-proliferation society–it seems that–barring expect ability to decode research methods (and a willingness to do that heavy-lifting) the more we know, the less we know: most folks are at the mercy of a strangely powerful conceit that “lies wouldn’t be printed.” Only specialists know that not all journals are created equal etc!!!

        • Veganrunner

          And even the best of journals publish bad articles. I just reviewed a Cochrane meta that was so poorly done it shocked me.

      • HemoDynamic, M.D.

        Welcome to the Team!

  • Rick Stewart

    m-Tor pathway! It was thought that calorie restriction was the key to longevity, when in effect, eating less food naturally provided less of a particular amino acid that speeds aging. So by eating less protein, we restrict that particular amino acid (who’s name escapes me) and we live longer. No need for caloric restriction to enhance longevity. Just eat less protein! ;)

  • slpphd

    Intermittent fasting???

  • guest

    I looked into taking rapamycin so I’d age slower, but I found out that it shuts down your immune system, so you’d better live in a germ-free bubble if you’re going to take it. I also found out that it’s the same stuff they give organ transplant patients so their bodies don’t reject the new organs. Wonder how they avoid dying when they catch a cold.

  • guest2

    Is this aging phenomenon because mTOR forces cells to divide more frequently, so that they reach their Hayflick limit earlier, resulting in senescence?

  • Arjan den Hollander.

    I’m betting resveratrol!

  • DGH

    I don’t eat any animal products. What I would like to know is what is the role of omega-6-rich foods for a plant-based diet, specifically things like nuts, seeds and their derivatives (oils and seed butters)? Many whole foods people seem to avoid them like the plague but more moderate vegan nutritionists state that their health effects are way overblown. And what about avocado, which is rich in monounsaturated fatty acids? I like a moderate amount of fat in my diet (all plant-based), consuming tahini, nuts, seeds, guacamole. Am I harming my future coronary health? I wish there were some hard data/evidence on this. Everyone has a conflicting opinion – Esselstyn, Fuhrman, Jenkins, etc.

    • b00mer

      I don’t think there is as much conflict between the actual “experts” as there is among the people that follow them. Esselstyn and McDougall both say that objectively, an ounce of nuts or seeds per day is fine (barring active/advanced heart disease). But since they feel that some people have a hard time limiting themselves to a particular serving size, they skew the message and end up saying that perhaps it’s better to just avoid them. But then many of their followers interpret this as nuts, seeds, and avocado are off-limits and to be absolutely avoided

      I also think their stance may be a sort of backlash against the prevalent fetishizing of “healthy fats” in the sense that people think that [non-omega-3] fats are something that they need to put effort into increasing the levels of in their diet. When like the other macronutrients, particular fat levels are not something that need to be strived for.

      [I know that you DH have said that you consume a lower-carb diet and so I recognize that some people do have particular macronutrient goals, but generally in the WFPB world, the message is that micronutrients density is more of a focus than macronutrient ratios.]

      Novick recommends 1-2 servings per day, here is a sample menu where he lists that a couple ounces of nuts/seeds per day, or an ounce of nuts/seeds plus half an avocado is fine per Engine 2 diet recommendations.

      The nuance lies in Esselstyn and McDougall saying that a one ounce serving per day is fine, but also sending the message that you’re fine if you don’t eat any. Furhman’s message is slightly different. He recommends 1 oz per day but claims that you are better off eating them than not.

      On to the others, we all know Dr. Greger recommends 1-2 oz nuts/seeds per day, and Dr. Barnard also recommends 1 oz per day; whether his recommendation is more of a condonation with a limit a la Esselstyn/McDougall or an emphatic recommendation to intentionally consume them for certain micronutrients ala Furhman/Greger, I’m unsure.

      But in the end I think these nuances in recommendations are not worth the debate they inspire! Across the board, 1-2 servings per day of nuts/seeds/avocado is either emphatically recommended or at least condoned.

      However everything I’ve written has been in the context of examining caloric density and micronutrient density (vitamins, minerals, phytosterols, other phytonutrients, and omega-3 FAs), i.e. we’re talking about high-fat whole foods.

