IGF-1 as One-Stop Cancer Shop

IGF-1 as One-Stop Cancer Shop
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Insulin-like growth factor (IGF-1) is a natural human growth hormone instrumental in normal growth during childhood, but in adulthood can promote abnormal growth—the proliferation, spread (metastasis), and invasion of cancer.

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Why do centenarians escape cancer (people who live to be over 100 years old)?

As we get older, our risk of getting and dying from cancer grows year by year—but, once you hit about 85-90, your cancer risk starts to drop.

It kind of makes sense; I mean, if you didn’t get it by then, maybe you’re never going to get it. If you live that long, maybe it’s a sign that there’s something special about you. It seems that centenarians are endowed with a particular resistance to cancer. So, what’s their secret?

Well, every day, 50 billion of our cells die. And every day, 50 billion new ones are born. There’s a balance. Otherwise our body would atrophy, shrink, or get too big and crowded.

Now, sometimes we need to grow, like when we’re a baby, or that growth spurt around puberty. Our cells don’t get larger when we grow up; they get more numerous. A child’s hand may only be made up of about 50 billion cells, and may have to add a half trillion or so growing up.

Once we’ve already grown up, we don’t want a lot of extra cells hanging around. We still need our cells to grow and divide; out with the old, in with the new. We just don’t want to be making more cells than we’re putting out to pasture. When you’re a kid, extra growth can be good; when you’re an adult, extra growth can mean a tumor.

How do our cells know when to tip the balance in favor of more dividing and less dying, and when to come back into balance? A key signal is IGF-1, a growth hormone called insulin-like growth factor number 1. Levels goes up when you’re a kid, so you grow, and then come back down. Should your levels stay a bit too high as an adult, though, there’s this constant message to your cells grow, grow, grow; divide; don’t die; keep going; keep growing.

And so, not surprisingly, the more IGF-1 we have in your bloodstream, the higher our risk for cancer. More IGF-1, more prostate cancer; more IGF-1, more breast cancer.

Of course, it’s not the original tumor that tends to kill you; it’s the metastases. IGF-1 is a growth factor. It helps things grow, so it helps cancer cells break off from the main tumor, migrate into surrounding tissues, and invade the bloodstream.

What do you think helps breast cancer get into the bone? IGF-1. And the liver? IGF-1. Lung, brain, lymph nodes? IGF-1. It helps transform normal cells into cancer cells in the first place, then helps them survive, proliferate, self-renew, grow, migrate, invade, stabilize into new tumors, and even helps hook the blood supply up to the new tumor. IGF-1 is a growth hormone that makes things grow—that’s what it does. But too much growth, when we’re all grown up, can mean cancer.

Next, we’ll turn to how we can prevent all this.

To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video. This is just an approximation of the audio contributed by Kerry Skinner.

Please consider volunteering to help out on the site.

Images thanks to Danielle Keller via Wikimedia Commons and SanShoot via flickr.

Why do centenarians escape cancer (people who live to be over 100 years old)?

As we get older, our risk of getting and dying from cancer grows year by year—but, once you hit about 85-90, your cancer risk starts to drop.

It kind of makes sense; I mean, if you didn’t get it by then, maybe you’re never going to get it. If you live that long, maybe it’s a sign that there’s something special about you. It seems that centenarians are endowed with a particular resistance to cancer. So, what’s their secret?

Well, every day, 50 billion of our cells die. And every day, 50 billion new ones are born. There’s a balance. Otherwise our body would atrophy, shrink, or get too big and crowded.

Now, sometimes we need to grow, like when we’re a baby, or that growth spurt around puberty. Our cells don’t get larger when we grow up; they get more numerous. A child’s hand may only be made up of about 50 billion cells, and may have to add a half trillion or so growing up.

Once we’ve already grown up, we don’t want a lot of extra cells hanging around. We still need our cells to grow and divide; out with the old, in with the new. We just don’t want to be making more cells than we’re putting out to pasture. When you’re a kid, extra growth can be good; when you’re an adult, extra growth can mean a tumor.

How do our cells know when to tip the balance in favor of more dividing and less dying, and when to come back into balance? A key signal is IGF-1, a growth hormone called insulin-like growth factor number 1. Levels goes up when you’re a kid, so you grow, and then come back down. Should your levels stay a bit too high as an adult, though, there’s this constant message to your cells grow, grow, grow; divide; don’t die; keep going; keep growing.

