Curcumin-free turmeric, from which the so-called active ingredient has been removed, may be as effective or even more potent.
Turmeric or Curcumin: Plants vs. Pills
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Supplement manufacturers often fall into the same reductionist trap as the drug companies. Herbs are assumed to have only one main active ingredient; and so, if you can isolate it and purify it into a pill, the thinking goes, you can boost the effects. Curcumin is described as the active ingredient in turmeric, but is it the active ingredient or just an active ingredient? It’s just one of many different components of the whole food spice.
Only limited studies have compared the potential of turmeric with curcumin, but some suggest turmeric, the whole food, may work even better, and not just against colon cancer cells. This group of researchers at the Anderson Cancer Center in Texas pitted curcumin against seven different types of human cancer cells. And also, turmeric.
Curcumin kicks butt against breast cancer cells, but turmeric, the whole food, kicks even more butt. Curcumin against pancreatic cancer; turmeric against pancreatic cancer, colon cancer, multiple myeloma, myelogenous leukemia, and more colorectal cancer. They found that turmeric was more potent compared to curcumin, suggesting that components other than curcumin can also contribute to anti-cancer activities.
Most clinical studies treating diseases in people have used curcumin supplements, as opposed to turmeric. But none have tried using turmeric components other than curcumin. But see, even curcumin-free turmeric exhibits anti-inflammatory and anticancer activities.
Although curcumin is believed to account for most activities of turmeric, research over the past decade has indicated that curcumin-free turmeric—turmeric with the so-called active ingredient removed—is as effective as, or even more effective than, curcumin-containing turmeric. There are turmerones, for example, in turmeric, but processed out of curcumin supplements, which may exhibit both anticancer activities as well as anti-inflammatory activities. So, I assumed this review would conclude, let’s give people turmeric; but instead, they were like, let’s make all sorts of different turmeric-derived supplements!
To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video. This is just an approximation of the audio contributed by Katie Schloer.
Please consider volunteering to help out on the site.
- S C Gupta, B Sung, J H Kim, S Prasad, S Li, B B Aggarwal. Multitargeting by turmeric, the golden spice: From kitchen to clinic. Mol Nutr Food Res. 2013 Sep;57(9):1510-28.
- K A Agarwal, C D Tripathi, B B Agarwal, S Saluja. Efficacy of turmeric (curcumin) in pain and postoperative fatigue after laparoscopic cholecystectomy: a double-blind, randomized placebo-controlled study. Surg Endosc. 2011 Dec;25(12):3805-10.
- J H Kim, S C Gupta, B Park, V R Yadav, B B Aggarwal. Turmeric (Curcuma longa) inhibits inflammatory nuclear factor (NF)-κB and NF-κB-regulated gene products and induces death receptors leading to suppressed proliferation, induced chemosensitization, and suppressed osteoclastogenesis. Mol Nutr Food Res. 2012 Mar;56(3):454-65.
- B B Aggarwal, W Yuan, S Li, S C Gupta. Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of turmeric. Mol Nutr Food Res. 2013 Sep;57(9):1529-42.
- I Hoffman. Transcending reductionism in nutrition research. Am J Clin Nutr. 2003 Sep;78(3 Suppl):514S-516S.
Image thanks to melpomen via 123rf
Supplement manufacturers often fall into the same reductionist trap as the drug companies. Herbs are assumed to have only one main active ingredient; and so, if you can isolate it and purify it into a pill, the thinking goes, you can boost the effects. Curcumin is described as the active ingredient in turmeric, but is it the active ingredient or just an active ingredient? It’s just one of many different components of the whole food spice.
Only limited studies have compared the potential of turmeric with curcumin, but some suggest turmeric, the whole food, may work even better, and not just against colon cancer cells. This group of researchers at the Anderson Cancer Center in Texas pitted curcumin against seven different types of human cancer cells. And also, turmeric.