      In terms of recommending MUFAs themselves for certain health benefits (i.e. consuming oils), the only concrete evidence I’ve seen for intentional consumption is in the context of using them to *replace* saturated or trans fats. In fact even the fine print on the back of my bottle of canola oil (right below the huge “Heart Healthy!” banner) states:

      “Limited and not conclusive scientific evidence suggests that [canola oil] may reduce the risk of coronary heart disesase due to the unsaturated fat content. To achieve this possible benefit, canola oil is to replace a similar amount of saturated fat and not increase the total number of calories you eat in a day.”

      So it’s better than lard or butter, but that’s not the best rationale for consuming something in my opinion.

      • DGH

        b00mer, thank you for that lovely summary of their approach. I realize that more and more experts even in the vegan community are recommending nuts, seeds, etc, but I think there is one camp that says that vegetable oils, seed butters and nut butters are ok (in moderation), and another says that they are not, because there are highly processed, calorie-dense food that has been stripped of micronutrients and food matrix (e.g. fiber). In other words, because vegetable oils and nut/seed butters are not a whole food, they are not an acceptable addition to the diet. I find it difficult to completely eliminate seed butters from my diet and I crush/grind nuts/seeds anyway, so I am getting effectively the same thing in my smoothies. I do not use any vegetable oil because I find this is very easy to avoid.

        • b00mer

          Well across the board it seems people disagree with consuming oils, as they have no micronutrient value. Some people may “allow” them in moderation, but some people allow refined sugar/syrup in moderation too. Joel Furhman allows 10% of the diet to be animal products and refined plant products. Allowing doesn’t make much of an impression to me as to whether I should have it in my diet.

          When I have read certain people saying a little oil is fine (maybe it was Ginny Messina or another vegan RD?), it seemed like it was coming from this perspective that the “no-oil” movement was scary and restrictive and they wanted to counteract that so that people wouldn’t be frightened to try going plant-based. Perhaps they still enjoy oil themselves and want to discount “no-oil” as extreme and irrational.

          But seed butters I haven’t heard so much about. I would think anyone who allows 1 oz nuts/seeds would allow the equivalent (a couple hundred?) calories of nut butter?

          Of course everyone prefers whole over ground of any food type, but if this is one of the foods that are eaten sparingly, I personally just don’t think it’s something to worry about. Unless you have specific health issues that you want to remedy, in which case, just perform a month or two long experiment and see if anything happens.

          As much as Esselstyn, Novick, and McDougall tend to rail against nuts, and are always saying to choose other foods over nuts, that does not translate to “don’t eat any nuts ever”. It means out of the dozens of servings of food per day that you’re eating, make sure that for most except for one or two, you’re choosing other foods over nuts.

          Though since you bring up smoothies, that does reminds me of Esselstyn coming out against them (though more for the blood sugar effects of high-fruit smoothies). But then, I think there is a significant difference between a greens-heavy, low-sugar (some citrus or a few berries) smoothie, and some of the ones you see where it’s just a token handful of spinach and then several whole fruit. When these experts come out against something carte blanche, I think some important considerations and nuances get lost in the message.

          Do you have any links or names for anti-nut-butters?

          • DGH

            Hi b00mer, I do not have any links or names for anti-nut-butters – but I have seen on the internet people saying no peanut butter or other butters, even unroasted.

            Note that extra virgin olive oil does have some evidence to support it, despite its high calorie density. It does seem to have beneficial antioxidants in it, even setting the aside the issue of monounsaturated fats possibly being healthy in fat and/or glucose-insulin metabolism. However, I would use any in strict moderation, because it is very calorie-dense.

            My morning smoothie contains 1/4 cup blueberries, 1/2 cup beans, flaxseed, hempseed, nuts, pumpkin seeds, almond milk, cocoa powder, wheat germ and wheat bran. On the side I eat a large carrot for vitamin A. This keeps me full for 6-7 hours. Of course I could take out the nuts and replace them with more beans but then 1) I will be less satiated; 2) I will be getting a higher glycemic load (and given my tendency towards metabolic syndrome, I don’t want to go back towards that).

            I am not saying that nuts are good for health in order to justify my diet; I am simply saying I would have a hard time finding a filling breakfast smoothie without them (by the way I am allergic to kale and possibly closely related plants).

