Inhibiting mTOR with Rapamycin for Extending Lifespan and Healthspan
Rapamycin appears to be a universal anti-aging drug, extending the lifespan of all animals tested to date; it’s the only known drug to do so.
Topic summary contributed by volunteer(s): Andrew
Penicillin, the first antibiotic, was discovered from bread mold. Since its discovery, many miraculous antibiotics have been developed, but are we coming to the end of an era? Certain antibiotic infections used to only develop and be transmitted in hospitals, but not anymore. It turns out that livestock may consume nearly 80% of the antibiotics in the USA. This may then create the antibiotic resistant superbugs such as MRSA, Yersinia, and Staph, that are now found in a significant portion of store bought meat, and that kill 23, 000 Americans every year. Seems a high price to pay to save a penny per pound at the till.
Normal cooking can kill some, but not all, of these superbugs, and cross-contamination may lead to infection regardless of how well the meat is cooked. Certain E. coli infections of the gut may lead to urinary tract infections (UTI’s) that may indirectly increase the risk of breast cancer because treatment with antibiotics can wipe out beneficial gut bacteria. Disrupting the delicate balance of the gut microbiome may also lead to weight gain and diarrhea. Drugs like antibiotics have been considered one possible explanation for the link between chicken consumption and other cancers. Cranberry juice seems to be protective against UTI’s and owning a dog may reduce the risk of ear infections in children and in doing so may reduce antibiotic exposure..
Evidence based medicine is finally doing away with the neutropenic diet for cancer patients, but is there a diet we should follow? In one study, organic meat seems to be slightly less contaminated than traditional, and may also have lower proportion of MDR bacteria. Antibiotics may not be the only drugs (or heavy metals) we’re getting with meat. A vegetarian diet may lower the levels of antibiotics in people not actually taking antibiotics. White meat of chicken may contain more antibiotics than dark meat. Using antiseptic mouthwash may inhibit your athletic prowess; swishing with green tea is a good alternative.
For substantiation of any statements of fact from the peer-reviewed medical literature, please see the associated videos below.
Image Credit: Pixabay. This image has been modified.
Rapamycin appears to be a universal anti-aging drug, extending the lifespan of all animals tested to date; it’s the only known drug to do so.
Probiotics can actually interfere with microbiome recovery after antibiotics, rather than facilitate it.
Randomized controlled trials have found that pneumonia vaccines significantly reduce the risk of pneumococcal pneumonia in people 65 and older.
Why do some populations retain their hearing into old age?
I go over randomized, controlled trials and case reports of stool transplants for various clinical conditions.
I go over a case report of water-only fasting, followed by a whole food, plant-based diet for follicular lymphoma.
Tainted chicken may result in more than a million urinary tract infections in American women every year.
Those eating plant-based have a reduced load of antibiotic resistance genes in their gut.
What food can eradicate H. pylori in the majority of patients?
What explains the Achilles’ heel in certain Asian diets?
Even if we could accurately diagnose SIBO, if there is no difference in symptoms between those testing positive and those testing negative, then what’s the point?
More than 95 percent of human exposure to industrial pollutants like dioxins and PCBs comes from fish, other meat, and dairy.
Miracle drug antibiotics are being squandered to compensate for the overcrowded, stressful, unhygienic conditions on factory farms.
How to treat the cause by preventing the emergence of pandemic viruses in the first place (a video I recorded more than a decade ago when I was Public Health Director at the HSUS in Washington DC).
What would happen within just two weeks if you swapped the diets of Americans with that of healthier eaters?
A low-fiber diet is a key driver of microbiome depletion, the disappearance of diversity in our good gut flora.
Given their oxalate content, how much is too much spinach, chard, beet greens, chaga mushroom powder, almonds, cashews, star fruit, and instant tea?
Even though dietary oxalates may have a limited effect on kidney stone risk in most people, there are some predisposing factors that can put anyone at risk.
Comparing contamination rates for antibiotic-resistant E. coli and ExPEC bacteria that cause urinary tract infections
A 5% tea-tree oil gel is pitted head-to-head against the leading over-the-counter treatment for pimples.
What role do antibiotics play in the development and treatment of autism spectrum disorder?
We shouldn’t ever swallow aloe vera, but how does using it topically for a chronic inflammatory autoimmune disease compare to steroids?
Commercial influences may have corrupted the American College of Sports Medicine’s hydration guidelines.
Is testing for body burden of heavy metals like mercury with “urine mobilization tests,” “challenge tests,” and “provoked urine tests” just a scam?
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The amount of beta-glucan fiber in just a dusting of nutritional yeast a day is put to the test in a randomized, double-blind, placebo-controlled trial for the prevention of common childhood illnesses.
In certain medical conditions, probiotic supplements may actually make things worse.
Should we be concerned about high-choline plant foods, such as broccoli, producing the same toxic TMAO that results from eating high-choline animal foods, such as eggs?
What happens when our crops are grown in soil contaminated with arsenic-based pesticides and arsenic drug-laced chicken manure?
What was the National Chicken Council’s response to public health authorities calling for the industry to stop feeding arsenic-based drugs to poultry?
One way a diet rich in animal-sourced foods like meat, eggs, and cheese may contribute to heart disease, stroke, kidney failure, and death is through the production of toxin called TMAO.
Given the role our gut bacteria can play in affecting our weight, having family and friends who are obese may not just be socially contagious, but actually contagious.
How the egg industry funded a study designed to cover up the toxic trimethylamine oxide reaction to egg consumption.
Immunocompromised patients, such as those undergoing chemotherapy, are often denied fresh fruits and vegetables to ostensibly protect them against foodborne illness.
Organic food consumption appears to reduce exposure to pesticide residues and antibiotic-resistant bacteria.
Why does the United States appear to have the highest level of C. diff contamination of the meat supply?
Beta glucan fiber in nutritional yeast may improve immune function, but there is a concern about lead contamination in some brands.
The FDA’s suggestion that the meat industry voluntarily stop feeding antibiotics by the ton to farm animals to fatten them faster falls short of the changes needed to forestall the epidemic of antibiotic resistance.
The emergence of pathogens resistant to even our antibiotics of last resort has raised the specter of a “post-antibiotic age” in which drugs to fight infections may be useless. This has focused attention on the mass use of antibiotics in farm animal feed to promote growth and prevent infection in high density production.
By testing chicken feathers for chemical residues, researchers aim to find out what the poultry industry is feeding their birds. The presence of banned drugs and a broad range of pharmaceuticals raises concern, recalling the time in which DES was fed to chickens for years after it was shown to cause human vagina cancer.