Apple Peels Put to the Test for Chronic Joint Pain

Apple Peels Put to the Test for Chronic Joint Pain
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Are the health benefits associated with apple consumption just due to other healthy behaviors among apple eaters?

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Below is an approximation of this video’s audio content. To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video.

Regular apple intake is associated with all sorts of good things, like living longer—particularly a lower risk of dying from cancer. Here’s the survival curve of elderly women who don’t eat an apple a day. Ten years out, nearly a quarter had died, and 15 years out, nearly half were gone. But, those who average like a half an apple a day don’t drop off as fast, and those eating an apple a day—more than three and a half ounces of apples a day—like a cup of apple slices—stayed around even longer. Yeah, but maybe people who eat apples every day just happen to practice other healthy behaviors, like exercising more, or not smoking, and that’s really why they’re living longer. Well, they controlled for most of that—obesity, smoking status, poverty, diseases, exercise—so as to compare apples to apples (so to speak!).

But, what they didn’t control for was an otherwise healthier diet. Studies show that those who regularly eat apples have higher intakes of not just nutrients like fiber, found in the apples, but they’re eating less added sugar, less saturated fat—in other words, they’re eating overall healthier diets. So, no wonder apple eaters live longer, but is apple eating just a marker for healthy eating, or is there something about the apples themselves that’s beneficial? You don’t know, until you put it to the test.

There are all sorts of fun studies like this, where subjects were randomly assigned in the morning to nothing, a caffeinated energy drink, black coffee, or an apple—given that athletes use a variety of common strategies to stimulate arousal, cognition, and performance before their morning training. Did the apple hold its weight? Yes, appearing to work just as well as the caffeinated beverages. The problem with these kinds of studies, though, is that they’re not blinded. Those in the apple group knew they were eating an apple. So, there may have been an expectation bias, placebo effect, that made them unconsciously give that extra bit of effort in the testing, and skew the results. You just can’t stuff a whole apple into a pill.

That’s why researchers, instead, test specific extracted apple components. So, they can perform a double-blind, placebo-controlled study, where half get the fruit elements, half get a sugar pill, and you don’t know until the end who got which. The problem there, though, is that you’re no longer dealing with a whole food—removing the symphony of interactions between the thousands of phytonutrients in the whole apple.

Most of those special nutrients are concentrated in the peel, though. Instead of just dumping millions of pounds of nutrition in the trash, why couldn’t researchers just dry and powder the peels into opaque capsules to disguise them, and then run blinded studies with that? Even just “[a] small amount could greatly increase…phytochemical content and antioxidant activity…”

The meat industry got the memo: “Dried apple peel powder decreases microbial expansion in [meat] and protects against carcinogen production…” when you cook it. And, “[o]ne of the carcinogens formed during [the] grilling of meat is [a] beta-carboline” alkaloid, a neurotoxin, which may be contributing to the development of neurological diseases, like Parkinson’s. I did a video about that a while ago. Uncooked meat doesn’t have any; the neurotoxin is formed when you cook it. But, you can cut the levels in half by first marinating the meat with dried apple peel powder.

And, it also cuts down on the amount of fecal contamination bacteria in the meat. Fecal bacteria growing before and after the addition of dried apple peel powder, in pork, beef, and turkey. Apple peels can also inhibit the formation of genotoxic, DNA-damaging, heterocyclic amines, cutting the levels of these cooked meat carcinogens by up to more than half. “In view of the risks associated with consuming [these cancer-causing compounds in meat], there is a need to reduce exposure by blocking HCA formation such as by adding [apple peel powder] during the cooking of meats to [help] prevent their production.” I can’t think of any other way to reduce exposure.

What about consuming apple peels directly? Dried apple peel powder was found to exhibit “powerful anti-inflammatory and antioxidant action.” But, this was in mice. Does it have anti-inflammatory properties in people? You don’t know, until you put it to the test.

A dozen folks “with moderate loss of joint [range of motion] and associated chronic pain” were given a spoonful of dried apple peels a day for 12 weeks, and pain scores dropped month after month, and the range of motion improved in their neck, shoulders, back, and hips. Conclusion: “Consumption of dried apple peel powder was associated with improved joint function and…pain reduction.” Why just “associated”? Because there was no control group; so, they might have all been just getting better on their own, or it could have been a placebo effect. But hey, why not give apple peels a try by eating more apples?