Curcumin kicks butt against breast cancer cells, but turmeric, the whole food, kicks even more butt. Curcumin against pancreatic cancer; turmeric against pancreatic cancer, colon cancer, multiple myeloma, myelogenous leukemia, and more colorectal cancer. They found that turmeric was more potent compared to curcumin, suggesting that components other than curcumin can also contribute to anti-cancer activities.
Most clinical studies treating diseases in people have used curcumin supplements, as opposed to turmeric. But none have tried using turmeric components other than curcumin. But see, even curcumin-free turmeric exhibits anti-inflammatory and anticancer activities.
Although curcumin is believed to account for most activities of turmeric, research over the past decade has indicated that curcumin-free turmeric—turmeric with the so-called active ingredient removed—is as effective as, or even more effective than, curcumin-containing turmeric. There are turmerones, for example, in turmeric, but processed out of curcumin supplements, which may exhibit both anticancer activities as well as anti-inflammatory activities. So, I assumed this review would conclude, let’s give people turmeric; but instead, they were like, let’s make all sorts of different turmeric-derived supplements!
To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video. This is just an approximation of the audio contributed by Katie Schloer.
Please consider volunteering to help out on the site.
- S C Gupta, B Sung, J H Kim, S Prasad, S Li, B B Aggarwal. Multitargeting by turmeric, the golden spice: From kitchen to clinic. Mol Nutr Food Res. 2013 Sep;57(9):1510-28.
- K A Agarwal, C D Tripathi, B B Agarwal, S Saluja. Efficacy of turmeric (curcumin) in pain and postoperative fatigue after laparoscopic cholecystectomy: a double-blind, randomized placebo-controlled study. Surg Endosc. 2011 Dec;25(12):3805-10.
- J H Kim, S C Gupta, B Park, V R Yadav, B B Aggarwal. Turmeric (Curcuma longa) inhibits inflammatory nuclear factor (NF)-κB and NF-κB-regulated gene products and induces death receptors leading to suppressed proliferation, induced chemosensitization, and suppressed osteoclastogenesis. Mol Nutr Food Res. 2012 Mar;56(3):454-65.
- B B Aggarwal, W Yuan, S Li, S C Gupta. Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of turmeric. Mol Nutr Food Res. 2013 Sep;57(9):1529-42.
- I Hoffman. Transcending reductionism in nutrition research. Am J Clin Nutr. 2003 Sep;78(3 Suppl):514S-516S.
Image thanks to melpomen via 123rf
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Content URLDoctor's Note
That’s quite a rebut to reductionism. For more on this flawed nutritional philosophy, see my video Reductionism and the Deficiency Mentality.
Similar videos in this vein include:
- Food Antioxidants and Cancer
- Treating Asthma with Plants vs. Supplements?
- Broccoli: Sprouts vs. Supplements
- Industry Response to Plants Not Pills
Interested in learning more about turmeric and cancer? See:
- Back to Our Roots: Curry and Cancer
- Carcinogenic Blocking Effects of Turmeric
- Turmeric Curcumin Reprogramming Cancer Cell Death
- Turmeric Curcumin and Colon Cancer
- Topical Application of Turmeric Curcumin for Cancer
- Turmeric Curcumin, MGUS, and Multiple Myeloma
And for more on turmeric and everything else:
- Turmeric Curcumin and Rheumatoid Arthritis
- Turmeric Curcumin and Osteoarthritis
- Boosting the Bioavailability of Curcumin
- Who Shouldn’t Consume Curcumin or Turmeric?
- Preventing Alzheimer’s with Turmeric
- Treating Alzheimer’s with Turmeric
- Turmeric Curcumin and Pancreatic Cancer
- Turmeric Curcumin vs. Exercise for Artery Function
- Heart of Gold: Turmeric vs. Exercise
- Speeding Recovery from Surgery with Turmeric
- Benefits of Turmeric for Arsenic Exposure
- Benefits of Turmeric Curcumin for Inflammatory Orbital Pseudotumor
- Turmeric Curcumin for Prediabetes
- Fighting Lupus with Turmeric: Good as Gold
For all our videos on the latest research on turmeric, visit our Turmeric topic page.
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