            Nuts are lower in saturated fat than meat, have no trans fats or cholesterol, do not contain polyaromatic hydrocarbons or acrylamide from high-temperature cooking, and are typically high in more benign MUFA and omega-3 PUFA. PREDIMED suggests they are beneficial, at least in replacing other foods commonly eaten. I would still consume them in moderation because of their high caloric load and I have stopped snacking on them entirely. For more on the benefits of nuts, this article, which is unfortunately behind a paywall, is interesting:

  • NZBoomer

    Life expectancy in London was not less than 16 years old. You have used the average age of death which includes all the babies and children who did not reach adulthood due to illness,malnutrition, accident etc. This skews the results. After reaching adulthood the life expectancy was much higher. After all even a 2000+ year old book says we get 3 score years and 10! In the middle ages if a person reached age 21 they could expect on average to live to age 64.

    • masobel

      You are correct, however this is how life expectancy is typically calculated. High infant and childhood mortality lowers the overall life expectancy of a population. There were some pretty significant public health issues in London in this time period.

  • We read Dr Greger’s work here every morning. And we think it’s no mystery! It’s just a WFPB diet.

  • Gayle Delaney

    Oh what a TEASE! We have been following the 5:2 Fast regime of 4-700 cal per day for 2 days a week and eating a la Greger and Fuhrman for 7 months. We would love to hear of another, easier way to promote autophagy and perhaps neurogenisis as seen in rats. Can’t wait for tomorrow! ( Michael Mosley’s 5:2 diet described here:

    • Blanster

      Gayle, how is that working for you? I have the Fast book, I just haven’t tried it yet.

      • Gayle Delaney

        Hi Blanster,
        Well… when we eat the 400 cal and Kevin the 700 cal (male/female suggested) diet, we have trouble sleeping, not so much for feelings of hunger, but for a sort of agitation in our veins, a sort of vibration that is bothersome and shortens sleep times and sleep pleasure. In the last couple of months we have upped the cals a bit.
        I wonder if 2 days a week of reduced intake of healthy WF is a long-term problem.
        And we do feel deprived and hungry. SO, I would like to know if it is worth it. When we eat our normal Greger/Fuhrman diet we are in heaven. First time since my early teens that I am not hungry every single day trying to maintain my 103 lb weight!
        Moseley’s BBC-TV show really inspired us, the book less so. And of course, Mosely’s regular, non-fasting days diet is a bit of a nightmare.

        • Arjan den Hollander.

          Probably cortisol that you are feeling the effects of.

          Hypoglycemia triggering cortisol then raises your glucose, heart rate.

          That is what makes you feel edgy.

        • Blanster

          Thanks for the info! That certainly sounds problematic. I hope you can find something that works and feels good, although it sounds like the Fuhrman/Gregor diet works pretty well for you!

    • Arjan den Hollander.

      Don’t you fast every night while you sleep?
      If that is not standard I’m sure with a very slight modification to food intake times the same can be achieved without the suffering :)
      Say eat @ 17:00 and nothing after.

      And isn’t it just asking for radical damage during off hours?

      • Gayle Delaney

        Thank you, Arjan for your video reference. During our very low cal days we eat very high nutrient snack (sprouts, pink juice, super tomato soup with all the healthy spices, basil,onions garlic…) I wonder if the daily skipping of breakfast would be as promoting of autophagy and possible neurogenisis. It is much more appealing and we often do this without thinking of it.

  • BennyB

    $1,000 dollars says the answer is: a whole foods, plant based diet!

    • Arjan den Hollander.

      Sometimes to much repetition is counter productive!

      Without reading the question $1000 dollars says the answer is:
      A whole foods plant based diet!

      LOL, hehehe.

      • Gayle Delaney

        When Dr. G repeats this conclusion I know he is giggling inside so I don’t mind. And it is the truth, so he must say it. AND he almost always adds to our knowledge about the benefits of WFPB diets. Thus, he strengthens my resolve.

    • Timar

      Sure, this is why vegans are immortal…

      • Arjan den Hollander.

        If only they could defend themselves they’d rule the world!


  • Darryl

    A strong contender as one reason (of several) we age, at any rate. For those curious about Mikhail Blaggosklonny’s hyperfunction theory (aging is caused by overactivity in adulthood of developmental processes important during growth), i found this recent review offered more clarity than Blaggosklonny’s own papers, as well as a fair introduction to a major strand in experimental gerontology for the past decade:

    Gems, David, and Linda Partridge. “Genetics of longevity in model organisms: debates and paradigm shifts.” Annual review of physiology 75 (2013): 621-644.