Please consider volunteering to help out on the site.

Image credit: jackmac34 via Pixabay. Image has been modified.

Motion graphics by Avocado Video.

Below is an approximation of this video’s audio content. To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video.

Regular apple intake is associated with all sorts of good things, like living longer—particularly a lower risk of dying from cancer. Here’s the survival curve of elderly women who don’t eat an apple a day. Ten years out, nearly a quarter had died, and 15 years out, nearly half were gone. But, those who average like a half an apple a day don’t drop off as fast, and those eating an apple a day—more than three and a half ounces of apples a day—like a cup of apple slices—stayed around even longer. Yeah, but maybe people who eat apples every day just happen to practice other healthy behaviors, like exercising more, or not smoking, and that’s really why they’re living longer. Well, they controlled for most of that—obesity, smoking status, poverty, diseases, exercise—so as to compare apples to apples (so to speak!).

But, what they didn’t control for was an otherwise healthier diet. Studies show that those who regularly eat apples have higher intakes of not just nutrients like fiber, found in the apples, but they’re eating less added sugar, less saturated fat—in other words, they’re eating overall healthier diets. So, no wonder apple eaters live longer, but is apple eating just a marker for healthy eating, or is there something about the apples themselves that’s beneficial? You don’t know, until you put it to the test.

There are all sorts of fun studies like this, where subjects were randomly assigned in the morning to nothing, a caffeinated energy drink, black coffee, or an apple—given that athletes use a variety of common strategies to stimulate arousal, cognition, and performance before their morning training. Did the apple hold its weight? Yes, appearing to work just as well as the caffeinated beverages. The problem with these kinds of studies, though, is that they’re not blinded. Those in the apple group knew they were eating an apple. So, there may have been an expectation bias, placebo effect, that made them unconsciously give that extra bit of effort in the testing, and skew the results. You just can’t stuff a whole apple into a pill.

That’s why researchers, instead, test specific extracted apple components. So, they can perform a double-blind, placebo-controlled study, where half get the fruit elements, half get a sugar pill, and you don’t know until the end who got which. The problem there, though, is that you’re no longer dealing with a whole food—removing the symphony of interactions between the thousands of phytonutrients in the whole apple.

Most of those special nutrients are concentrated in the peel, though. Instead of just dumping millions of pounds of nutrition in the trash, why couldn’t researchers just dry and powder the peels into opaque capsules to disguise them, and then run blinded studies with that? Even just “[a] small amount could greatly increase…phytochemical content and antioxidant activity…”

The meat industry got the memo: “Dried apple peel powder decreases microbial expansion in [meat] and protects against carcinogen production…” when you cook it. And, “[o]ne of the carcinogens formed during [the] grilling of meat is [a] beta-carboline” alkaloid, a neurotoxin, which may be contributing to the development of neurological diseases, like Parkinson’s. I did a video about that a while ago. Uncooked meat doesn’t have any; the neurotoxin is formed when you cook it. But, you can cut the levels in half by first marinating the meat with dried apple peel powder.

And, it also cuts down on the amount of fecal contamination bacteria in the meat. Fecal bacteria growing before and after the addition of dried apple peel powder, in pork, beef, and turkey. Apple peels can also inhibit the formation of genotoxic, DNA-damaging, heterocyclic amines, cutting the levels of these cooked meat carcinogens by up to more than half. “In view of the risks associated with consuming [these cancer-causing compounds in meat], there is a need to reduce exposure by blocking HCA formation such as by adding [apple peel powder] during the cooking of meats to [help] prevent their production.” I can’t think of any other way to reduce exposure.

What about consuming apple peels directly? Dried apple peel powder was found to exhibit “powerful anti-inflammatory and antioxidant action.” But, this was in mice. Does it have anti-inflammatory properties in people? You don’t know, until you put it to the test.

