Pomegranates are put to the test for weight loss, diabetes, COPD, prostate cancer, osteoarthritis, and rheumatoid arthritis.
Pomegranate: A Natural Treatment for Rheumatoid Arthritis
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Below is an approximation of this video’s audio content. To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video.
In a landmark case that made it all the way up to the U.S. Court of Appeals before being denied review by the Supreme Court, POM Wonderful (the pomegranate juice company) vs. Federal Trade Commission, a panel of judges concluded that many of POM’s ads made misleading or false claims touting medical studies ostensibly showing that pomegranate products could help treat various ailments, including heart disease, prostate cancer, and erectile dysfunction, and the First Amendment does not protect deceptive and misleading advertisements. Striking a blow to its billionaire owners, the Court ruled that at least one randomized clinical trial could be required to substantiate any claims of treating or preventing disease.
If you look at the medical literature on the benefits of pomegranates in general, you’ll see reviews like this, with diagrams like this on the “medicinal effects of pomegranate.” But if you dig a little deeper, you see this is based on studies like this: “antiobesity effects of pomegranate leaf extract in a mouse model.” First of all, who eats pomegranate leaves? And second of all, who’s a mouse? And if you do have a fat pet mouse, maybe just feed them less lard.
Does pomegranate consumption affect weight in humans? If you look at all the randomized controlled clinical trials (meaning human trials), pomegranates have no significant effect on body weight, BMI, belly fat, or even body fat percentage in those randomized to pomegranate product consumption. What about for the prevention and treatment of cardiovascular diseases? Researchers reviewed 25 clinical trials, looking at cholesterol, blood pressure, artery function, atherosclerotic plaque formation, and platelet function, and…even in the best studies, they did not find significant indications of benefit.
Here’s a study on pomegranate juice and erectile dysfunction. It was funded by the POM company, and yet it failed as well. No benefit for diabetes markers, and no benefit for chronic obstructive pulmonary diseases, like emphysema. They were banking on the antioxidant activity of pomegranate juice to help, but that’s antioxidant activity in vitro (meaning in a test tube or petri dish).
To my surprise, a meta-analysis of data from 11 randomized controlled trials did not support convincing evidence of pomegranate intake having a significant increasing effect on total antioxidant capacity of your bloodstream, because some of the most potent antioxidants don’t even seem to be absorbed into the human body. No wonder pomegranate supplementation didn’t seem to affect oxidative stress in tissue samples taken from prostate cancer patients. But, of course, what we care about is whether it affects the cancer Itself.
The strongest evidence for the anticancer activity of pomegranates is said to come from studies on prostate cancer. Unfortunately, early promising results were not confirmed when they were actually put to the test. For example, daily pomegranate Intake was found in a randomized controlled trial to have no impact on PSA levels, a marker of tumor progression. And, indeed, a randomized, double-blind, placebo-controlled trial found essentially no difference when it came to prostate cancer disease progression.
They were banking on the anti-inflammatory activity of pomegranate juice to help, but again, that had been demonstrated in vitro. In people, a meta-analysis based on five randomized controlled trials published in 2016 concluded that pomegranate juice did not have a significant effect on C-reactive protein levels, a key marker of inflammation. If you look at the forest plot, though, you’ll see all five trials tended towards lower C-reactive protein levels such that the data combined almost reached statistical significance. And indeed, an updated meta-analysis published in 2020 based on seven studies did indeed get tipped over into significance, and found a significant drop in two other inflammatory markers as well.
Huh, okay. Well, maybe pomegranate juice could help in the control of inflammatory diseases after all. But you don’t know, until you put it to the test.
Osteoarthritis involves the degeneration of the cushioning cartilage within joints, particularly the knees. If you take some human osteoarthritic cartilage samples and drip on a pomegranate extract, you can show cartilage-protective effects. Here’s how much cartilage disintegration was happening at baseline. Add some inflammation, and cartilage breakdown triples, but then add more and more of this pomegranate extract, and you can calm things down. But again, that’s in a petri dish. How do we know that when we eat pomegranates, the active components actually get into our bloodstream so they can find their way into our joints? Cartilage-protecting components were found to be bioavailable (at least in rabbits), raising the possibility that pomegranates could be a safe and nontoxic treatment with no side effects––as opposed to the drugs currently in use. But is it effective?
