Image Credit: Misky / Unsplash. This image has been modified.

Garlic Powder to Lower Lead Levels

There are so-called chelation drugs that can be taken for acute, life-threatening lead poisoning—for instance if your two-year-old swallowed one of the little lead weights her grandma was using while sewing curtains and the doctor happened to miss it on x-ray, so it stayed lodged inside her until she died with a blood lead level of 283 mcg/dcl, a case I discuss in my video Best Foods for Lead Poisoning: Chlorella, Cilantro, Tomatoes, Moringa?.

However, for lower grade, chronic lead poisoning, such as at levels under 45 μg/dL, there were no clear guidance as to whether these chelation drugs were effective. When they were put to the test, the drugs failed to bring down lead levels long term. Even when they worked initially, in dose after dose, the lead apparently continued to seep from the patients’ bones, and, by the end of the year, they ended up with the same lead levels as the sugar pill placebo group, as you can see at 0:50 in my video. It was no surprise, then, that even though blood lead levels dipped at the beginning, researchers found no improvements in cognitive function or development.

Since much of lead poisoning is preventable and the drugs don’t seem to work in most cases, that just underscores the need “to protect children from exposure to lead in the first place.” Despite the medical profession’s “best intentions to do something to help these kids…drug therapy is not the answer.” Yes, we need to redouble efforts to prevent lead poisoning in the first place, but what can we do for the kids who’ve already been exposed?

The currently approved method, these chelating drugs that bind and remove lead from our tissues, “lack[s]…safety and efficacy when conventional chelating agents are used.” So, what about dietary approaches? Plants produce phytochelatins. All higher plants possess the capacity to synthesize compounds that bind up heavy metals to protect themselves from the harmful effects, so what if we ate the plants? “Unlike other forms of treatment (e.g., pharmacotherapy with drugs), nutritional strategies carry the promise of a natural form of therapy that would presumably be cheap and with few to no side effects.” Yes, but would it work when the drugs didn’t?

We had learned that a meal could considerably cut down on lead absorption, but “the particular components of food intake that so dramatically reduce lead absorption” were uncertain at the time. Although the calcium content of the meal appeared to be part of it, milk didn’t seem to help and even made things worse. What about calcium supplements? Some assert that calcium supplements may help in reducing lead absorption in children, but “recommendations…must be based on evidence rather than conviction.” What’s more, those assertions are based in part on studies on rodents, and differences in calcium absorption and balance between rats and humans make extrapolation tricky. What you have to do is put it to the test. Researchers found that even an extra whopping 1,800 mg of calcium per day had no effect on blood lead levels. Therefore, the evidence doesn’t support conclusions that calcium supplements help.

What about whole foods? Reviews of dietary strategies to treat lead toxicity say to eat lots of tomatoes, berries, onions, garlic, and grapes, as they are natural antagonists to lead toxicity and therefore should be consumed on a regular basis. Remember those phytochelatins? Perhaps eating plants might help detoxify the lead in our own bodies or the bodies of those we eat.

These natural phytochelatin compounds work so well that we can use them to clean up pollution. For example, the green algae chlorella can suck up lead and hold onto it, so what if we ate it? If it can clean up polluted bodies of water, might it clean up our own polluted bodies? We don’t know, because we only have studies on mice, not men and women.

So, when you hear how chlorella detoxifies, they’re talking about the detoxification of rat testicles. Yes, a little sprinkle of chlorella might help your pet rat, or perhaps you could give them some black cumin seeds or give them a sprig of cilantro, but when you hear how cilantro detoxifies against heavy metals, I presume you don’t expect the researchers to be talking about studies in rodents. If we’re interested in science protecting our children, not just their pets, we’re out of luck.

The same is true with moringa, tomatoes, flaxseed oil, and sesame seed oil, as well as black grapes, and black, white, green, and red tea. There are simply no human studies to guide us.

Dietary strategies for the treatment of lead toxicity are often based on rodent studies, but, for tofu, at least, there was a population study of people that showed lower lead levels in men and women who ate more tofu. The researchers controlled for a whole bunch of factors, so it’s not as if tofu lovers were protected just because they smoked less or ate less meat, but you can’t control for everything.