A dozen folks “with moderate loss of joint [range of motion] and associated chronic pain” were given a spoonful of dried apple peels a day for 12 weeks, and pain scores dropped month after month, and the range of motion improved in their neck, shoulders, back, and hips. Conclusion: “Consumption of dried apple peel powder was associated with improved joint function and…pain reduction.” Why just “associated”? Because there was no control group; so, they might have all been just getting better on their own, or it could have been a placebo effect. But hey, why not give apple peels a try by eating more apples?

Please consider volunteering to help out on the site.

Image credit: jackmac34 via Pixabay. Image has been modified.

Motion graphics by Avocado Video.

Doctor's Note

Here’s that meat carcinogen video I alluded to in the video: Essential Tremor & Diet. The HCAs I talked about are heterocyclic amines. More on those in Reducing Cancer Risk in Meat-Eaters.

Bunch more apple videos eventually coming up, but in the meanwhile you can bite into these:

For more on natural joint remedies, see:

If you haven’t yet, you can subscribe to my videos for free by clicking here.

88 responses to “Apple Peels Put to the Test for Chronic Joint Pain

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    1. My husband had a hip replaced in 2003. Many years later a urologist put him on Cipro and he found it caused the replaced hip to hurt. Off that nasty drug, which is extremely dangerous, the pain went away. There are several other drugs that are similar and cause the same problems, including Levaquin and Avelox.

      Down the road a few years he needed the other hip replaced. By then we had learned about prolotherapy. He had that instead, it cured the problem, and he was able to avoid the second hip replacement.




      5
      1. Rebecca, I’m curious about the use of prolotherapy to avoid hip replacement. It seems that it would treat only the symptoms and not really do anything for the underlying cause of the disease (cartilage loss and bone to bone contact, see below) Wouldn’t a hip replacement be needed eventually, if the joint were continued to be used? Is this being pursued as a temporary measure? Just wondering. I don’t have this problem yet, but maybe someday I will be faced with this issue.

        Osteoarthritis is the most common type of arthritis and is seen especially among older people. Sometimes it is called degenerative joint disease. Osteoarthritis mostly affects cartilage, the hard but slippery tissue that covers the ends of bones where they meet to form a joint. Healthy cartilage allows bones to glide over one another. It also absorbs energy from the shock of physical movement. In osteoarthritis, the surface layer of cartilage breaks and wears away. This allows bones under the cartilage to rub together, causing pain, swelling, and loss of motion of the joint. Over time, the joint may lose its normal shape. Also, small deposits of bone—called osteophytes or bone spurs—may grow on the edges of the joint. Bits of bone or cartilage can break off and float inside the joint space. This causes more pain and damage.




        5
        1. WFPB-Hal,

          You might want to take a look at the following recent article by Dr. Mirkin, a well known sports medicine authority:

          http://www.drmirkin.com/joints/osteoarthritis-has-doubled-in-the-last-fifty-years.html

          According to the article, “It now appears that osteoarthritis may be a disease of inflammation caused mostly by lack of exercise, being overweight, eating a pro-inflammatory diet and having inadequate vitamin D levels (JAMA, November 22, 2017).” The mention of “lack of exercise” relates also to bone health, as several people have pointed out elsewhere. But the deleterious consequences of lack of sufficiently challenging exercise are far broader than that, including virtually every lifestyle-related disease, including e.g. age-related problems of sarcopenia (muscle loss), loss of mitochondria (energy producing organelles) and aerobic capacity,. For those who are interested in pursuing the topic of exercise, Dr. Mirkin is a reliable source of up-to-date information.




          7
          1. gengogakusha, Thanks for your informative reply. I do get plenty of aerobic exercise plus some moderate weightlifting. Also, I’m WPF (& no SOS) now, so I hope I never have joint problems that need any kind of treatment!




            3
        2. WFPB-Hal,

          I first learned about prolotherapy from a woman who had been an airline pilot flying 747s on the Seattle-Asia route. She had cured two herniated discs in her back with prolo.

          She explained it by saying that the doctor injects a solution of a sugar-water solution around the joint being treated. This sets up inflammation and causes the tendons or ligaments (I forget which) to grow stronger, pulling the affected joint apart so it no longer impinges painfully. She claimed the treatment was permanent and curative. I don’t suppose it cures the actual joint surfaces, but keeps the joint from this source of pain by keeping the parts a bit apart.