Clinical trials are in progress, and so many questions will be answered…right now! The first and only clinical trial to date on pomegranate juice and osteoarthritis. It’s not a placebo-controlled trial, but instead randomized people to pomegranate juice or nothing at all. Those drinking the juice did report less stiffness and impairment of physical function, but not significantly better than just doing nothing. Shoot.
But just as I was about to give up on pomegranates, I saw this study: Consumption of a pomegranate extract suppresses joint damage in rheumatoid arthritis. But no, it was just the POM ‘Not-So-Wonderful’ company inducing joint damage in a mouse as a model of rheumatoid arthritis. Come on!
What about this open-labeled study, where the patients knew what they were getting? Eight people with active rheumatoid arthritis took some pomegranate extract every day, and the six who stuck with it reported fewer tender joints. But as we learned from the osteoarthritis study, if you don’t have a control group you have no sense of what role, if any, the treatment actually plays.
And so finally, we come to this: a randomized, double-blind, placebo-controlled trial. It’s about time! Half of the subjects unknowingly got some pomegranate extracts; the other half unknowingly got the equivalent of a sugar pill and…significant improvement in the number of swollen joints, tender joints, pain intensity, a disease activity score, a health assessment questionnaire, and morning stiffness, compared to placebo. So, if you have rheumatoid arthritis, I would indeed recommend you start eating pomegranates. Why not just pop pomegranate pills? After all, it was a pomegranate extract that alleviated disease activity. One good reason to stick to the fruit is that when 19 pomegranate supplements were actually tested in a laboratory, most didn’t actually appear to have any pomegranate in them at all! Only 6 out of 19 appeared to be authentic.
Please consider volunteering to help out on the site.
- POM Wonderful, LLC v. Federal Trade Commission, 777 F.3d 478 (D.C. Cir. 2015)
- Sorvino C. The Verdict: POM Wonderful Misled Its Customers, A Blow To Its Billionaire Owners. Forbes. May 2, 2016.
- Court Mostly Backs FTC vs. Pomegranate Claims. Tufts Health & Nutrition Letter. March 11, 2015.
- Viuda-Martos M, Fernández-López J, Pérez-Álvarez JA. Pomegranate and its many functional components as related to human health: a review. Compr Rev Food Sci Food Saf. 2010;9(6):635-54.
- Gheflati A, Mohammadi M, Ramezani-Jolfaie N, Heidari Z, Salehi-Abargouei A, Nadjarzadeh A. Does pomegranate consumption affect weight and body composition? A systematic review and meta-analysis of randomized controlled clinical trials. Phytother Res. 2019;33(5):1277-88.
- Vlachojannis C, Erne P, Schoenenberger AW, Chrubasik-Hausmann S. A critical evaluation of the clinical evidence for pomegranate preparations in the prevention and treatment of cardiovascular diseases. Phytother Res. 2015;29(4):501-8.
- Forest CP, Padma-Nathan H, Liker HR. Efficacy and safety of pomegranate juice on improvement of erectile dysfunction in male patients with mild to moderate erectile dysfunction: a randomized, placebo-controlled, double-blind, crossover study. Int J Impot Res. 2007;19(6):564-7.
- Huang H, Liao D, Chen G, Chen H, Zhu Y. Lack of efficacy of pomegranate supplementation for glucose management, insulin levels and sensitivity: evidence from a systematic review and meta-analysis. Nutr J. 2017;16(1):67.
- Cerdá B, Soto C, Albaladejo MD, et al. Pomegranate juice supplementation in chronic obstructive pulmonary disease: a 5-week randomized, double-blind, placebo-controlled trial. Eur J Clin Nutr. 2006;60(2):245-53.
- Morvaridzadeh M, Sepidarkish M, Daneshzad E, Akbari A, Mobini GR, Heshmati J. The effect of pomegranate on oxidative stress parameters: A systematic review and meta-analysis. Complement Ther Med. 2020;48:102252.
- Cerdá B, Espín JC, Parra S, Martínez P, Tomás-Barberán FA. The potent in vitro antioxidant ellagitannins from pomegranate juice are metabolised into bioavailable but poor antioxidant hydroxy-6H-dibenzopyran-6-one derivatives by the colonic microflora of healthy humans. Eur J Nutr. 2004;43(4):205-20.
