Those who eat meat risk food poisoning from undercooked meat, but also exposure to cooked meat carcinogens in well-cooked meat. By boiling meat, non-vegetarians can mediate their risk of both.
Reducing Cancer Risk in Meat-Eaters
Below is an approximation of this video’s audio content. To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video.
The cooked meat carcinogens implicated in promoting the initiation, growth, and spread of breast cancer may also increase the risk of prostate cancer. The mechanism through which the consumption of well-done meat may increase prostate cancer risk is via the release of mutagenic compounds during cooking. The heterocyclic amines and polycyclic aromatic hydrocarbons are chemicals formed when the muscles of mammals, fish, or birds are cooked by high-temperature methods, such as pan-frying or barbecuing.
And, in chicken, we just found out the temperature doesn’t have to be that high. Just baking at about 350 for 15 minutes leads to significant production of heterocyclic amines, including PHiP. So, it’s not just frying, and grilling, and barbecuing.
These cooked meat carcinogens have also recently been associated with increased risk of kidney cancer, colon cancer, lung cancer, and pancreatic cancer—which is not a cancer we want to get. How do we decrease our exposure to these potent mutagens? Well, fried bacon and fish are the worst. Interestingly, chicken without skin had higher mutagen levels than with skin, which may act “as an insulating layer for the meat.”
Now, medium rare is less mutagenic than well done, which may be why women in the Iowa Women’s Health Study who consumed meat very well done appeared to have nearly five times higher risk for breast cancer than that of women who consumed meat “rare or medium done.”
But, this raises the so-called “paradox” of preparing meat, noted by the Harvard Health Letter. Well-cooked, and you risk cancer; undercooked, and risk E. coli. Eating boiled meat—not broiled, but boiled in water—is probably the safest.
If you eat meat that never goes above 212 degrees Fahrenheit, both your urine and feces are significantly less mutagenic, compared to eating meat cooked at higher temperatures—meaning you have less DNA-damaging substances flowing through your bloodstream, and coming in contact with your colon.
Please consider volunteering to help out on the site.
- Holland RD, Gehring T, Taylor J, Lake BG, Gooderham NJ, Turesky RJ. Formation of a mutagenic heterocyclic aromatic amine from creatinine in urine of meat eaters and vegetarians. Chem. Res. Toxicol. 2005 18(3):579 - 590
- Turesky RJ. Formation and biochemistry of carcinogenic heterocyclic aromatic amines in cooked meats. Toxicol. Lett. 2007 168(3):219 - 227
- Bessette EE, Yasa I, Dunbar D, Wilkens LR, Le Marchand L, Turesky RJ. Biomonitoring of carcinogenic heterocyclic aromatic amines in hair: A validation study. Chem. Res. Toxicol. 2009 22(8):1454 - 1463
- Magagnotti C, Orsi F, Bagnati R, Celli D, Rotilio D, Fanelli R, Airoldi L. Effect of diet on serum albumin and hemoglobin adducts of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in humans. Int. J. Cancer: 88, 1 6 2000 88(NA):1-6
- Zheng W, Gustafson DR, Sinha R, Cerhan JR, Moore D, Hong CP, Anderson KE, Kushi LH, Sellers TA, Folsom AR. Well-done meat intake and the risk of breast cancer. J Natl Cancer Inst. 1998 Nov 18;90(22):1724-9.
- Zaidi R, Kumar S, Rawat PR. Rapid detection and quantification of dietary mutagens in food using mass spectrometry and ultra performance liquid chromatography. Food Chem. 2012;135(4):2897-903.
Images thanks to thetejon, Austin Keys, and Paul-W via flickr
- alimentación a base de vegetales
- aminas heterocíclicas
- bacterias fecales
- cáncer
- cáncer de colon
- cáncer de mama
- cáncer de páncreas
- cáncer de próstata
- cáncer de pulmón
- cáncer de riñon
- carcinógenos
- carne
- carne de cerdo
- carne de res
- contaminación fecal
- daño al ADN
- E. coli
- enfermedad renal
- enfermedad transmitida a través de los alimentos
- estrés oxidativo
- Harvard
- hidrocarburos aromáticos policíclicos
- intoxicación por alimentos
- métodos de cocción
- pavo
- pescado
- PhIP
- pollo
- productos avícolas
- productos de origen animal
- proteína de origen animal
- salud de la mujer
- salud del colon
- salud del páncreas
- salud mamaria
- salud masculina
- salud pulmonar
- supervivencia al cáncer
- tocino
- veganos
- vegetarianos
Below is an approximation of this video’s audio content. To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video.
The cooked meat carcinogens implicated in promoting the initiation, growth, and spread of breast cancer may also increase the risk of prostate cancer. The mechanism through which the consumption of well-done meat may increase prostate cancer risk is via the release of mutagenic compounds during cooking. The heterocyclic amines and polycyclic aromatic hydrocarbons are chemicals formed when the muscles of mammals, fish, or birds are cooked by high-temperature methods, such as pan-frying or barbecuing.
And, in chicken, we just found out the temperature doesn’t have to be that high. Just baking at about 350 for 15 minutes leads to significant production of heterocyclic amines, including PHiP. So, it’s not just frying, and grilling, and barbecuing.