          My husband lived with terrible pain in his right hip for many years because at the time the only replacement offered involved a 10″ incision through muscles and required months of recovery.

          When he learned of a doctor in Portland, OR, who was the only one doing minimally invasive hip replacements anywhere in the Pacific Northwest, we went there for his surgery. He’s been happy with it, though like any artificial thing in your body, there are a few problems now and then.
          Still, he was very quickly walking the golf course for the first time in years, and three months after surgery he tiled our 40′ hall and entry hall, which astounded me.

          He dreaded having another replacement, even though his results were quite good. So, when he talked with the doctor about prolotherapy, he was convinced to try it. The recovery from prolo was painful, since he wasn’t allowed to take anti-inflammatory meds. It sets up an inflammatory process on the way to do its’ healing work. Still, this was far more minimally invasive than the hip replacement had been, and the recovery was even faster.

          He had the prolo about 8-10 years ago and so far he hasn’t had any more trouble with that hip, while the replaced one is now starting to slough off metal and is due for another replacement. I don’t know if prolo would work in that situation or not.

          One problem with prolo is finding a doctor who is experienced in it, but there should be resources online.




          5
          1. livewire, Thanks for your informative reply. I’m WPF (& no SOS) now, so I hope I never have joint problems that need any kind of treatment!




            0
      2. Rebecca, I am interested, too.

        I have friends who have obesity issues and they can’t have things like knee replacements and I have known elderly people who had their knees replaced, but they ended up with infections, which were so hard to get rid of that the doctors were talking about removing the knee replacement and fusing the leg into a peg leg type of thing. My friend has a coworker who has had that happen and that person says, the peg leg is so useless that he wants his lower leg amputated.

        I have looked at Micropulse ICES and Curatron, because PEMF can regrow cartilage about 30% of the time, within two years, but two years is a long time to try it, without knowing if it will work. My knees are still okay, but I never want these surgeries. Ever.




        4
          1. Deb, There is so much more to obesity than eating sugar. In fact, it is difficult for the body to turn natural sugar from foods into fat. But researchers can examine fat from human bodies and determine which fatty foods they have been eating, because when bodies store it, it maintains identifiable characteristics. As Dr McDougall says, “The fat you eat is the fat you wear.”

            A good place to begin learning is on Dr McDougall’s site or Youtube. Look for a talk called The Pleasure Trap and another called The Cram Circuit, both by Doug Lisle. They will give you the background to better understand why so many people are obese or overweight today.




            4
      1. I thought I needed a hip replacement but stretching completely eliminated the problem. I do the 6 stretches in a book (found in the library) called “3 minutes to a pain-free life” written by physical therapist Joseph Weisberg. Check out book reviews. I could barely walk and sleeping on my side was too painful. I am not saying it will work for everyone. When I started the stretches I couldn’t bend one knee more than 90 degrees. I just did the best I could. Now I can do the stretches easily. I walk as far as I want and sleep on my side with no pain. It has been 10 years since I started stretching. If I don’t do my stretches for a couple of weeks the pain starts to return. The stretches are similar to the yoga poses: child pose; cat & cow; touching your toes with legs apart; cobra; squatting; sitting cross legged with fingers laced, palms to ceiling, arms straight overhead. I also find the pigeon yoga pose stretches the hip area. It can be done on the floor or in a chair. They seem to simple to be effective, but they are very effective.




        2
    2. Hello Ron. Thanks for your comments!

      Dr. Greger has a whole section related to join health and treating joint symptoms, you can watch them here, at NF.org

      All Videos for Joint Health

      I’m sure you’ll find very useful information!




      0
  1. You can’t go wrong eating a whole food plant based diet.. Too much science to back it up… and AND AND. It can’t hurt you like drugs..
    mitch




    10
  2. Whenever Dr. G says “you don’t know, until” I start grinning, because I know what’s coming … “you put it to the test!” Definitely one of his trademarks.




    12
  3. What a laugh! I love when Dr. Greger finishes with the obvious! If only people could get the understanding that it is the whole food, not its manipulated form that is the real gold when it comes to nutrition.