And so, not surprisingly, the more IGF-1 we have in your bloodstream, the higher our risk for cancer. More IGF-1, more prostate cancer; more IGF-1, more breast cancer.

Of course, it’s not the original tumor that tends to kill you; it’s the metastases. IGF-1 is a growth factor. It helps things grow, so it helps cancer cells break off from the main tumor, migrate into surrounding tissues, and invade the bloodstream.

What do you think helps breast cancer get into the bone? IGF-1. And the liver? IGF-1. Lung, brain, lymph nodes? IGF-1. It helps transform normal cells into cancer cells in the first place, then helps them survive, proliferate, self-renew, grow, migrate, invade, stabilize into new tumors, and even helps hook the blood supply up to the new tumor. IGF-1 is a growth hormone that makes things grow—that’s what it does. But too much growth, when we’re all grown up, can mean cancer.

Next, we’ll turn to how we can prevent all this.

To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video. This is just an approximation of the audio contributed by Kerry Skinner.

Please consider volunteering to help out on the site.

Images thanks to Danielle Keller via Wikimedia Commons and SanShoot via flickr.

Doctor's Note

This video seems like a departure from the last five videos, which describe an Ex Vivo Cancer Proliferation Bioassay, but those who’ve seen my full-length presentation, Uprooting the Leading Causes of Death, know that this all circles around in the end. I’ve touched on IGF-1 before, in Daily Hormonal Interference and Meat Hormones & Female Infertility, but soon you’ll know everything you wanted to about it (but may have been afraid to ask!).

For more context, be sure to check out my associated blog posts: Eating To Extend Our LifespanStool Size and Breast Cancer RiskAnimal Protein and the Cancer Promoter IGF-1Estrogenic Chemicals in Meat; and How Do Plant-Based Diets Fight Cancer?

If you haven’t yet, you can subscribe to my videos for free by clicking here.

60 responses to “IGF-1 as One-Stop Cancer Shop

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  1. This video seems like a departure from the last 5 videos, which describes an Ex Vivo Cancer Proliferation Bioassay, but those who’ve seen my full-length presentation Uprooting the Leading Causes of Death know that this all circles around in the end. I’ve touched on IGF-1 before in Daily Hormonal Interference and Meat Hormones & Female Infertility, but soon you’ll know everything you wanted to about it (but may have been afraid to ask!).

    If you haven’t yet, you can subscribe to my videos for free by clicking here.




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    1. Its the same hormone actually. The supplement industry for bodybuilders has a very damaging impact on those consuming their products. Little do people know that most of the supplements they take is either useless or harmful.




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      1. Mucuna pruriens or velvet bean is known to promote HGH , what about that ? KaunchBeej powder is a very popular herb here in India.




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  2. I guess that in the next videos you are going to show that bovine IGF-1 is identical to human IGF-1, that it survives digestion, and eventually enters circulation to boost the endogenous levels of IGF-1. Which means, cow milk is the best way to promote cancer.




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    1.  I hope so. If not identical then similar enough that we cannot discount that cow milk hormone may affect us in similar way. I mean we ARE drinking a milk that is meant to make animals grow. We are animals. The only ones that drink milk into adulthood and the only ones that drink milk from another species, they say. I just can’t believe that if it were a good practice that nature would have just goofed and not made it a natural food for animals. We need to stop thinking we know so much more than what the natural world is screaming at us. I believe our bodies are BEGGING us to stop consuming dairy and the horrible end result of us ignoring them is disease. Animals aren’t as sick as we are in nature and surely much of that is the result of eating their perfect natural diet. We need to just eat our perfect natural diet. There is a bounty out there and dairy isn’t part of it.




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      1. Agree..

         Re.animals:  they are sick and die young ..because of the polluted environment man has created and because we keep moving their habitat. 




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      2. Flawed thinking. Milk is simply not available to adult animals. That is why they don’t drink it. Would it make any sense for adult animals to feed each other? No. They need to get energy from external sources.
        Humans started using diary as soon as they figured out how to get the milk. Sounds pretty natural now. Learning how to make fermented diary products promoted rapid adoption of dairy for even those who are lactose intolerant.
        Dairy demonization has no legs except in our current days of adding in hormones and antibiotics. Take that away and dairy is an excellent food source.




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        1. “Would it make any sense for adult animals to feed each other? No.” Well what do you call an adult bovine animal feeding an adult human animal? Makes no sense, Peakview.