- Freedland SJ, Carducci M, Kroeger N, et al. A double-blind, randomized, neoadjuvant study of the tissue effects of POMx pills in men with prostate cancer before radical prostatectomy. Cancer Prev Res (Phila). 2013;6(10):1120-7.
- Turrini E, Ferruzzi L, Fimognari C. Potential effects of pomegranate polyphenols in cancer prevention and therapy. Oxid Med Cell Longev. 2015;2015:938475.
- Paller CJ, Pantuck A, Carducci MA. A review of pomegranate in prostate cancer. Prostate Cancer Prostatic Dis. 2017;20(3):265-70.
- Stenner-Liewen F, Liewen H, Cathomas R, et al. Daily pomegranate intake has no impact on psa levels in patients with advanced prostate cancer - results of a phase iib randomized controlled trial. J Cancer. 2013;4(7):597-605.
- Pantuck AJ, Pettaway CA, Dreicer R, et al. A randomized, double-blind, placebo-controlled study of the effects of pomegranate extract on rising PSA levels in men following primary therapy for prostate cancer. Prostate Cancer Prostatic Dis. 2015;18(3):242-8.
- Sahebkar A, Gurban C, Serban A, Andrica F, Serban M-C. Effects of supplementation with pomegranate juice on plasma C-reactive protein concentrations: A systematic review and meta-analysis of randomized controlled trials. Phytomedicine. 2016;23(11):1095-102.
- Wang P, Zhang Q, Hou H, et al. The effects of pomegranate supplementation on biomarkers of inflammation and endothelial dysfunction: A meta-analysis and systematic review. Complement Ther Med. 2020;49:102358.
- Danesi F, Ferguson LR. Could pomegranate juice help in the control of inflammatory diseases? Nutrients. 2017;9(9):E958.
- Ghoochani N, Karandish M, Mowla K, Haghighizadeh MH, Jalali MT. The effect of pomegranate juice on clinical signs, matrix metalloproteinases and antioxidant status in patients with knee osteoarthritis. J Sci Food Agric. 2016;96(13):4377-81.
- Ahmed S, Wang N, Hafeez BB, Cheruvu VK, Haqqi TM. Punica granatum L. extract inhibits IL-1beta-induced expression of matrix metalloproteinases by inhibiting the activation of MAP kinases and NF-kappaB in human chondrocytes in vitro. J Nutr. 2005;135(9):2096-102.
- Shukla M, Gupta K, Rasheed Z, Khan KA, Haqqi TM. Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1beta-induced PGE2 production in human chondrocytes in vitro. J Inflamm (Lond). 2008;5:9.
- Rasheed Z. Intake of pomegranate prevents the onset of osteoarthritis: molecular evidences. Int J Health Sci (Qassim). 2016;10(2):V-VIII.
- Shukla M, Gupta K, Rasheed Z, Khan KA, Haqqi TM. Consumption of hydrolyzable tannins-rich pomegranate extract suppresses inflammation and joint damage in rheumatoid arthritis. Nutrition. 2008;24(7-8):733-43.
- Balbir-Gurman A, Fuhrman B, Braun-Moscovici Y, Markovits D, Aviram M. Consumption of pomegranate decreases serum oxidative stress and reduces disease activity in patients with active rheumatoid arthritis: a pilot study. Isr Med Assoc J. 2011;13(8):474-9.
- Ghavipour M, Sotoudeh G, Tavakoli E, Mowla K, Hasanzadeh J, Mazloom Z. Pomegranate extract alleviates disease activity and some blood biomarkers of inflammation and oxidative stress in Rheumatoid Arthritis patients. Eur J Clin Nutr. 2017;71(1):92-6.
- Vlachojannis C, Zimmermann BF, Chrubasik-Hausmann S. Efficacy and safety of pomegranate medicinal products for cancer. Evid Based Complement Alternat Med. 2015;2015:258598.
- Madrigal-Carballo S, Rodriguez G, Krueger CG, Dreher M, Reed JD. Pomegranate (Punica granatum) supplements: Authenticity, antioxidant and polyphenol composition. J Funct Foods. 2009;1(3):324-9.
Motion graphics by Avo Media
Below is an approximation of this video’s audio content. To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video.