    I leave for work with an apple in my purse. Yay for food as medicine!

    A healthy and proud monthly supporter of Nutritionfacts. org




    12
  4. Apple peel has an additional pain reducing benefit. The ursolic acid in apple peel
    and Tomatidine in green un ripe conventional tomatoes and ripe organic tomatoes
    reverse age related muscle atrophy. (U of Iowa). My experience is that both
    Tomatidine and Ursolic Acid help me to quickly regrow leg muscles which reduced
    the pain in my severely arthritic knees by 98%.




    6
    1. Sydney were these sourced entirely from food or supplements? If from food how much did you consume to get those amazing results? Since apples are high in fodmap I wonder if they would need to be excluded for me although maybe the peel is different?




      1
      1. Lida

        What means fodmap?

        The U of Iowa report said the tomatidine is highest in green unripened tomatoes. So I started out getting a case of green tomatoes from local supermkt. But it became a pain to cook them all and put them in containers in freezer.

        The report also said the tomatidine deteriorates as the tomatoes ripen, but that there was still some in ripe organic tomatoes. So I experimented and found ripe (but not over ripe) organic tomatoes work just as well and are easier to procure.

        It’s a little confusing at first trying to judge how much to take, but since in my case, the tomatidine seems to effect my Ciliary muscles (around the eye lens) I try to take another tomato (or juice) before my eyesight starts to deteriorate.

        I have noticed that on days when I ate an apple, It was much easier getting to the bathroom in time, even when the urge to urinate is very strong.

        My experience is that it important for any elderly person (over 50? – certainly over 60) to eat both an apple a day and enough tomatoes to keep their muscles strong. (Exercise plenty too)

        WARNING – I have found sometimes I get COLD after eating the tomatoes. My intuition is that when the muscles get stronger it increases the iron dependent myoglobin inside the muscles and sucks iron out of the blood.

        ANTIDOTE: Simply eat (chew thoroughly) a slice of 100% whole rye bread. Mestenmacher rye contains 15% of the daily DV for iron per slice. By the time I’ve eaten a whole slice I feel warmer. I always carry a couple of slices when I go out.

        The doctors who did the report said they anticipate putting the tomatidine and ursolic acid in pills.

        Since apples and tomatoes are very good foods with cancer fighting capabilities etc, I expect to continue eating the apples and tomatoes even after the pills come out – probably a few years.




        2
      1. CD

        I’ve noticed that Ursolic Acid is found in many foods. The reason it is specified in the U of Iowa report might be because it might be present in higher concentrations in apple skin than other foods.

        I have found that eating both two or three organic tomatoes/day plus an organic Granny Smith apple each day has helped both skeletal muscles and also urethral and Celiary muscles. I think they also strengthen the muscle layer inside leg veins, but that is slower.

        To be clear, one has to keep taking both in appropriate quantities.




        1
  5. Gosh, and there are still smart people publishing recipes that mention applesauce instead of apple puree. For example, here’s an (almost) whole food plant-based coffee cafe recipe. I’ve made this one with apple puree. The ground apple peals are undetectable by taste or texture.




    4
    1. I’ve cooked whole cored apples, cut in quarters and with the peels left on, in a small amount of water in my Instant Pot (electric pressure cooker), then blenderized the cooked apples (with an immersion blender) in the pot to make applesauce. That’s it: just cooked apples, Simple, easy, fast, and very tasty! Plus, I’m way to lazy to peel apples, and I prefer to eat the peels myself and not feed them to the earthworms in my compost bin.




      0
  6. Just wait, the supplement industry will be selling DAPP capsules soon enough (if not already) and we won’t have to deal with those tasty little pre-packaged, all natural, sweet and complete fruits.

    No just give us the powder, charge us ten times more for fancy package and pleasant words and images…

    –oh wait THIS IS the supplement industry–so maybe not really DAPP at all, but cornstarch and sawdust with artificial apple aromas will be close enough.

    (i eat a bag of apples two or three times each month.)




    9
    1. Wade

      You can already buy apple fibre (made from apple pomace) – 12 oz for about US $5 if you are interested – which mostly peel I think.