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      3. YEAH! But “Milk Does the Body Good” or better put: “Milk provides huge profits (at our expense) for the Food Industry” WHO has a huge pull in the political circles- so the truth, along w/ all the pink ribbon/fund raising/Big Pharma/Monsanto, etc etc- Aren’t really interested in our well being as they are in their profits- ALL at our expense. Wake up people- eat the way nature intended. It’s all just common sense.




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    1. No, a high meat diet has the potential to put children at risk for early puberty, which puts them at risk for chronic illnesses later in life. Children have naturally elevated levels of IGF-1 in their body. Eating vegan does not hamper this level.




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    2. No, very few children have died due to vegan diets, and usually these are those where it’s been given to them too early on.




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    1. This truly is shocking! I couldn’t understand the article very well. Did they say whether the cancer promoted the levels, or were the levels already high from lifestyle or supplements? I know zinc increases igf-1, and some parents worry their kids need vitamins and minerals so they give them multi-supplements which have zinc in them.
      Also, a lot of older men take zinc supplements, ironically to help keep their prostate healthy. Its frustrating how something can be helping and harming at the same time.




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      1. So using hgh secretagogues (amino acids, etc.) at an older age would possibly + correlate with cancer incidence? Or is there a reduced correlation at older ages? At one time lef.org was selling an IGF-1 supplement….might still do so.




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      1. There’s a weak association with carbs in observational studies. For the most part IGF is how a surplus of complete protein is signalled.

        On cell membranes, there are insulin receptors, IGF receptors, and hybrids of the two, and they all effect similar downstream pathways. Oncologists use the abbreviation IIRF (insulin and insulin-like growth factor I receptor family), and some think excess insulin signalling through the IIRF links metabolic syndrome, obesity and cancer risk. Some bodybuilders take advantage of these hybridized pathways by injecting insulin to increase muscle growth.




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  3. I tried to post this on another topic but got it under the wrong caption
    to my question, so here goes. I am 67 year old make and was diagnosed
    with prostate cancer (Gleason=8) four years ago and immediately switched to a strict vegan nutritional base. I’ve been an avid fan of Nutrition Facts (post them on my Pinterest site daily). For the first time I had my IGF-1 level checked (my doctor didn’t have a clue as to why) after reading/hearing about the beneficial impact of a low IGF-1. Mine is now 105 (very low?) and my testosterone is over 800; just as the doctor’s video mentioned! But is it low enough to combat my prostate cancer (recent PSA=7 up from 5.8 4 months ago)). Most of my blood work is terrific (HDL=71 LDL-74, Triglycerides=38).

    It is really hard to develop targets for some of these tests and I
    want to better understand how I should proceed. Current literature is
    all over the place and none/few address prostate cancer and nutrition.

    Tell Dr. Greger thanks for his guidance.

    Skip Stein




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    1. My husband was diagnosed with prostate cancer and we actually ‘lowered’ his PSA by eliminating sugar from our diet. We observed a no white trash diet and his PSA went down almost 2 points. No flour, no sugar, no potatos, no fruit, no milk. It is rough for the first couple of weeks, but the cravings go away and the result was great. My naturalpath had at least 5 former prostate cancer patients who were ‘cured’ by diet alone. Food does make a difference.




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  4. Just watched a doco on BBC on this, apparently all you need to do to half your IGF levels, is have 2 days a week where you eat only 1 meal for that day.

    Some people even go as far as every second day.




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  5. mY 7 YEAR OLD SON HAS LOW IGF-1. WHAT DOES THIS MEAN? IT WORRIES ME? HES BEEN GOING TO AN ENDOCRINOLOGIST FOR HIM BEING SO UNDER WEIGHT AND THIN..




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  6. People – IGF-1 is also used for many other good things and growing is one of them. If you want to sit around on the couch and inject IGF-1 and think you’re going to grow then yes you’re probably going to grow a tumor. If you are working out and breaking your body down to build it up then IGF-1 becomes a way to recover and help with damaged areas. Also if you have a headache do you take an entire bottle of aspirin? Of course you don’t because you don’t want to die. The same should be said for anyone looking to take IGF-1. Like any drug prescribed from a doctor or supplement bought from a store research and education can help you safe guard yourself from ignorant mistakes. Again if you are breaking your body down seriously then IGF-1 helps in all sorts of great ways to shuttle nutrients to damaged areas. When it comes to cancer there are many variables but IGF-1 is obviously one link of a much larger chain and we shouldn’t demonize it just because one study shows it caused cancer. What about all the people smoking cigarettes or have extremely poor diets?




