Test tube studies show advantages of organic produce, such as better cancer cell growth suppression, but what about in people, not Petri dishes?
Are Organic Foods Healthier?
The medical literature has been historically hostile to organic foods, blaming, in part, erroneous information supplied by the health food movement for our ignorance of nutrition, but until a few generations ago, all food was organic. So it’s kind of ironic that what we now call conventional food really isn’t very conventional for our species.
By eating organic we can reduce our exposure to pesticides, but it remains unclear whether such a reduction in exposure is clinically relevant. I talked about some of the test tube studies comparing health-related properties of organic vs. conventional foods—higher antioxidative and antimutagenic activity as well as better inhibition of cancer cell proliferation, but in terms of studies on actual people rather than Petri dishes, there isn’t much out there.
Why can’t you just compare the health of those who buy organic to those who don’t? Organic consumers do report being significantly healthier than conventional consumers, but organic consumers also tend to eat more plant foods in general, and less soda and alcohol, processed meat or milk, and just eat healthier in general, so no wonder they feel so much better.
Therefore, there is an urgent need for interventional trials, or studies following cohorts of people eating organic over time, like this one, the Million Women Study in the UK, the first to examine the association between the consumption of organic food and subsequent risk of cancer. The only significant risk reduction they found, though, was for non-Hodgkin’s lymphoma. This is consistent with data showing a higher risk of developing lymphoma in those who have higher levels of pesticides stored in their butt fat, which they looked at only because studies on farmworkers found higher rates of lymphoma.
Parental farmworker exposure is also associated with a birth defect of the penis called hypospadias, and so researchers decided to see if moms who failed to choose organic were at increased risk. And indeed, they found that frequent consumption of conventional high-fat dairy products was associated with about double the odds of the birth defect. This could just be because those who choose organic have other related healthy behaviors, or it could be that high-fat foods, like dairy products, bio-amplify the fat-soluble toxicants in our environment.
There are two other general population studies that have raised concerns: one that found about a 50% to 70% increase in the odds of ADHD among children with pesticide levels in their urine common among US children, and another that found triple the odds of testicular cancer among men with higher levels of organochlorine pesticides in their blood–90% of which comes from fish, meat, and dairy, which may help explain rising testicular cancer rates in many Western countries since World War II.
What about interventional trials? All we have in the medical literature so far are studies like this, showing organically grown food provides health benefits to fruit flies, raised on diets of conventional versus organic produce then subjected to a variety of tests designed to assess overall fly health. And what do you know, flies raised on diets made from organically grown produce lived longer. Hmm, insects eating insecticides don’t do as well. Not exactly much of a breakthrough.
To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video. This is just an approximation of the audio contributed by Katie Schloer.
Please consider volunteering to help out on the site.
- R W Grady. Are organic choices really better? J Urol. 2013 Mar;189(3):798-9.
- K E Bradbury , A Balkwill ,E A Spencer ,A W Roddam , G K Reeves , J Green ,T J Key , V Beral ,K Pirie ; Million Women Study Collaborators. Organic food consumption and the incidence of cancer in a large prospective study of women in the United Kingdom. Br J Cancer. 2014 Apr 29;110(9):2321-6.doi: 10.1038/bjc.2014.148. Epub 2014 Mar 27
- R Chhabra ,S Kolli , J H Bauer . Organically grown food provides health benefits to Drosophila melanogaster.PLoS One. 2013;8(1):e52988.doi: 10.1371/journal.pone.0052988. Epub 2013 Jan 9.
- E Kesse-Guyot , S Péneau , C Méjean , F Szabo de Edelenyi , P Galan ,S Hercberg ,D Lairon . Profiles of organic food consumers in a large sample of French adults: results from the Nutrinet-Santé cohort study.PLoS One. 2013 Oct 18;8(10):e76998.doi: 10.1371/journal.pone.0076998. eCollection 2013.
- A W Campbell . Organic vs conventional Altern Ther Health Med. 2012 Nov-Dec;18(6):8-9.
- J Forman ,J Silverstein. Organic foods: health and environmental advantages and disadvantages. Pediatrics. 2012 Nov;130(5):e1406-15. doi: 10.1542/peds.2012-2579. Epub 2012 Oct 22.
- M Barański , D Srednicka-Tober , N Volakakis , C Seal , R Sanderson ,G B Stewart ,C Benbrook , B Biavati ,E Markellou , C Giotis , J Gromadzka-Ostrowska , E Rembiałkowska , K Skwarło-Sońta ,R Tahvonen , D Janovská , U Niggli , P Nicot , C Leifert . Higher antioxidant and lower cadmium concentrations and lower incidence of pesticide residues in organically grown crops: a systematic literature review and meta-analyses. Br J Nutr. 2014 Sep 14;112(5):794-811.doi: 10.1017/S0007114514001366. Epub 2014 Jun 26.