      2
      1. Sure, thanks but you likely missed the part about “I eat bags of apples each month”. I’m in no way interested in processed food much beyond pre-ground flax-seeds and pre-milled wheat/masa and a few condiments and spices. I garden, cook, and wild harvest. Cheers and pectin yo!




        0
        1. Wade,

          Too bad we aren’t neighbors. We were out looking yesterday to see if the nettles are up. Yes, they are, by the way, but not enough to harvest, where we were looking.




          0
  7. https://youtu.be/dmd7-KjE62o In this link Mel Gipson tells how Dr. Neil Riordan at his Clinic in Panama was able to vastly improve the health of his 92 year old father with stem cells. However, Tom Goff says that Dr. Neil Riordan is a fraud. But, Mel Gipson disagrees and says that Dr. Neil Riordan’s stem cell therapy is not a fraud but has greatly improved his father’s health. Who do you believe? Tom Goff or Mel Gipson? Here’s the link: https://youtu.be/dmd7-KjE62o




    1
    1. John

      There certainly are many fraudulent doctors.

      I tried listening to the link and got turned off by the rambling non-specifity.




      0
    2. Bill

      I have never witten or claimed that Riordan is a fraud. That statement of yours simply isn’t correct. I have described him as a “health entrepenerur” – but that just repeating the description of him in the newspaper article I linked previously.

      Another thing you got wrong is the bloke’s name. It’s Mel Gibson.

      On that particular point of a celebrity endorsement, let me quote you Dr Mirkin

      “• The stem cells that you receive in most of these clinics usually have none of the therapeutic advantages that research labs use to make their stem cells more effective. For example, research labs are making stem cells better by manipulating and transplanting DNA genetic material.
      • No government agency is checking these unapproved and unregulated stem cell clinics for effectiveness or safety.
      • The procedures that are used in most of the clinics have not been approved for the general population.
      • Celebrity endorsements and patient testimonials are meaningless.
      • The prices charged are often outrageous.
      • Health insurance plans seldom cover stem cell treatments done at these clinics. ”
      http://www.drmirkin.com/weekly-ezine-page/be-wary-of-stem-cell-clinics.html

      Wht are you promoting Dr Riordan and his expensive clinic by the way? You aren’t the artist formerly known as Jerry Lewis are you?




      2
    3. There’s also the case of Gordie Howe, 86 year old Hockey legend who had a series of strokes that led to him being unable to walk or remember the names of his kids, who had stem cell therapy back in 2014 and a few hours after having the treatment got up and walked to the bathroom. It’s a short read in the article linked below.

      I also read a few days ago, in Fortune magazine online, I think, that the writer was bashing the govt. budget for allowing over 100 million dollars for alternative medicine treatments. I have no idea if he is paid under the table by big Pharma, but that is my suspicion.

      Big things are happening. We no longer live in a linear world. These are exponential times. The first step to living longer and healthier is acceptance that you can.

      And yes, that includes accepting that while WFPB diet is good, it is not the endgame.

      https://www.yahoo.com/news/know-gordie-howe-controversial-stem-163857544.html




      0
      1. John Brodie, former SF 49ers QB also had stem cell treatment some years ago, as I recall. Willie Nelson another beneficiary of stem cell treatment for COPD. Worked so well he is now back able to smoke pot. ‘-)




        0
          1. Good finds for balance Tom.

            But if I may offer still more counter balance, in the Willie Nelson case he has enjoyed another year of breathing that he wouldn’t have had if not for the treatment.

            And we don’t know how he lived during that year.

            I knew a guy that had a lung transplant after smoking almost all his life. After the transplant he started back smoking again thinking he had new lungs and could smoke for years without penalty. He died.

            And the guy with the growth in his spine. Sounds like he had other peoples stem cells with who knows what genetic make up used in his treatment.

            My own experience with being transfused with young people’s plasma means no actual cells were transfused… only proteins of a younger nature than my own. (Still no buyer’s remorse for paying for and undergoing that treatment.)

            I’m thinking the John Brodie ball player and Gordie Howe hockey player went to the clinic in the U.S. and had their treatments made from their own cells into IPSCs (Induced Pluripotent Stem Cells.) I could have that confused with other stuff I’ve read but I think that is the procedure. I’m almost positive that is the case in the Willie Nelson treatment.