Ideally, we’d have a randomized, placebo-controlled study. Researchers would take a group of people exposed to lead, split them into two groups, with half given food and the other half given some kind of identical placebo food, and see what happens. It’s easy to do this with drugs because you just use look-alike sugar pills as placebos so people don’t know which group they’re in, but how do you make placebo food? One way to do disguised food interventions is to use foods that are so potent they can be stuffed into a pill—like garlic. There had been various studies measuring the effects of garlic in rats and looking at garlic as a potential antidote for lead intoxication distributed among different mouse organs, but who eats mouse organs? One animal study did have some direct human relevance, though, looking at the effect of garlic on lead content in chicken tissues. The purpose was to “explore the possible use of garlic to clean up lead contents in chickens which”—like all of us on planet Earth—“had been exposed to lead pollution and consequently help to minimize the hazard” of lead-polluted chicken meat.

And…it worked! As you can see at 1:59 in my video Best Food for Lead Poisoning: Garlic, feeding garlic to chickens reduced lead levels in the “edible mass of chicken” by up to 75 percent or more. Because we live in a polluted world, even if you don’t give the chickens lead and raise them on distilled water, they still end up with some lead in their meat and giblets. But, if you actively feed them lead for a week, the levels get really high. When you give them the same amount of lead with a little garlic added, however, much less lead accumulates in their bodies.

What’s even more astonishing is that when researchers gave them the same amount of lead—but this time waited a week before giving them the garlic—it worked even better. “The value of garlic in reducing lead concentrations…was more pronounced when garlic was given as a post-treatment following the cessation of lead administration”—that is, after the lead was stopped and had already built up in their tissues. We used to think that “the beneficial effect of garlic against lead toxicity was primarily due to a reaction between lead and sulfur compounds in garlic” that would glom on to lead in the intestinal tract and flush it out of the body. But, what the study showed is that garlic appears to contain compounds that can actually pull lead not only out of the intestinal contents, but also out of the tissues of the body. So, the “results indicate that garlic contain chelating compounds capable of enhancing elimination of lead,” and “garlic feeding can be exploited to safeguard human consumers by minimizing lead concentrations in meat….”

If garlic is so effective at pulling lead out of chickens’ bodies, why not more directly exploit “garlic feeding” by eating it ourselves? Well, there had never been a study on the ability of garlic to help lead-exposed humans until…2012? (Actually, I’m embarrassed to say I missed it when the study was first published. That was back when I was just getting NutritionFacts.org up and running. Now that we have staff and a whole research team, hopefully important studies like this won’t slip through the cracks in the future.)

The study was a head-to-head comparison of the therapeutic effects of garlic versus a chelation therapy drug called D-penicillamine. One hundred and seventeen workers exposed to lead in the car battery industry were randomly assigned into one of two groups and, three times a day for one month, either got the drug or an eighth of a teaspoon of garlic powder compressed into a tablet, which is about the equivalent of two cloves of fresh garlic a day. As expected, the chelation drug reduced blood lead levels by about 20 percent—but so did the garlic. The garlic worked just as well as the drug and, of course, had fewer side effects. “Thus, garlic seems safer clinically and as effective,” but saying something is as effective as chelation therapy isn’t saying much. Remember how chelation drugs can lower blood levels in chronic lead poisoning, but they don’t actually improve neurological function?

Well, after treatment with garlic, significant clinical improvements were seen, including less irritability, fewer headaches, and improvements in reflexes and blood pressure, but these improvements were not seen in the drug group. They weren’t seen after treatment with the chelation therapy drug. So, garlic was safer and more effective. “Therefore, garlic can be recommended for the treatment of mild-to-moderate lead poisoning.


 There are also some human studieson vitamin C. Check out Can Vitamin C Help with Lead Poisoning?.

For even more lead videos, see:

To learn more about chlorella, see:

In health,

Michael Greger, M.D.

PS: If you haven’t yet, you can subscribe to my free videos here and watch my live presentations:

Discuss

Michael Greger M.D., FACLM

Michael Greger, M.D. FACLM, is a physician, New York Times bestselling author, and internationally recognized professional speaker on a number of important public health issues. Dr. Greger has lectured at the Conference on World Affairs, the National Institutes of Health, and the International Bird Flu Summit, testified before Congress, appeared on The Dr. Oz Show and The Colbert Report, and was invited as an expert witness in defense of Oprah Winfrey at the infamous "meat defamation" trial.