In a landmark case that made it all the way up to the U.S. Court of Appeals before being denied review by the Supreme Court, POM Wonderful (the pomegranate juice company) vs. Federal Trade Commission, a panel of judges concluded that many of POM’s ads made misleading or false claims touting medical studies ostensibly showing that pomegranate products could help treat various ailments, including heart disease, prostate cancer, and erectile dysfunction, and the First Amendment does not protect deceptive and misleading advertisements. Striking a blow to its billionaire owners, the Court ruled that at least one randomized clinical trial could be required to substantiate any claims of treating or preventing disease.
If you look at the medical literature on the benefits of pomegranates in general, you’ll see reviews like this, with diagrams like this on the “medicinal effects of pomegranate.” But if you dig a little deeper, you see this is based on studies like this: “antiobesity effects of pomegranate leaf extract in a mouse model.” First of all, who eats pomegranate leaves? And second of all, who’s a mouse? And if you do have a fat pet mouse, maybe just feed them less lard.
Does pomegranate consumption affect weight in humans? If you look at all the randomized controlled clinical trials (meaning human trials), pomegranates have no significant effect on body weight, BMI, belly fat, or even body fat percentage in those randomized to pomegranate product consumption. What about for the prevention and treatment of cardiovascular diseases? Researchers reviewed 25 clinical trials, looking at cholesterol, blood pressure, artery function, atherosclerotic plaque formation, and platelet function, and…even in the best studies, they did not find significant indications of benefit.
Here’s a study on pomegranate juice and erectile dysfunction. It was funded by the POM company, and yet it failed as well. No benefit for diabetes markers, and no benefit for chronic obstructive pulmonary diseases, like emphysema. They were banking on the antioxidant activity of pomegranate juice to help, but that’s antioxidant activity in vitro (meaning in a test tube or petri dish).
To my surprise, a meta-analysis of data from 11 randomized controlled trials did not support convincing evidence of pomegranate intake having a significant increasing effect on total antioxidant capacity of your bloodstream, because some of the most potent antioxidants don’t even seem to be absorbed into the human body. No wonder pomegranate supplementation didn’t seem to affect oxidative stress in tissue samples taken from prostate cancer patients. But, of course, what we care about is whether it affects the cancer Itself.
The strongest evidence for the anticancer activity of pomegranates is said to come from studies on prostate cancer. Unfortunately, early promising results were not confirmed when they were actually put to the test. For example, daily pomegranate Intake was found in a randomized controlled trial to have no impact on PSA levels, a marker of tumor progression. And, indeed, a randomized, double-blind, placebo-controlled trial found essentially no difference when it came to prostate cancer disease progression.
They were banking on the anti-inflammatory activity of pomegranate juice to help, but again, that had been demonstrated in vitro. In people, a meta-analysis based on five randomized controlled trials published in 2016 concluded that pomegranate juice did not have a significant effect on C-reactive protein levels, a key marker of inflammation. If you look at the forest plot, though, you’ll see all five trials tended towards lower C-reactive protein levels such that the data combined almost reached statistical significance. And indeed, an updated meta-analysis published in 2020 based on seven studies did indeed get tipped over into significance, and found a significant drop in two other inflammatory markers as well.
Huh, okay. Well, maybe pomegranate juice could help in the control of inflammatory diseases after all. But you don’t know, until you put it to the test.
Osteoarthritis involves the degeneration of the cushioning cartilage within joints, particularly the knees. If you take some human osteoarthritic cartilage samples and drip on a pomegranate extract, you can show cartilage-protective effects. Here’s how much cartilage disintegration was happening at baseline. Add some inflammation, and cartilage breakdown triples, but then add more and more of this pomegranate extract, and you can calm things down. But again, that’s in a petri dish. How do we know that when we eat pomegranates, the active components actually get into our bloodstream so they can find their way into our joints? Cartilage-protecting components were found to be bioavailable (at least in rabbits), raising the possibility that pomegranates could be a safe and nontoxic treatment with no side effects––as opposed to the drugs currently in use. But is it effective?
Clinical trials are in progress, and so many questions will be answered…right now! The first and only clinical trial to date on pomegranate juice and osteoarthritis. It’s not a placebo-controlled trial, but instead randomized people to pomegranate juice or nothing at all. Those drinking the juice did report less stiffness and impairment of physical function, but not significantly better than just doing nothing. Shoot.