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  7. This is pure pseudo scientific alarmist.

    While drinking rBST milk can increase ORAL IGF-1 intake, it has been proven over and over again that this doesn’t increase SERUM BLOOD levels of IGF-1. IGF-1, as well as other proteins, amino acids and peptides, are rapidly denatured in the GI track. rBST milk does not raise SERUM BLOOD levels of IGF-1 because it never passes the gut. At any rate, binding proteins will inhibit unbound IGF-1 is under 20 minutes. Other BPs effectly “tie up” 99% of the body’s IGF-1 at a given time. Hormonal feed back loop much?




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  8. Do you think a change in diet can help someone with acromegaly? My boyfriend has tried but hasn’t been able to completely cut out dairy. He doesn’t eat meat or drink milk but still eats cheese and eggs. His heart doctor told him to add fish back into his diet recently. Any recommendations?




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    1. Hi Benni. I do not see much in the literature. Dr. Greger seems to only have one video that briefly mentions acromegaly. I think a healthful diet is important regardless of the condition at hand. I would listen to his doctor, but you may want to ask about plant-sources of omega 3’s, as they could be an alternative if he is trying to avoid fish.




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    2. Much of fish is now high in mercury. I would check out what fish is safe to eat.
      In my opinion, eggs are one of the healthiest foods you can eat as long as you have no problems with it. Preferably not from crowded, diseased chickens, either.




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  9. I’m a 27 year old male and I currently have testicular cancer but have not received treatment (chemo/radiation) for this. I typically eat a vegan diet, but here’s the tricky part. I also love to bodybuild; my supplements currently involve: creatine, glutamine, and a concentrated functional protein. The functional protein actually works as much as 25x the regular dose of whey protein, all in one scoop, which means the protein heavily increases the igf-1 within my body; Should I be avoiding these supplements completely? I would highly appreciate any feedback and info on combatting this cancer with proper nutrition.




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  10. I was reading one of those informercials that sound like nutritional advice until you get to the end when they offer a guide to lose weight, freshen breath. make you pretty and whiten your teeth valued at gazillion dollars all for the ridiculous (their word) amount of $19.95. This one, which I copied and pasted :
    THE METABOLIC FACTOR™
    The World’s First All-Natural IGF-1 Boosting
    Weight Loss And Body Rejuvenation System
    Designed To Give You Sustainable, Enjoyable And
    Lifestyle-Friendly Fat-Burning In Just 22 Days!
    I decided to research IGF-1 and found this website that warns about the very same thing Dr. Jonny Bowden is touting! He even answered a question about taking supplements by saying that he’ll talk about it once you purchased his program. Now he does offer a 60 day money back guarantee so he must believe in what he’s selling, right? Any feedback is appreciated. Thanks.




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      1. I found this site because I wanted more information on IGF-1 and the metabolic factor advertised by Jonny Bowden too. Now I’m more confused and cautious as it can cause cancer to grow. How could he not know this? My husband and I could use some help but it sounds like at 71 and 72 we should stay away from any IGF-1 boosting system including dietary.




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        1. helen: There is definitely a lot of conflicting information out there. Also, it is easier to prevent a problems than to reverse them. There are no guarantees. Having said that, people have reported remarkable recoveries after switching to healthy diets even when done late in life. Here is a video with evidence about it never being too late to start eating healthy: http://nutritionfacts.org/video/never-too-late-to-start-eating-healthier/
          .
          Are you concerned about a particular problem, such as diabetes? Or would you like tips on what a healthy diet looks like based on what the body of scientific evidence says?
          .
          Here is a great starting video if you just want some general information about the body of evidence. I highly recommend it. http://nutritionfacts.org/video/uprooting-the-leading-causes-of-death/
          .
          If you just want more information about IGF-1, this video on the page you commented on is just one video in a series on the topic. You might want to watch the whole series.
          .
          Good luck.




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  11. As a vegan people ask me, “But where do you get your protein”. Then they brag about having a big juicy steak at a BBQ. Okay!