- E V Bräuner , M Sørensen , E Gaudreau ,A LeBlanc , K T Eriksen ,A Tjønneland , K Overvad , O Raaschou-Nielsen . A prospective study of organochlorines in adipose tissue and risk of non Hodgkin lymphoma.Environ Health Perspect. 2012 Jan;120(1):105-11.
- J S Christensen , C Asklund ,N E Skakkebæk , N Jørgensen , H R Andersen , T M Jørgensen , L H Olsen , A P Høyer , J Moesgaard , J Thorup , T K Jensen ,J Urol. Association between organic dietary choice during pregnancy and hypospadias in offspring: a study of mothers of 306 boys operated on for hypospadias. 2013 Mar;189(3):1077-82. doi: 10.1016/j.juro.2012.09.116. Epub 2012 Oct 2.
- F Giannandrea ,L Gandini , D Paoli , R Turci , I Figà-Talamanca . Pesticide exposure and serum organochlorine residuals among testicular cancer patients and healthy controls.J Environ Sci Health B. 2011;46(8):780-7. doi: 10.1080/03601234.2012.597704.
- T H Jukes . The organic food myth.JAMA. 1974 Oct 14;230(2):276-7.
- M F Bouchard , D C Bellinger , R O Wright , M G Weisskopf . Attention-deficit/hyperactivity disorder and urinary metabolites of organophosphate pesticides. Pediatrics. 2010 Jun;125(6):e1270-7. doi: 10.1542/peds.2009-3058. Epub 2010 May 17.
- M Huber, E Rembiałkowska, D Średnicka, S Bügel, L P L Van De Vijver. Organic food and impact on human health: Assessing the status quo and prospects of research. NJAS-Wageningen Journal of Life Sciences 58.3 (2011): 103-109.
- E Rembiałkowska , K Renata, Ś Dominika, B Katarzyna, B Magdalena . Different aspects of organic and conventional food consumers lifestyle. New Medicine (2008).
Images thanks to heather_on3 / Flickr.
The medical literature has been historically hostile to organic foods, blaming, in part, erroneous information supplied by the health food movement for our ignorance of nutrition, but until a few generations ago, all food was organic. So it’s kind of ironic that what we now call conventional food really isn’t very conventional for our species.
By eating organic we can reduce our exposure to pesticides, but it remains unclear whether such a reduction in exposure is clinically relevant. I talked about some of the test tube studies comparing health-related properties of organic vs. conventional foods—higher antioxidative and antimutagenic activity as well as better inhibition of cancer cell proliferation, but in terms of studies on actual people rather than Petri dishes, there isn’t much out there.
Why can’t you just compare the health of those who buy organic to those who don’t? Organic consumers do report being significantly healthier than conventional consumers, but organic consumers also tend to eat more plant foods in general, and less soda and alcohol, processed meat or milk, and just eat healthier in general, so no wonder they feel so much better.
Therefore, there is an urgent need for interventional trials, or studies following cohorts of people eating organic over time, like this one, the Million Women Study in the UK, the first to examine the association between the consumption of organic food and subsequent risk of cancer. The only significant risk reduction they found, though, was for non-Hodgkin’s lymphoma. This is consistent with data showing a higher risk of developing lymphoma in those who have higher levels of pesticides stored in their butt fat, which they looked at only because studies on farmworkers found higher rates of lymphoma.
Parental farmworker exposure is also associated with a birth defect of the penis called hypospadias, and so researchers decided to see if moms who failed to choose organic were at increased risk. And indeed, they found that frequent consumption of conventional high-fat dairy products was associated with about double the odds of the birth defect. This could just be because those who choose organic have other related healthy behaviors, or it could be that high-fat foods, like dairy products, bio-amplify the fat-soluble toxicants in our environment.
There are two other general population studies that have raised concerns: one that found about a 50% to 70% increase in the odds of ADHD among children with pesticide levels in their urine common among US children, and another that found triple the odds of testicular cancer among men with higher levels of organochlorine pesticides in their blood–90% of which comes from fish, meat, and dairy, which may help explain rising testicular cancer rates in many Western countries since World War II.
What about interventional trials? All we have in the medical literature so far are studies like this, showing organically grown food provides health benefits to fruit flies, raised on diets of conventional versus organic produce then subjected to a variety of tests designed to assess overall fly health. And what do you know, flies raised on diets made from organically grown produce lived longer. Hmm, insects eating insecticides don’t do as well. Not exactly much of a breakthrough.
To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video. This is just an approximation of the audio contributed by Katie Schloer.
Please consider volunteering to help out on the site.
- R W Grady. Are organic choices really better? J Urol. 2013 Mar;189(3):798-9.