These cooked meat carcinogens have also recently been associated with increased risk of kidney cancer, colon cancer, lung cancer, and pancreatic cancer—which is not a cancer we want to get. How do we decrease our exposure to these potent mutagens? Well, fried bacon and fish are the worst. Interestingly, chicken without skin had higher mutagen levels than with skin, which may act “as an insulating layer for the meat.”
Now, medium rare is less mutagenic than well done, which may be why women in the Iowa Women’s Health Study who consumed meat very well done appeared to have nearly five times higher risk for breast cancer than that of women who consumed meat “rare or medium done.”
But, this raises the so-called “paradox” of preparing meat, noted by the Harvard Health Letter. Well-cooked, and you risk cancer; undercooked, and risk E. coli. Eating boiled meat—not broiled, but boiled in water—is probably the safest.
If you eat meat that never goes above 212 degrees Fahrenheit, both your urine and feces are significantly less mutagenic, compared to eating meat cooked at higher temperatures—meaning you have less DNA-damaging substances flowing through your bloodstream, and coming in contact with your colon.
Please consider volunteering to help out on the site.
- Holland RD, Gehring T, Taylor J, Lake BG, Gooderham NJ, Turesky RJ. Formation of a mutagenic heterocyclic aromatic amine from creatinine in urine of meat eaters and vegetarians. Chem. Res. Toxicol. 2005 18(3):579 - 590
- Turesky RJ. Formation and biochemistry of carcinogenic heterocyclic aromatic amines in cooked meats. Toxicol. Lett. 2007 168(3):219 - 227
- Bessette EE, Yasa I, Dunbar D, Wilkens LR, Le Marchand L, Turesky RJ. Biomonitoring of carcinogenic heterocyclic aromatic amines in hair: A validation study. Chem. Res. Toxicol. 2009 22(8):1454 - 1463
- Magagnotti C, Orsi F, Bagnati R, Celli D, Rotilio D, Fanelli R, Airoldi L. Effect of diet on serum albumin and hemoglobin adducts of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in humans. Int. J. Cancer: 88, 1 6 2000 88(NA):1-6
- Zheng W, Gustafson DR, Sinha R, Cerhan JR, Moore D, Hong CP, Anderson KE, Kushi LH, Sellers TA, Folsom AR. Well-done meat intake and the risk of breast cancer. J Natl Cancer Inst. 1998 Nov 18;90(22):1724-9.
- Zaidi R, Kumar S, Rawat PR. Rapid detection and quantification of dietary mutagens in food using mass spectrometry and ultra performance liquid chromatography. Food Chem. 2012;135(4):2897-903.
Images thanks to thetejon, Austin Keys, and Paul-W via flickr
- alimentación a base de vegetales
- aminas heterocíclicas
- bacterias fecales
- cáncer
- cáncer de colon
- cáncer de mama
- cáncer de páncreas
- cáncer de próstata
- cáncer de pulmón
- cáncer de riñon
- carcinógenos
- carne
- carne de cerdo
- carne de res
- contaminación fecal
- daño al ADN
- E. coli
- enfermedad renal
- enfermedad transmitida a través de los alimentos
- estrés oxidativo
- Harvard
- hidrocarburos aromáticos policíclicos
- intoxicación por alimentos
- métodos de cocción
- pavo
- pescado
- PhIP
- pollo
- productos avícolas
- productos de origen animal
- proteína de origen animal
- salud de la mujer
- salud del colon
- salud del páncreas
- salud mamaria
- salud masculina
- salud pulmonar
- supervivencia al cáncer
- tocino
- veganos
- vegetarianos
Comparte "Reducing Cancer Risk in Meat-Eaters"
Puedes compartir este material en la red o impreso bajo nuestra licencia Creative Commons. Deberás atribuir el artículo a NutritionFacts.org y agregar la liga a nuestro sitio en tu publicación
Si se realizan cambios en el texto o video original, se debe indicar, razonablemente, lo que ha cambiado en relación con el artículo o el video.
No se puede usar nuestro contenido para propósitos comerciales.
No puede aplicar términos legales o medidas tecnológicas que restrinjan a otros a hacer cualquier cosa permitida aquí.
Si tienes alguna duda, por favor Contáctanos
Reducing Cancer Risk in Meat-Eaters
LicenciaCreative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
URLNota del Doctor
Animal products may also increase prostate cancer risk through other mechanisms (see The Answer to the Pritikin Puzzle, and Cancer Reversal Through Diet?).
A similar study where they compared the excretion of carcinogens formed in processed meats can be found in Prevention is Better than Cured Meat.
Oh, and if there are carcinogens in roasted chicken, what about roasted coffee? See Coffee & Cancer.
In Estrogenic Cooked Meat Carcinogens, I showed that these cooked meat carcinogens may stimulate breast cancer cell growth nearly as much as pure estrogen. In PhIP: The Three Strikes Breast Carcinogen, I showed that these chemicals may promote breast cancer invasiveness even more than estrogen. In Heterocyclic Amines in Eggs, Cheese, & Creatine?, I explore how even those eating vegetarian may be exposed to these compounds.
Also, be sure to check out my associated blog posts for additional context: Avoiding Cooked Meat Carcinogens, and Foods that May Block Cancer Formation.
Si no lo has hecho aún, puedes suscribirte a mis videos de forma gratuita haciendo click aquí. Lee esta información importante sobre las traducciones aquí.