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Lung Cancer Metastases and Broccoli

The anti-proliferative effects of cruciferous vegetable phytonutrients may decrease the metastatic potential of lung cancer, the number one cancer killer of women.

March 21, 2012 |
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Lung Cancer Metastases and Broccoli, 4.0 out of 5 based on 2 ratings

Sources Cited

Wu X, Zhu Y, Yan H, Liu B, Li Y, Zhou Q, Xu K. Isothiocyanates induce oxidative stress and suppress the metastasis potential of human non-small cell lung cancer cells. BMC Cancer. 2010 Jun 9;10:269.

Acknowledgements

Images thanks to Fir0002 via Wikimedia commons, http://tobaccodocuments.org and Health Canada.

Transcript

What else can broccoli do? Breast cancer is the most common cancer among women in the united states but lung is actually the #1 cancer killer of women. About 85% of women with breast cancer are still alive 5 years later, but ling cancer is picked up so late that the number’s reversed, 85% of lung cancer victims are dead. And 90% of those deaths are from metastases, the lung cancer spreading to other parts in the body.
Well broccoli seems to be able to do everything else, what about suppressing the metastatic potential of human lung cancer cells ? Check!
What they did to assess cancer cell migration is laid down a layer of cancer in a petri dish and then cut a swath down the middle. Within 24 hours, the cancer was creeping back, and by 30 hours closed the gap completely. Until, they start dripping some cruciferous compounds on them. As you can see the cancer cells seem almost paralyzed, stuck in place. They don’t seem to want to go anywhere, any time soon.
In their conclusion, they talk about the antiproliferative, antitumor activities of these broccoli family dietary compounds, ending with a word rarely seen in scholarly literature, since it’s just so nondescript, but in this case they evidently felt it necessary. These compounds have inhibitory effects on several types of cancer cell growth, such as leukemia, prostate cancer, breast cancer, lung cancer, cervical cancer, colorectal cancer, et., cetera.

To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring watch the above video. This is just an approximation of the audio contributed by veganmontreal.

To help out on the site please email volunteer@nutritionfacts.org

Dr. Michael Greger

Doctor's Note

This video is the tenth in a series on the latest research on cruciferous vegetables. There were two on kale, Kale and the Immune System and Smoking Versus Kale Juice. One on DNA protection (DNA Protection from Broccoli), two on breast cancer (Broccoli Versus Breast Cancer Stem Cells and Sulforaphane: From Broccoli to Breast), two on upper safety limits (Liver Toxicity Due to Broccoli Juice and How Much Broccoli Is Too Much?), one on detoxing (The Best Detox), and yesterday's video-of-the-day, Sometimes the Enzyme Myth Is True, on maximizing the production and absorption of sulforaphane, one of the key phytonutrients. There are past videos on greens and hundreds of other videos on more than a thousand subjects. Note that the paper I talk about in this video is open access, meaning you can download it for free by clicking on the link above in the Sources Cited section.

For some context, please also check out my associated blog posts: Breast Cancer Stem Cells vs. Broccoli and Fighting Inflammation with Food Synergy.

  • http://nutritionfacts.org/members/mgreger/ Michael Greger M.D.

    This video is the tenth in a series on the latest research on cruciferous vegetables. There were two on kale, Kale and the Immune System and Smoking Versus Kale Juice. One on DNA protection (DNA Protection from Broccoli), two on breast cancer (Broccoli Versus Breast Cancer Stem Cells and Sulforaphane: From Broccoli to Breast), two on upper safety limits (Liver Toxicity Due to Broccoli Juice and How Much Broccoli Is Too Much?), one on detoxing (The Best Detox), and yesterday’s video-of-the-day, Sometimes the Enzyme Myth Is True, on maximizing the production and absorption of sulforaphane, one of the key phytonutrients. There are past videos on greens and hundreds of other videos on more than a thousand subjects. Note that the paper I talk about in this video is open access, meaning you can download it for free by clicking on the link above in the Sources Cited section.

  • http://nutritionfacts.org/members/mike-quinoa/ Mike Quinoa

    Great video, etc. Yay broccoli! I’m showing this video to a friend of mine who smokes. If the picture of Barb Tarbox doesn’t scare him enough to quit, at least he’ll know he should adopt a plant-based diet.

  • http://nutritionfacts.org/members/valnaples/ valnaples

    Must say, I’ve been enjoying organic dino kale every day…raw, in lentil soup, toasted in oven…broccoli too is one of my favorites. But I think I need to pay more attention to the broccoli after watching Dr. Greger’s awesome videos!

  • http://nutritionfacts.org/members/dontlietomoman/ Dontlietomoman

    We love your site. Thanks for all the info and your efforts. My question is; Are Sulforaphane supplements of any value?

  • http://nutritionfacts.org/members/zoza/ zoza

    i hope be friend of you i study in since collage depart biochemistry and nutrition

  • Michael Greger M.D.

    For some context, please also check out my associated blog post Breast Cancer Stem Cells vs. Broccoli!

  • http://www.facebook.com/bruce.gray.710 Bruce Gray

    Don’t mean to be the cynic about anti-cancer foods, but afaik none helped Steve Jobs or Lance Armstrong.

  • Len

    When you liquify broccoli and other green leafy in a high speed blender do you lose some of the fiber ?

    • Toxins

       The fiber is indeed altered. Liquifying tends to destroy the fibers.

  • Just Curious

    Is all cooked animal protein carcinogenic? If so, this is news to me. I thought only grilled meats had that potential.

  • Joanna

    Thank you for building this website – it provides a wealth of information. My mother in lawhas a lung cancer that has not yet metastasized. She also has diabetes. What are 5 things you would recommend her to eat daily that you believe would help? Also, what are your thoughts on blending for better nutrient absorbtion?

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