But just as I was about to give up on pomegranates, I saw this study: Consumption of a pomegranate extract suppresses joint damage in rheumatoid arthritis. But no, it was just the POM ‘Not-So-Wonderful’ company inducing joint damage in a mouse as a model of rheumatoid arthritis. Come on!
What about this open-labeled study, where the patients knew what they were getting? Eight people with active rheumatoid arthritis took some pomegranate extract every day, and the six who stuck with it reported fewer tender joints. But as we learned from the osteoarthritis study, if you don’t have a control group you have no sense of what role, if any, the treatment actually plays.
And so finally, we come to this: a randomized, double-blind, placebo-controlled trial. It’s about time! Half of the subjects unknowingly got some pomegranate extracts; the other half unknowingly got the equivalent of a sugar pill and…significant improvement in the number of swollen joints, tender joints, pain intensity, a disease activity score, a health assessment questionnaire, and morning stiffness, compared to placebo. So, if you have rheumatoid arthritis, I would indeed recommend you start eating pomegranates. Why not just pop pomegranate pills? After all, it was a pomegranate extract that alleviated disease activity. One good reason to stick to the fruit is that when 19 pomegranate supplements were actually tested in a laboratory, most didn’t actually appear to have any pomegranate in them at all! Only 6 out of 19 appeared to be authentic.
Please consider volunteering to help out on the site.
- POM Wonderful, LLC v. Federal Trade Commission, 777 F.3d 478 (D.C. Cir. 2015)
- Sorvino C. The Verdict: POM Wonderful Misled Its Customers, A Blow To Its Billionaire Owners. Forbes. May 2, 2016.
- Court Mostly Backs FTC vs. Pomegranate Claims. Tufts Health & Nutrition Letter. March 11, 2015.
- Viuda-Martos M, Fernández-López J, Pérez-Álvarez JA. Pomegranate and its many functional components as related to human health: a review. Compr Rev Food Sci Food Saf. 2010;9(6):635-54.
- Gheflati A, Mohammadi M, Ramezani-Jolfaie N, Heidari Z, Salehi-Abargouei A, Nadjarzadeh A. Does pomegranate consumption affect weight and body composition? A systematic review and meta-analysis of randomized controlled clinical trials. Phytother Res. 2019;33(5):1277-88.
- Vlachojannis C, Erne P, Schoenenberger AW, Chrubasik-Hausmann S. A critical evaluation of the clinical evidence for pomegranate preparations in the prevention and treatment of cardiovascular diseases. Phytother Res. 2015;29(4):501-8.
- Forest CP, Padma-Nathan H, Liker HR. Efficacy and safety of pomegranate juice on improvement of erectile dysfunction in male patients with mild to moderate erectile dysfunction: a randomized, placebo-controlled, double-blind, crossover study. Int J Impot Res. 2007;19(6):564-7.
- Huang H, Liao D, Chen G, Chen H, Zhu Y. Lack of efficacy of pomegranate supplementation for glucose management, insulin levels and sensitivity: evidence from a systematic review and meta-analysis. Nutr J. 2017;16(1):67.
- Cerdá B, Soto C, Albaladejo MD, et al. Pomegranate juice supplementation in chronic obstructive pulmonary disease: a 5-week randomized, double-blind, placebo-controlled trial. Eur J Clin Nutr. 2006;60(2):245-53.
- Morvaridzadeh M, Sepidarkish M, Daneshzad E, Akbari A, Mobini GR, Heshmati J. The effect of pomegranate on oxidative stress parameters: A systematic review and meta-analysis. Complement Ther Med. 2020;48:102252.
- Cerdá B, Espín JC, Parra S, Martínez P, Tomás-Barberán FA. The potent in vitro antioxidant ellagitannins from pomegranate juice are metabolised into bioavailable but poor antioxidant hydroxy-6H-dibenzopyran-6-one derivatives by the colonic microflora of healthy humans. Eur J Nutr. 2004;43(4):205-20.
- Freedland SJ, Carducci M, Kroeger N, et al. A double-blind, randomized, neoadjuvant study of the tissue effects of POMx pills in men with prostate cancer before radical prostatectomy. Cancer Prev Res (Phila). 2013;6(10):1120-7.