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      1. As a meat eater, I answer: From grains and veggies of course! It’s not like meat eaters only eat meat 24/7 -_-




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        1. Marko Amore Peratalo: That sure sounds logical. However, did you know that most meat eaters (more than 97%) are fiber deficient? At least in America: http://nutritionfacts.org/2015/09/29/where-do-you-get-your-fiber/ = Hence the need to worry about fiber for meat eaters, but no worries about protein for whole plant food eaters.
          .
          I hope you are one of the exceptions and you get enough fiber. With such very low daily recommendations for fiber, it is certainly possible for a meat eater to get enough fiber. So, I would have no problem believing you are one of the lucky ones.




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          1. I did not know that. Sounds like a crazy high number! Then again most people do everything wrong and have no clue about nutrition… Lack of fiber on general folk is probaly explained by most people only having minimal amount of veggies on 1, or max 2, meals a day with a possible 1 fruit per day… This is also how I used to eat as a kid. But thanx to mom for switching to whole grain rice/pasta at some point in our lives, thus I also have been eating exclusively whole grains for over 10 years. And since becoming a recreational bodybuilder 9 years ago, I completely overhauled my eating habits and they are as healthy and as balanced as possible. Though I have actually never counted my fiber intake and my diet changes drastically depending on what phase I’m on my training. But I believe having greens at about every meal and preferring whole grains cover the essentials.

            I don’t think most vegans come even close to meeting the _actual_ recommended protein intake. The average intake mentioned in ur link (42 grams per day) is laughable! :D That’s like for a 7 year old kid maybe! Besides, meeting the MINIMUM intake is nothing to rave about. A better approach is to meet the OPTIMAL intake for best body composition. The very minimum protein intake is 1g/kg, but it’s better to eat in the 1,5-2g/kg range if ur exercise (as everyone should!) or if u wanna lose fat/gain muscle. Most vegans I know are very skinny and it’s no surprise if they think something like ~42g of protein is enough… And 80% of the vegans I know are women, and as most women I know (including normal eaters): they eat way too little calories, so that’s another reason why half of them are skinny, but half are stuck on being fat because they have driven their body into starvation mode…




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            1. Marco Amore Peratalo: re: “…I have actually never counted my fiber intake…” If you want to count fiber and a bazillion other nutrients, many people enjoy using cronometer.com

              re: Protein. I agree that we should work towards optimal protein intakes, not minimal to get us by. The question is, what is optimal? Did you know that they figured out minimum protein needs and then doubled them. And them doubled them again. And *those* numbers (4 times the minimum) are the current recommended protein amounts? For a wonderful protein 101 article, and a great myth buster check out: http://michaelbluejay.com/veg/protein.html

              You might also appreciate the history behind protein recommendations. The article from Dr. McDougall’s newsletter from December 2003 is simply fascinating.
              http://www.drmcdougall.com/health/education/newsletter/archives/
              You might also check out the January 2004 newsletter article, Protein Overload.

              Finally, it’s great to hear that you are into body building. Did you know that vegans are winning metals and making world records right and left? I’ll include some information about vegan body builders and athletes in a follow up post so that this post does not get too long. The bottom line is that eating any significant amounts of animal protein is shooting yourself in the foot if you want to excel at bodybuilding. Good luck!




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            2. Marco: As promised, here are some sample stories of body builders and athletes who make great gains after they start to eat a healthy diet, free of meat, dairy and eggs.

              **************************
              (article from meatout mondays)
              Vegan Bodybuilders Dominate Texas Competition

              The Plant Built (PlantBuilt.com) team rolled into this year’s drug-free, steroid-free Naturally Fit Super Show competition in Austin, TX, and walked away with more trophies than even they could carry.

              The Plant Built team of 15 vegan bodybuilders competed in seven divisions, taking first place in all but two. They also took several 2nd and 3rd place wins.

              For More Info: http://www.plantbuilt.com/

              ———————
              When Robert Cheeke started VeganBodybuilding.com in 2002, being the only vegan athlete he knew of, he may not have imagined that the website would quickly grow to have thousands of members. Robert says, “We’re discovering new vegan athletes all the time, from professional and elite levels… to weekend warriors and everyone in between.”