    • bob

      MAYBE…if you are 67.4 years or older…the following is true?

      They designed a study to investigate the relationship between protein intake and future decline in higher-level functional capacity in older community-dwelling adults in Japan. Their analysis included 1,007 individuals with an average age of 67.4 years who completed food questionnaires at the start of the study and seven years later.

      Participants were divided into four groups (quartiles) according to
      their intake levels of total, animal, and plant protein. Tests of
      higher-level functional capacity included social and intellectual
      aspects as well as measures related to activities of daily living.

      Men in the highest quartile of animal protein intake had a 39 percent decreased chance of experiencing higher-level functional decline than those in the lowest quartile. These associations were not seen in women.

      No consistent association was observed between plant protein intake and future higher-level functional decline in either sex.

      • Gayle Delaney

        Hmmm. Any more comments on this? If true, why the effect in men and not women?

        • bob

          Since I fit this demographic…I’m definitely interested in some discussion. It is antagonistic to the theme of the videos to some extent. Personally I consume mostly salmon and lean beef….usually 2-4 oz per home cooked meal…along with a variety of vegs…beans…nuts…some dairy…MCT oil (coconut)and olive oil. Seem to need or want the animal protein….not sure whether from habit or actual need.

          • J.

            Neither of those oils are good for you and aren’t only “MCTs” and shouldn’t be considered “MCT oil” that is completely wrong. lol. Meat is full of endotoxins and other poisons.

  • Julot Julott

    You are not starving at all when you completely water fasting after 2-3 days instead calories restriction~

  • Sue

    Love the opening photo–beautiful baby and great grandma.

  • artcomm

    I’m extremely worried about this: – why are they trying to confuse people so badly?

  • Cameron

    Despite solid research showing that calorie restriction extends life in nematodes and mice, CR in primates doesn’t seem to extend life, but may be helpful to maintain health.

  • Zuppkko

    Any kind of fasting is good, but juice fasting (up to 30 ounces a day) with additional GI tract cleanse (enemasm colonics, herbs) seems to work best.

  • five_aggregates

    We age because we are born…

  • Anton

    I have a question for Dr. Greger (by the way, thank you very much for all you do – i sincerely appreciate your work). I’m hoping Dr. Greger will include it in his Q&A soon. I work as a nutrition manager in a long-term care facility in Canada. I’ve been following your work for a little while and I myself eat a plant-based diet. In my facility, however, menus are extremely unhealthy – we have eggs every day for breakfast (there’s often an omelet or an egg salad as one of the choices at lunch, too), milk at every meal and snack, lots of cheese, meat, fish and sweets. Out budget is $7.92 a day in Ontario. I was wondering what your opinion is on whether it is possible for elderly people to thrive on a plant-based diet (many doctors and RDs I know will not embrace this idea). Also, do you think it’s possible to provide adequate plant based nutrition on such a limited budget? Finally, how do you think we can get their buy-in? I’ve also been thinking that it would be kinda cool to do a study – have a few elderly people switch to a vegan diet, and follow their progress for a while. We have all their health data going back months and years! =)
    Thanks a lot!

    • Tommasina

      Anton, What a great question, and how lucky for your residents to have you looking out for them! I would direct you to this great cost-comparison Dr. Greger did on plant-based diets versus a standard diet: .

      Regarding elderly people on a plant-based diet, Dr. Greger has a great video on this but it won’t be released for a little while (it’s the last video on his newest DVD, volume 18). I’ll give you this teaser:

      “Women in their 70s with the
      most carotenoid phytonutrients [from eating fruits and vegetables] in their bloodstream were twice as likely to
      survive five years than those with the lowest.”

      There’s also a new book on WFPB diets for those over 50 with a chapter on eating in long term care facilities: I haven’t read it but I heard a great interview with Ginny Messina, one of the authors. You might want to check it out.

      These are tangentially related:
      How to slow brain aging:
      Nuts may help prevent death
      Increased lifespan from beans

      I’m hoping healthier residents with increased lifespan is something most facilities for the elderly would find worthwhile, and not a cost to be avoided. Anyways, good luck!

      • Anton

        Thanks for your response. It was great. I know about Ginny Messina, she runs – i think she’s great. I’ll probably buy and read her book in the near future.