- K E Bradbury , A Balkwill ,E A Spencer ,A W Roddam , G K Reeves , J Green ,T J Key , V Beral ,K Pirie ; Million Women Study Collaborators. Organic food consumption and the incidence of cancer in a large prospective study of women in the United Kingdom. Br J Cancer. 2014 Apr 29;110(9):2321-6.doi: 10.1038/bjc.2014.148. Epub 2014 Mar 27
- R Chhabra ,S Kolli , J H Bauer . Organically grown food provides health benefits to Drosophila melanogaster.PLoS One. 2013;8(1):e52988.doi: 10.1371/journal.pone.0052988. Epub 2013 Jan 9.
- E Kesse-Guyot , S Péneau , C Méjean , F Szabo de Edelenyi , P Galan ,S Hercberg ,D Lairon . Profiles of organic food consumers in a large sample of French adults: results from the Nutrinet-Santé cohort study.PLoS One. 2013 Oct 18;8(10):e76998.doi: 10.1371/journal.pone.0076998. eCollection 2013.
- A W Campbell . Organic vs conventional Altern Ther Health Med. 2012 Nov-Dec;18(6):8-9.
- J Forman ,J Silverstein. Organic foods: health and environmental advantages and disadvantages. Pediatrics. 2012 Nov;130(5):e1406-15. doi: 10.1542/peds.2012-2579. Epub 2012 Oct 22.
- M Barański , D Srednicka-Tober , N Volakakis , C Seal , R Sanderson ,G B Stewart ,C Benbrook , B Biavati ,E Markellou , C Giotis , J Gromadzka-Ostrowska , E Rembiałkowska , K Skwarło-Sońta ,R Tahvonen , D Janovská , U Niggli , P Nicot , C Leifert . Higher antioxidant and lower cadmium concentrations and lower incidence of pesticide residues in organically grown crops: a systematic literature review and meta-analyses. Br J Nutr. 2014 Sep 14;112(5):794-811.doi: 10.1017/S0007114514001366. Epub 2014 Jun 26.
- E V Bräuner , M Sørensen , E Gaudreau ,A LeBlanc , K T Eriksen ,A Tjønneland , K Overvad , O Raaschou-Nielsen . A prospective study of organochlorines in adipose tissue and risk of non Hodgkin lymphoma.Environ Health Perspect. 2012 Jan;120(1):105-11.
- J S Christensen , C Asklund ,N E Skakkebæk , N Jørgensen , H R Andersen , T M Jørgensen , L H Olsen , A P Høyer , J Moesgaard , J Thorup , T K Jensen ,J Urol. Association between organic dietary choice during pregnancy and hypospadias in offspring: a study of mothers of 306 boys operated on for hypospadias. 2013 Mar;189(3):1077-82. doi: 10.1016/j.juro.2012.09.116. Epub 2012 Oct 2.
- F Giannandrea ,L Gandini , D Paoli , R Turci , I Figà-Talamanca . Pesticide exposure and serum organochlorine residuals among testicular cancer patients and healthy controls.J Environ Sci Health B. 2011;46(8):780-7. doi: 10.1080/03601234.2012.597704.
- T H Jukes . The organic food myth.JAMA. 1974 Oct 14;230(2):276-7.
- M F Bouchard , D C Bellinger , R O Wright , M G Weisskopf . Attention-deficit/hyperactivity disorder and urinary metabolites of organophosphate pesticides. Pediatrics. 2010 Jun;125(6):e1270-7. doi: 10.1542/peds.2009-3058. Epub 2010 May 17.
- M Huber, E Rembiałkowska, D Średnicka, S Bügel, L P L Van De Vijver. Organic food and impact on human health: Assessing the status quo and prospects of research. NJAS-Wageningen Journal of Life Sciences 58.3 (2011): 103-109.
- E Rembiałkowska , K Renata, Ś Dominika, B Katarzyna, B Magdalena . Different aspects of organic and conventional food consumers lifestyle. New Medicine (2008).
Images thanks to heather_on3 / Flickr.
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Are Organic Foods Healthier?
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Content URLDoctor's Note
For more on pesticide residues on produce, see my recent video Are Organic Foods Safer? For how to best get them off, see How to Make Your Own Fruit and Vegetable Wash. Pesticides are one thing, but Are Organic Foods More Nutritious?
That was the first in my five-part video series on organic foods, which ends tomorrow with the wrap-up: Are the Benefits of Organic Food Underrated or Overrated?
For more on the impact of food contaminants during pregnancy, see:
- Fish Intake Associated With Brain Shrinkage
- Bacon, Eggs, and Gestational Diabetes During Pregnancy
- Mercury vs. Omega-3s for Brain Development
- How Long to Detox From Fish Before Pregnancy
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