              For More Info: http://www.veganbodybuilding.com/
              —————–
              There was that other guy who just did a world record in weight lifting. “Congratulations to Strongman Patrik Baboumian who yesterday took a ten metre walk carrying more than half a tonne on his shoulders, more than anyone has ever done before. After smashing the world record the Strongman let out a roar of ‘Vegan Power’…” For more info:
              http://www.onegreenplanet.org/news/vegan-strongman-patrik-babaoumain-breaks-world-record/
              another article on the same guy: http://www.thestar.com/news/gta/2013/09/08/vegan_strongman_shoulders_550_kg_a_record_perhaps_at_vegetarian_food_fest.html
              And another article: “I got heavier, I got stronger, I won the European championship title in powerlifting, I broke three world records so everything was going perfect … my blood pressure went down, and my recovery time was so much faster so I could train more.” http://edition.cnn.com/2016/07/06/health/vegan-strongman-patrik-baboumian-germany-diet/
              —————–
              Here’s a story about a bodybuilder who doesn’t use any supplements. Just eats whole plant foods:
              http://www.forksoverknives.com/vegan-bodybuilder-plant-based-diet/?mc_cid=b8b1865825&mc_eid=09aaf03269
              —————–
              Mr Universe – “Since going vegan, he has actually gained even more mass, now at 107 Kilos…”
              http://www.thediscerningbrute.com/2015/07/14/mr-universe-goes-vegan/
              —————–
              Bite Size Vegan has a youtube channel
              “In this video series, you’ll hear from various vegan athletes from all walks of life and athletic abilities speaking to such topics as vegan athletic performance, building muscle on a vegan diet, vegan endurance running, bodybuilding, body image, and more!”
              https://www.youtube.com/playlist?list=PLmIqdlomtuSv9FQJgdj3Bwg9Nh9MNjKg4
              —————–
              Here’s another site that I like:
              http://www.greatveganathletes.com/

              I found this story on the above site: “Pat Reeves has set a new world powerlifting record at the WDFPA World Single Lift Championships. The 66 year old lifter, who has been vegan for 46 years, lifted 94 kg to set a record for the under 50.5kg weight class while competing in France in June 2012. The lift was more than 1.85 times her bodyweight, which is exceptional for her division. Pat is now officially the oldest competing weightlifter in Europe.”

              ————————-
              Story of Mac Denzig, winner of season six of The Ultimate Fighter
              http://www.ufc.com/news/Mac-Danzig-Diet-The-Truth-About-Vegan
              http://www.sherdog.com/fighter/Mac-Danzig-3396
              http://www.mikemahler.com/online-library/articles/mma-training/ufc-fighter-mac-danzig-vegan-diet.html
              ————————–
              Book: Vegan Bodybuilding And Fitness by Robert Cheeke
              http://www.amazon.com/Vegan-Bodybuilding-Fitness-Robert-Cheeke/dp/0984391606/ref=sr_1_1_title_0_main?s=books&ie=UTF8&qid=1396982744&sr=1-1&keywords=vegan+bodybuilding

              ————————–
              And another article from Meetout Mondays:

              Vegan Figure Skater Takes Silver
              Canadian Olympian Meagan Duhamel and her partner Eric Radford won a silver medal in pairs figure skating at this year’s Olympic games in Sochi, Russia.

              Duhamel proudly took to Twitter announcing that she is an “Olympian, vegan, yogi and nutritionist.” Wonderful! Congratulations to Meagan for being an outspoken and shining example of what healthy vegan eating looks like. …

              —————–
              (from Meetout Mondays)
              Plant-Powered Athlete: Griff Whalen [NFL Player]
              His teammates say he has the most enviable body on the team. They say he consumes an average of 6,000 calories and 200 grams of protein a day. They also say, he does it all by eating plants!

              In a recent interview on IndyStar.com, Indianapolis Colts’ wide receiver Griff Whalen, talks about his vegan ways.

              “I feel a lot lighter, faster, quicker on the field. There isn’t that heavy feeling, that groggy feeling after I eat,” says Whalen.

              Hooray for another plant-powered athlete for us to cheer on. w00t! w00t!

              Read the full article on : org2.salsalabs.com/dia/track.jsp?v=2&c=X9u7eAG%2FDmVet3kwZgrmHD5TipkEhWa4
              ****************
              (from Meetout Mondays)
              NFL’s David Carter on Living Vegan: In an interview last month on Rich Roll’s podcast, 27 year old Chicago Bears’ defensive lineman, David Carter spoke of a day in the life of the NFL, what he eats daily, his vegan journey, and his commitment to animal advocacy.

              “I can honestly say that being vegan is not only the most efficient way to be full-body strong, it’s also the most humane; everyone wins,” Carter said on the podcast.