- Turrini E, Ferruzzi L, Fimognari C. Potential effects of pomegranate polyphenols in cancer prevention and therapy. Oxid Med Cell Longev. 2015;2015:938475.
- Paller CJ, Pantuck A, Carducci MA. A review of pomegranate in prostate cancer. Prostate Cancer Prostatic Dis. 2017;20(3):265-70.
- Stenner-Liewen F, Liewen H, Cathomas R, et al. Daily pomegranate intake has no impact on psa levels in patients with advanced prostate cancer - results of a phase iib randomized controlled trial. J Cancer. 2013;4(7):597-605.
- Pantuck AJ, Pettaway CA, Dreicer R, et al. A randomized, double-blind, placebo-controlled study of the effects of pomegranate extract on rising PSA levels in men following primary therapy for prostate cancer. Prostate Cancer Prostatic Dis. 2015;18(3):242-8.
- Sahebkar A, Gurban C, Serban A, Andrica F, Serban M-C. Effects of supplementation with pomegranate juice on plasma C-reactive protein concentrations: A systematic review and meta-analysis of randomized controlled trials. Phytomedicine. 2016;23(11):1095-102.
- Wang P, Zhang Q, Hou H, et al. The effects of pomegranate supplementation on biomarkers of inflammation and endothelial dysfunction: A meta-analysis and systematic review. Complement Ther Med. 2020;49:102358.
- Danesi F, Ferguson LR. Could pomegranate juice help in the control of inflammatory diseases? Nutrients. 2017;9(9):E958.
- Ghoochani N, Karandish M, Mowla K, Haghighizadeh MH, Jalali MT. The effect of pomegranate juice on clinical signs, matrix metalloproteinases and antioxidant status in patients with knee osteoarthritis. J Sci Food Agric. 2016;96(13):4377-81.
- Ahmed S, Wang N, Hafeez BB, Cheruvu VK, Haqqi TM. Punica granatum L. extract inhibits IL-1beta-induced expression of matrix metalloproteinases by inhibiting the activation of MAP kinases and NF-kappaB in human chondrocytes in vitro. J Nutr. 2005;135(9):2096-102.
- Shukla M, Gupta K, Rasheed Z, Khan KA, Haqqi TM. Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1beta-induced PGE2 production in human chondrocytes in vitro. J Inflamm (Lond). 2008;5:9.
- Rasheed Z. Intake of pomegranate prevents the onset of osteoarthritis: molecular evidences. Int J Health Sci (Qassim). 2016;10(2):V-VIII.
- Shukla M, Gupta K, Rasheed Z, Khan KA, Haqqi TM. Consumption of hydrolyzable tannins-rich pomegranate extract suppresses inflammation and joint damage in rheumatoid arthritis. Nutrition. 2008;24(7-8):733-43.
- Balbir-Gurman A, Fuhrman B, Braun-Moscovici Y, Markovits D, Aviram M. Consumption of pomegranate decreases serum oxidative stress and reduces disease activity in patients with active rheumatoid arthritis: a pilot study. Isr Med Assoc J. 2011;13(8):474-9.
- Ghavipour M, Sotoudeh G, Tavakoli E, Mowla K, Hasanzadeh J, Mazloom Z. Pomegranate extract alleviates disease activity and some blood biomarkers of inflammation and oxidative stress in Rheumatoid Arthritis patients. Eur J Clin Nutr. 2017;71(1):92-6.
- Vlachojannis C, Zimmermann BF, Chrubasik-Hausmann S. Efficacy and safety of pomegranate medicinal products for cancer. Evid Based Complement Alternat Med. 2015;2015:258598.
- Madrigal-Carballo S, Rodriguez G, Krueger CG, Dreher M, Reed JD. Pomegranate (Punica granatum) supplements: Authenticity, antioxidant and polyphenol composition. J Funct Foods. 2009;1(3):324-9.
Motion graphics by Avo Media
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Title
Pomegranate: A Natural Treatment for Rheumatoid Arthritis
LicenseCreative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
Content URLDoctor's Note
I previously reported on POM Wonderful back in 2011 in my video Is Pomegranate Juice That Wonderful?. My other video on this fruit is Pomegranate vs. Placebo for Prostate Cancer.
What’s one way you can eat them? Check out my cooking video for Cran-Chocolate Pomegranate BROL Bowl.
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