The carotid arteries of those eating plant-based diets appear healthier than even those just as slim (long-distance endurance athletes who’ve run an average of 50,000 miles).
Arteries of Vegans vs. Runners
Below is an approximation of this video’s audio content. To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video.
We know from the work of Doctors Ornish and Esselstyn that switching to a plant-based diet can reverse heart disease, open up arteries—in some cases, without drugs, without surgery. But, because our first symptom of heart disease may be our last—sudden cardiac death—it’s best not to wait until atherosclerosis progresses that far.
To predict the risk of dying from a heart attack, sure, we can measure risk factors, such as cholesterol levels and blood pressure. But, wouldn’t it be nice to actually see what’s going on inside our arteries, before it’s too late? Well, our imaging technologies are so good now that we can. But, the required dose of radiation delivered to the chest is so high that a young woman getting just a single scan, for example, may increase her lifetime risk of breast cancer and lung cancer by between around 1 and 4%.
Our carotid arteries, though, which connect our heart to our brain, come close enough to the surface in our necks that we can visualize the arterial wall using harmless sound waves with ultrasound. Okay, so, how do the arteries of those eating plant-based diets compare to those eating the Standard American Diet? Researchers found some vegans, and found out.
Here’s the Standard American Diet group. This is the thickness of the inner wall of their carotid arteries, where the atherosclerotic plaque builds up—considered a predictor of “all-cause and cardiovascular mortality.” That same inner layer was significantly slimmer in vegans—but, so were the vegans themselves! Those eating the Standard American Diet were, on average, overweight, with a BMI over 26, while the vegans were a trim 21—that’s 36 pounds lighter, on average.
So, maybe the only reason those eating meat, eggs, and dairy had thickened arterial walls was because they were themselves overweight; maybe, the diet per se had nothing to do with it directly. To solve the riddle, one would have to find a group still eating the Standard American Diet, but as slim as a vegan.
To find a group that fit and trim in our society, they had to use long-distance endurance athletes—who ate the same crappy American diet, but ran an average of 48 miles per week for 21 years. You run almost two marathons a week for twenty years, you can be as slim as a vegan—no matter what you eat. So, where do they fall on the graph? Both the vegans and the conventional diet group were sedentary—less than an hour of exercise a week.
The endurance runners were here. So, it appears if you run an average of about a thousand miles a year, you can rival some couch potato vegans. Doesn’t mean you can’t do both, though, but it may be easier to just eat plants.
Please consider volunteering to help out on the site.
- A. Sarma, M. E. Heilbrun, K. E. Conner, S. M. Stevens, S. C. Woller, C. G. Elliott. Radiation and chest CT scan examinations: What do we know? Chest 2012 142(3):750 - 760.
- L. Fontana, T. E. Meyer, S. Klein, J. O. Holloszy. Long-term low-calorie low-protein vegan diet and endurance exercise are associated with low cardiometabolic risk. Rejuvenation Res. 2007 10(2):225 - 234.
- S.-Y. Yang, X.-J. Li, W. Zhang, C.-Q. Liu, H.-J. Zhang, J.-R. Lin, B. Yan, Y.-X. Yu, X.-L. Shi, C.-D. Li, W.-H. Li. Chinese lacto-vegetarian diet exerts favorable effects on metabolic parameters, intima-media thickness, and cardiovascular risks in healthy men. Nutr Clin Pract. 2012 27(3):392 - 398.
- T.-C. Su, P.-L. Torng, J.-S. Jeng, M.-F. Chen, C.-S. Liau. Arterial function of carotid and brachial arteries in postmenopausal vegetarians. Vasc Health Risk Manag 2011 7:517 - 523.
- T.-C. Su, J.-S. Jeng, Jung-Der Wang, P.-L. Torng, S.-J. Chang, C.-F. Chen, C.-S. Liau. Homocysteine, circulating vascular cell adhesion molecule and carotid atherosclerosis in postmenopausal vegetarian women and omnivores. Atherosclerosis 2006 184(2):356 - 362.
- A. D. Smith, H. Refsum. Do we need to reconsider the desirable blood level of vitamin B12? J. Intern. Med. 2012 271(2):179 - 182.
- L. M. Hurwitz, R. E. Reiman, T. T. Yoshizumi, P. C. Goodman, G. Toncheva, G. Nguyen, C. Lowry. Radiation dose from contemporary cardiothoracic multidetector CT protocols with an anthropomorphic female phantom: Implications for cancer induction. Radiology 2007 245(3):742 - 750.
- T. Kwok, P. Chook, L. Tam, M. Qiao, J. L. F. Woo, D. S. Celermajer, K. S. Woo. Vascular dysfunction in Chinese vegetarians: An apparent paradox? J. Am. Coll. Cardiol. 2005 46(10):1957 - 1958.