              Carter is also the founder of The 300 Pound Vegan, a lifestyle blog where the NFL player writes about his journey through veganism and shares plant-based recipes. If nothing else, Carter shows us that living on plants is not just for endurance athletes or yogis but can positively impact heavy hitters in terms of their size, speed, agility, power, and quickness. Aww, yeah! Thanks for being so rad, David. We love it!

              Listen to the full interview on Rich Roll: http://www.richroll.com/podcast/david-carter-300-pound-vegan/
              Or for a written story with sample menu plan: http://www.gq.com/story/vegan-diet-of-nfl-player-david-carter

              ——————————
              And another article from Meetout Mondays:

              Record Setting, 92 Yr Old Vegan Runner

              Mike Fremont has been vegan for over 20 years, and has been setting single age marathon running records just as long.

              “At age 88 [Mike] ran a 6H5M53S marathon in Cincinnati Ohio and at age 90 ran a 6H35M47S marathon in Huntington West Virginia. [He] also set a single age world record for 90 years old in the half marathon in Morrow Ohio in August 2012,” said Veg World Magazine.

              According to an interview with Veg World Magazine, Fremont credits his vegan lifestyle for his continued record setting runs, at his age.

              We love seeing vegans making positive media waves, and what better way to showcase the health benefits of plant-powered living than Mike’s awesome running career. Here’s to you Mike, and vegan athletes of all ages!

              Learn more about Mike Fremont a VegWorldMag.com.
              http://www.vegworldmag.com/amazing-92-year-old-vegan-runs-another-half-marathon/

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              from Meatout Mondays:

              World’s First Vegan Pro Soccer Team

              The Internet went wild last week as the news that English soccer (A.K.A football) team, the Forest Green Rovers, announced that the entire team and club is going completely vegan.

              “We stopped serving meat to our players, fans and staff about four seasons ago,” said club owner Dale Vince (via a recent article on Edition.CNN.com). He continued, “We’ve been on a mission since then to introduce our fans to this new world.” The article explains that while the club has been vegetarian for the past few years, they’ve decided to take the next step in going fully vegan (including their beer and cider options). Also cool to know: the club’s field is organic and they collect rainwater to use for irrigation. This is seriously super cool, you guys. Keep it up!

              Read the source article on: http://edition.cnn.com/2015/10/30/football/world-health-organization-meat-vegan-football/

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              from Meatout Mondays:
              Vegan Arm Wrestler: Rob Bigwood

              “Some of his opponents say that since going vegan Rob is stronger, his stamina grew, and he became more difficult to pin,” notes an interview-style Facebook post by ‘Starry N Ight.’

              A competitive arm wrestler since 2000, Rob Bigwood has been making a name for himself in the arm wrestling community—not only as the one to beat but also as the guy who eats plants. Rob has said, “I was concerned at first [about not eating meat for strength] but didn’t care. I made a conscious and ethical decision to give up meat…It is more important to practice what I believe in than to worry about being a strength athlete. I have never felt better in my entire life and it was one of the smartest decisions I ever made.”

              Check out one of Rob’s interviews on http://www.scribd.com/doc/39221267/Interview-with-a-Vegan-Arm-Wrestler

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              from Meatout Mondays:
              Vegan Bodybuilder Bucks Stereotypes

              Vegan bodybuilder Joshua Knox shares his game changing and inspiring vegan story during a TEDxFremont, California presentation.

              In this five-minute long video, shared by Mercy for Animals, Knox talks of his ‘meat and potatoes’ upbringing and what led him to give veganism a try. The results were nothing short of wonderful.

              “Not only was I able to continue increasing my strength and performance but also saw massive gains in endurance as well… [and] rather than feeling like I was missing out on foods I really felt that I was opening my mind to so many things I would have never put on my plate…” Knox said during his presentation. Joshua also noted a drop in his cholesterol, while experiencing mental and emotional health improvements as well. Rock on, Josh! Thank you for sharing your story

              Watch the short video on Mercy for Animals’ youtube channel: https://www.youtube.com/watch?v=43f2qWARXnA

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              from Meatout Mondays:
              Vegan Breaks World Record in Push-Ups

              A vegan from Kerala (a South Indian state) has just broken the Guinness World Record for knuckle push-ups (press ups). K.J. Joseph—a manager of an ayurveda centre in Munnar—completed 82 push-ups in 60 seconds, beating out Ron Cooper from the US who held the record at 79 push-ups in 2015. “Joseph has already entered the Universal Record Forum by doing 2092 push-ups in an hour. He is currently the record holder in the India Book of Records,” notes OnManorama.com. Thanks for making us vegans look good, Joseph. And congrats on your win!