    • Thea

      Anton: Thanks so much for this post. It’s heartening to see that someone is trying look out for the older folks in our community. To round out Tommasina’s excellent reply, I thought I would let you know that the well-researched group, Vegetarian Resource Group (VRG) produced two magazines with articles on this very topic.

      Volume XXXI, NO 4: “Accommodating Vegans in Assisted-Living Settings” – “Chef Nancy Berkoff, RD, EdD, helps you cater to vegetarian clients in this latest Foodservice Update.”

      Volume XXXII, NO 3: “Vegan Menus For Adults 51+” – “Christine Kasum Sexton, MPH, created menus in a range of calorie counts, including low-income options.”

      Maybe you could get a copy of these issues/articles? There may be other articles too that are helpful. These are just the ones I know about.

      I think we are on the verge of really helping our seniors. People like you will be leading the way, difficult as it may be. Best of luck to you!!!!

      FYI: Website where I think you can learn more about VRG:

      • Anton

        Thanks for the info!

  • Lawrence

    Dr. Greger,

    Pursuant to a recreational study of biochemistry to better appreciate my WFPBD, I have encountered an unfamiliar disaccharide of glucose known as trehalose that is suitable for human glycolysis (Lehninger, 2nd ed, pg 424). Curious, I researched this molecule and found this study that shows trehalose to be ‘an mTOR-independent autophagy activator’ and to confer some protection against Huntington and Parkinson disease. Question: is trehalose something we should start sprinkling on our morning oatmeal to enhance the effects of our plant-based leucine-restricted diets, or is this much ado about nothing? Thank you.

  • Kamen

    Where is the next video?

  • Fmnt

    So how can I enhance (Leucine and HMB mediated) muscle grow without aging fast?

  • Davide Callegari

    TOR sounds very much like IGF-1 hormone

  • alio loco

    About two months ago (before discovering
    and buying “How Not to Die”) I started taking a supplement named Basis.
    Basis is manufactured by a company known as Elysium Health, LLC. The
    company’s website is
    Basis is marketed as an anti-aging supplement. According to an
    article in “MIT Technology Review” by Karen Weintraub, dated Feb., 2,
    2015, Basis contains a chemical precursor, nicotinamide riboside, to
    nicotinamide adenine dinucleotide, or NAD. NAD is a compound that cells
    use to carry out metabolic reactions like releasing energy from glucose.
    The compound is believed to cause some effects similar to a diet that
    is severely short on calories—a proven way to make a mouse live longer.
    Elysium claims that the human body can transform nicotinamide riboside
    into NAD and use it. Basis also contains pterostilbene, an antioxidant
    that Elysium’s founders say stimulates sirtuins in a different way. I AM
    SURE I AM NOT THE ONLY PERSON TAKING BASIS. So, I believe the community
    would benefit from Dr. Gregor’s thoughts about this supplement. I am
    paying $50.00 a month for Basis. I AM PARTICULARLY INTERESTED TO KNOW IF

  • alioloco

    About two months ago (before discovering
    and buying “How Not to Die”) I started taking a supplement named Basis.
    Basis is manufactured by a company known as Elysium Health, LLC. The
    company’s website is
    Basis is marketed as an anti-aging supplement. According to an
    article in “MIT Technology Review” by Karen Weintraub, dated Feb., 2,
    2015, Basis contains a chemical precursor, nicotinamide riboside, to
    nicotinamide adenine dinucleotide, or NAD. NAD is a compound that cells
    use to carry out metabolic reactions like releasing energy from glucose.
    The compound is believed to cause some effects similar to a diet that
    is severely short on calories—a proven way to make a mouse live longer.
    Elysium claims that the human body can transform nicotinamide riboside
    into NAD and use it. Basis also contains pterostilbene, an antioxidant
    that Elysium’s founders say stimulates sirtuins in a different way. I AM
    SURE I AM NOT THE ONLY PERSON TAKING BASIS. So, I believe the community
    would benefit from Dr. Gregor’s thoughts about this supplement. I am
    paying $50.00 a month for Basis. I AM PARTICULARLY INTERESTED TO KNOW IF

  • Darryl

    The Nobel Assembly at Karolinska Institutet has today decided to award
    the 2016 Nobel Prize in Physiology or Medicine
    Yoshinori Ohsumi
    for his discoveries of mechanisms for autophagy
    This is important stuff that your kids will learn in HS.