- T. Kwok, P. Chook, M. Qiao, L. Tam, Y. K. P. Poon, A. T. Ahuja, J. Woo, D. S. Celermajer, K. S. Woo. Vitamin B-12 supplementation improves arterial function in vegetarians with subnormal vitamin B-12 status. J Nutr Health Aging 2012 16(6):569 - 573.
- E. Mądry, A. Lisowska, P. Grebowiec, J. Walkowiak. The impact of vegan diet on B-12 status in healthy omnivores: Five-year prospective study. Acta Sci Pol Technol Aliment 2012 11(2):209 - 212.
- S. Murakami, K. Otsuka, N. Hotta, G. Yamanaka, Y. Kubo, O. Matsuoka, T. Yamanaka, M. Shinagawa, S. Nunoda, Y. Nishimura, K. Shibata, E. Takasugi, M. Nishinaga, M. Ishine, T. Wada, K. Okumiya, K. Matsubayashi, S. Yano, K. Ichihara, G. Cornélissen, F. Halberg. Common carotid intima-media thickness is predictive of all-cause and cardiovascular mortality in elderly community-dwelling people: Longitudinal Investigation for the Longevity and Aging in Hokkaido County (LILAC) study. Biomed. Pharmacother. 2005 59(Suppl 1):S49 - S53.
- Kong MH1, Fonarow GC, Peterson ED, Curtis AB, Hernandez AF, Sanders GD, Thomas KL, Hayes DL, Al-Khatib SM. Systematic review of the incidence of sudden cardiac death in the United States. J Am Coll Cardiol. 2011 15;57(7):794-801.
Images thanks to Coolmikeol, Nukamari, Lisaclarke, Marcos Vasconcelos Photography, massdistraction, and Rob Swatski via flickr; Christina Lohmeyer und Sasa Ilic (SUNBEAM VISION OHG) via Wikimedia; and bb4life_911 via Photobucket. Thanks to Ellen Reid for her image-finding expertise, and Jeff Thomas for his Keynote help.
Below is an approximation of this video’s audio content. To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video.
We know from the work of Doctors Ornish and Esselstyn that switching to a plant-based diet can reverse heart disease, open up arteries—in some cases, without drugs, without surgery. But, because our first symptom of heart disease may be our last—sudden cardiac death—it’s best not to wait until atherosclerosis progresses that far.
To predict the risk of dying from a heart attack, sure, we can measure risk factors, such as cholesterol levels and blood pressure. But, wouldn’t it be nice to actually see what’s going on inside our arteries, before it’s too late? Well, our imaging technologies are so good now that we can. But, the required dose of radiation delivered to the chest is so high that a young woman getting just a single scan, for example, may increase her lifetime risk of breast cancer and lung cancer by between around 1 and 4%.
Our carotid arteries, though, which connect our heart to our brain, come close enough to the surface in our necks that we can visualize the arterial wall using harmless sound waves with ultrasound. Okay, so, how do the arteries of those eating plant-based diets compare to those eating the Standard American Diet? Researchers found some vegans, and found out.
Here’s the Standard American Diet group. This is the thickness of the inner wall of their carotid arteries, where the atherosclerotic plaque builds up—considered a predictor of “all-cause and cardiovascular mortality.” That same inner layer was significantly slimmer in vegans—but, so were the vegans themselves! Those eating the Standard American Diet were, on average, overweight, with a BMI over 26, while the vegans were a trim 21—that’s 36 pounds lighter, on average.
So, maybe the only reason those eating meat, eggs, and dairy had thickened arterial walls was because they were themselves overweight; maybe, the diet per se had nothing to do with it directly. To solve the riddle, one would have to find a group still eating the Standard American Diet, but as slim as a vegan.
To find a group that fit and trim in our society, they had to use long-distance endurance athletes—who ate the same crappy American diet, but ran an average of 48 miles per week for 21 years. You run almost two marathons a week for twenty years, you can be as slim as a vegan—no matter what you eat. So, where do they fall on the graph? Both the vegans and the conventional diet group were sedentary—less than an hour of exercise a week.
The endurance runners were here. So, it appears if you run an average of about a thousand miles a year, you can rival some couch potato vegans. Doesn’t mean you can’t do both, though, but it may be easier to just eat plants.
Please consider volunteering to help out on the site.
- A. Sarma, M. E. Heilbrun, K. E. Conner, S. M. Stevens, S. C. Woller, C. G. Elliott. Radiation and chest CT scan examinations: What do we know? Chest 2012 142(3):750 - 760.
- L. Fontana, T. E. Meyer, S. Klein, J. O. Holloszy. Long-term low-calorie low-protein vegan diet and endurance exercise are associated with low cardiometabolic risk. Rejuvenation Res. 2007 10(2):225 - 234.