              Check out the original story: http://english.manoramaonline.com/lifestyle/society/vegan-most-knuckle-push-up-guinness-world-record-joseph.html

              ———————————
              from Meatout Mondays:

              Professional Bodybuilding Couple Celebrate Veganism
              Named 2014 Mr Universe, Barny Du Plessis and his fiance, named UK’s strongest woman, Josie Keck are excited to share and to celebrate their one year vegan anniversary this month. In a comprehensive interview by British publication, Daily Mail, the vegan (literal) power couple are “…serious about [their] crusade to save the Earth, the animals, [themselves], and our dignity as a species,” said Barny. The articles noted that, “Barny is on a mission to destroy the idea that eating meat is associated with manliness.” He said, “I’m living proof that you simply don’t need to eat meat or animal products to make great gains, be strong, healthy, fit, and feeling mighty.” We couldn’t agree more, Barny. Congratulations to you both on your anniversary! We’re so jazzed you’re passionate about veganism.

              “When training for competitions Barny eats up to 4,500 calories a day, while Josie consumes 2,200 of vegan food. While preparing for a competition their typical diet consists of a wide variety of vegetables; fruit such as apples, bananas, dates and berries; grains such as basmati rice, quinoa and tapioca, pulses like chickpeas and brown and red lentils; as well as powders such as rice protein, hemp protein and vegan protein blend.” And the article includes a sample daily menu for each of them. http://www.dailymail.co.uk/femail/article-3495676/Obese-woman-met-fiance-gym-vegan-bodybuilders.html

              ——————-
              From PCRM Weekly News Update:
              What do the world’s top male and female tennis players have in common? They love vegan food! In a new Huffington Post piece, Dr. Barnard talks about plant-powered Novak Djokovic’s recent win at the French Open. http://new.www.huffingtonpost.com/neal-barnard-md/plantpowered-novak-djokov_b_10282348.html




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  12. I understand IGF-1assay ranges vary. Post breast cancer treatment (neo adjuvant chemo, bilateral, and full axial removal) was recently tested at 208 when normal range is 40 to 170. I have been vegan since April 2016, flex in vegetarian prior. I have no pre diagnosis data. Is there anormal range for post treatment cases? Can a specified range be used as marker of metastasis? Is there advise for reducing IGF-1 beyond vegan diet, such as ketogenic diet.




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    1. Hi Kathy, this is an area where a lot a research is being done so there are not very many conclusions as yet. We know that diet and weight affects the levels of IGF but how that affects tumors that are stimulated my IGF is less well known. Here are a couple of journal articles that were referenced by the professor teaching the integrative oncology course I am currently taking. https://www.ncbi.nlm.nih.gov/pubmed/24755714 This article talks about the association between cancer and elevated IGF levels. https://www.ncbi.nlm.nih.gov/pubmed/25837220 This article talks about how cancer decreased in those with greatly decreased carbohydrate ingestion, however the improvement was only seen in those that were obese at the time. Hopefully there is some information in one of these articles that may be of help to you.




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  13. If IGF-1 level is really the major risk factor,
    Then why most cancer cases appear later in life, rather than childhood and during early adulthood instead.
    After all, childhood and early adulthood, are the two period in life, in which there is a peak in the number of cells replication\division.




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  14. Also, if exercise induce neurogenesis.
    Doesn’t it mean that exercises may also contribute to the risk of developing brain tumors\ brain cancer?
    If IGF1 has the potential to trigger cancer growth and migration, i assume the same rule should be apply to the brain.




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  15. My dad has been taking Thrive hgh natural supplement for the past 18months. Last week he was diagnosed with a small cell very aggressive prostate carcinoma that has metastasized. He has no genetic history of cancer and is one of the healthiest people I know. His mom is 93 and in supreme health and grandpa died at 86 from dementia. I strongly believe that his cancer is from these high levels of HGH that have produced IGF-1. Anyone experience anything similar? Why do we not hear more stories like this? So far all I’ve read is that natural supplements are incapable of producing these levels sufficient enough to do any harm.
    This report has been very helpful. I’d like to research more.




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