19 responses to “Garlic Powder to Lower Lead Levels

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        1. I ended up re-writing the list in an order that made more sense to me and I saved the picture and list in Google Keep which I have on my phone.

          I was very happy that the list was saved in a text size that I can read.

          I have to mentally keep my mind thinking properly before grocery shopping.

          I am still craving Amy’s vegan pizza and that shows me that pizza is a food addiction food for me but it is fascinating because after I gave up cheese, I went out a few times and had restaurant pizza with real cheese and felt so sick and bound up that I don’t crave regular pizza. But tasting the vegan pizza triggered the brain to want it every night.

          I have that same thing with Reeses Peanut Butter cups which I haven’t eaten but I have had food cravings for it since the pot candy wrappers and it is such a pain-in-the-neck that now I have 2 food cravings.

          Mentally, this is my list pre-grocery shopping to undo it.

          Low DHA/EPA
          Elevated C-Reactive Protein
          Excess Cholesterol
          Excess Triglycerides
          Excess LDL
          Oxidized LDL
          Low HDL
          Excess Insulin
          High Glucose
          Low Nitric Oxide
          Low Vitamin D
          Low Vitamin K
          High Homocysteine (Low B12 and Folate)
          Excess Estrogen
          Low Free Testosterone
          Hypertension

        2. Looking over the blood test panels I think they missed an important one. Ferritin level should be done also as high iron levels are a known factor in heart disease.

  1. I paused at the sentence saying, “all higher plants” and I am not sure that I know what a higher plant is (versus a lower plant?)

    I also paused at the foods that are natural antagonists to lead toxicity: tomatoes, berries, onions, garlic, and grapes and wondered if the onion can be chopped ahead of time for that benefit or is it another case where the superpower only happens for a little while after chopping?

    Possibly tofu and green tea.

    And then, I paused at: “What’s even more astonishing is that when researchers gave them the same amount of lead—but this time waited a week before giving them the garlic—it worked even better.” and applauded. Works even better a week later is my kind of process.

    Now that I know that a lot of people are bringing lead into my proximity, I will be utilizing this information.

    1. Marguerite,

      In the blog above it said that one of the chelation drugs removed about 20%.

      It doesn’t say IV, so I am not sure about that.

      But garlic removed the exact same 20%.

      Modified Citrus Pectin has a study for removing lead (But with that, if Pectasol isn’t lying there are a lot of brands of Modified Citrus Pectin that are not small enough. There are a few brands that have been modified by enzymes to be small enough.)

      https://pubmed.ncbi.nlm.nih.gov/18616067/

  2. Slow cooked beans (like pinto beans)can lower lead levels. I had a client who’s baby had high lead levels and significantly reduced the levels (29 down to 9) by feeding her son slow cooked beans at least once daily.
    I will look for the science that backs this up.

  3. Hi Doc Greger,

    An error in your blog that says 45 mg. I believe you mean 45 mcg, for micrograms. I actually have a preference for the scientific literature way to specify micrograms, µg.

  4. Actually, I have a question on another food. I was wondering what your research has turned up about natto and/or vitamin K2. When I started eating natto every day, I felt like I had been awakened out of a zombie state. I used to take plant hormone replacement for my bones, but I have stopped, since I believe the K2 and vitamin D3 together are probably working better for my bones. I am anxious to hear what the research says.

  5. I diagnosed myself with lead poisoning 40 years ago when I was finishing up grad school. On the day I had an appointment to see a MD to confirm the diagnosis I tried crossing a 4 lane street, and had to rest on the island for 5 minutes because I was so tired from having crossed 2 lanes. The doc confirmed the diagnosis and said I had a month left to live, the lead poisoning was so bad. He gave me a dozen or so nutritional supplements to take, the only one that I remember being sodium alginate (dried seaweed). I took the first dose in his office and drove home which was an hour away. When I got there I went for my premorbid 7 mile run, doing 6:30 minute/miles. It was the MOST AMAZING recovery of my life. Screw big Pharma, the answer lies in nutrition.

  6. Glen,

    Good for you and glad to hear your still with us.

    You might consider a more aggressive approach for the residual lead, such as DMSA orally or perhaps even up the intensity via injectable EDTA ? Plenty of good data on these subjects and the safety is pretty well established, when used properly.

    Dr. Alan Kadish moderator for Dr. Greger http://www.Centerofhealth.com

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