- S.-Y. Yang, X.-J. Li, W. Zhang, C.-Q. Liu, H.-J. Zhang, J.-R. Lin, B. Yan, Y.-X. Yu, X.-L. Shi, C.-D. Li, W.-H. Li. Chinese lacto-vegetarian diet exerts favorable effects on metabolic parameters, intima-media thickness, and cardiovascular risks in healthy men. Nutr Clin Pract. 2012 27(3):392 - 398.
- T.-C. Su, P.-L. Torng, J.-S. Jeng, M.-F. Chen, C.-S. Liau. Arterial function of carotid and brachial arteries in postmenopausal vegetarians. Vasc Health Risk Manag 2011 7:517 - 523.
- T.-C. Su, J.-S. Jeng, Jung-Der Wang, P.-L. Torng, S.-J. Chang, C.-F. Chen, C.-S. Liau. Homocysteine, circulating vascular cell adhesion molecule and carotid atherosclerosis in postmenopausal vegetarian women and omnivores. Atherosclerosis 2006 184(2):356 - 362.
- A. D. Smith, H. Refsum. Do we need to reconsider the desirable blood level of vitamin B12? J. Intern. Med. 2012 271(2):179 - 182.
- L. M. Hurwitz, R. E. Reiman, T. T. Yoshizumi, P. C. Goodman, G. Toncheva, G. Nguyen, C. Lowry. Radiation dose from contemporary cardiothoracic multidetector CT protocols with an anthropomorphic female phantom: Implications for cancer induction. Radiology 2007 245(3):742 - 750.
- T. Kwok, P. Chook, L. Tam, M. Qiao, J. L. F. Woo, D. S. Celermajer, K. S. Woo. Vascular dysfunction in Chinese vegetarians: An apparent paradox? J. Am. Coll. Cardiol. 2005 46(10):1957 - 1958.
- T. Kwok, P. Chook, M. Qiao, L. Tam, Y. K. P. Poon, A. T. Ahuja, J. Woo, D. S. Celermajer, K. S. Woo. Vitamin B-12 supplementation improves arterial function in vegetarians with subnormal vitamin B-12 status. J Nutr Health Aging 2012 16(6):569 - 573.
- E. Mądry, A. Lisowska, P. Grebowiec, J. Walkowiak. The impact of vegan diet on B-12 status in healthy omnivores: Five-year prospective study. Acta Sci Pol Technol Aliment 2012 11(2):209 - 212.
- S. Murakami, K. Otsuka, N. Hotta, G. Yamanaka, Y. Kubo, O. Matsuoka, T. Yamanaka, M. Shinagawa, S. Nunoda, Y. Nishimura, K. Shibata, E. Takasugi, M. Nishinaga, M. Ishine, T. Wada, K. Okumiya, K. Matsubayashi, S. Yano, K. Ichihara, G. Cornélissen, F. Halberg. Common carotid intima-media thickness is predictive of all-cause and cardiovascular mortality in elderly community-dwelling people: Longitudinal Investigation for the Longevity and Aging in Hokkaido County (LILAC) study. Biomed. Pharmacother. 2005 59(Suppl 1):S49 - S53.
- Kong MH1, Fonarow GC, Peterson ED, Curtis AB, Hernandez AF, Sanders GD, Thomas KL, Hayes DL, Al-Khatib SM. Systematic review of the incidence of sudden cardiac death in the United States. J Am Coll Cardiol. 2011 15;57(7):794-801.
Images thanks to Coolmikeol, Nukamari, Lisaclarke, Marcos Vasconcelos Photography, massdistraction, and Rob Swatski via flickr; Christina Lohmeyer und Sasa Ilic (SUNBEAM VISION OHG) via Wikimedia; and bb4life_911 via Photobucket. Thanks to Ellen Reid for her image-finding expertise, and Jeff Thomas for his Keynote help.
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Arteries of Vegans vs. Runners
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Content URLDoctor's Note
Did I say heart disease reversal? If you didn’t know there was a way to treat heart disease without getting your chest cracked open, then my blog post Heart disease: there is a cure is a good place to start.
For more on the radiation risks associated with diagnostic procedures, see Cancer Risk from CT Scan Radiation and Do Dental X-Rays Cause Brain Tumors?
Carotid artery wall thickness is what was measured in the study I profiled in Eggs vs. Cigarettes in Atherosclerosis.
Another comparison between athletes and plant-eaters can be found in Is It the Diet, the Exercise, or Both? It compares cancer-fighting abilities with a similar result. So you know what test they’re talking about, see my “prequel” video: Ex Vivo Cancer Proliferation Bioassay. For weight loss, diet also provides more control: Diet vs. Exercise for Weight Loss.
None of this is to disparage exercise, which is critical for a variety of important reasons: immunity (see Preserving Immune Function in Athletes with Nutritional Yeast), and breast health. So, diet and exercise, not or exercise. My physical activity comes from walking while I work: Standing Up for Your Health.
Not all studies have shown vegans have superior arterial form and function, though. Find out why in my next video, Vitamin B12 Necessary for Arterial Health.
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