            So, while famous people can be used to encourage the use of stem cell treatments, they can also be used to discourage treatment. What would be really helpful would be knowing how average people have fared, as there have been thousands upon thousands of people who have done these treatments.

            If there was widespread failure of these treatments, I would think that would have been in the news as there are many in the media who do not want to believe in anything over and above the standard life span.

            Or maybe this is the media doing its due diligence and there just isn’t enough collected data to present to the public yet. I’m thinking however, that it may be like a Dr. who railed against taking supplements as they only created expensive urine.

            A few years later he apologized for that over and over in his commercials recommending certain brands of vitamins. ‘-)




            0
            1. Follow up that I forgot to mention:

              I’m thinking a lot of treatment other than stem cells may be where the road to prevention leads. It may very well turn out that stem cell treatments become the standard (but I really think in time the CRSPR Cas9 + other Cas enzymes will be where treatment excels, by snipping out the bad code in our genes and inserting the good or better sequence in their place.)

              I really wouldn’t count on my GP doctor to stay on top of these new developments. Things happen too fast and there’s just too much to take in by anything other than a specialist. And specialists are usually called in when things are already bad.

              It behooves us to stay on top of new research on our own.




              0
  8. Where the apples are non-organic (i.e., are sprayed with pesticides), is the net effect of apple peels on health still positive for individuals with joint problems? How about for people without joint problems?




    2
    1. ehanson

      My response is:

      Spend the money and get organic.
      There are many good things in apples and all of them are present in greater quantities in organic apples.




      3
    2. ehansen, Dr. Greger explains elsewhere that organic is better but you still get the benefits from conventional produce so it trumps not eating it at all. So he recommends if you can’t get organic, to keep eating lots of fruits and veggies. I do agree with Sydney though, get organic if at all possible.




      4
  9. I have a question. Almost a year ago to the date I suffered a massive heart attack. Since then I have taken more medication than in all my years of previous Life. Somehow my cholesterol is off the charts and no matter how hard I try, cannot get it to “normal” levels. Used to take statins and nearly died from them. I am allergic. Have switched diet to a much more careful intake of veggies, fruits, healthy stuff, near zero fried foods and much less amounts but still triglycerides and LDL stay off the charts. Any sane solutions???




    0
    1. gd, I’m sorry to hear of your heart attack and ongoing problems. If I were in your shoes I would call TrueNorth Health Center ( http://www.healthpromoting.com/clinic-services) and talk (free) with Dr Alan Goldhamer to see if he felt a stay there would help your problem. They have a 32+-year, very safe track record of helping people with seemingly intractable health problems through either water-only fasting or whole foods plant based diet with no sugar, oil, salt, or flour. It would certainly be a good idea to at least talk with him.

      In the meantime, you should cut out ALL added fat from your diet. If you must have fried foods, get an air fryer to save yourself from eating highly processed oils.




      5
    2. gd, you’ll find lots of great advice about that here. I have some anecdotal evidence for you… A relative of mine who eats a Standard American Diet had very high cholesterol but had started eating raw sunflower seeds everyday and was surprised to find out his cholesterol had lowered significantly. Could have been due to replacing unhealthy snacks with a whole plant food or the seeds themselves but my guess would be both. Anyways, Dr. Greger has quite a few great videos here on cholesterol which I highly suggest checking out. Also, I highly recommend Dr. Greger’s book “How Not To Die.”

      I assume the advice of cutting out all “added” fat by another commenter was meant to mean added oils and not avoid seeds and nuts which are shown to be beneficial to the heart.

      Have you gone completely plant based? Unlike animal products, such as eggs, plants do not contain cholesterol. Our bodies are not meant to ingest additional cholesterol, we produce it on our own. Also stop consuming coconut oil and palm oil if you’re currently doing so. If say your plant milk of choice is coconut milk, opt for soy milk or a nut or seed milk or oat milk, etc. Dr. Greger has videos regarding coconut oil and even coconut milk as well.

      Good luck!!




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      1. Also, drastically lower your salt intake or omit additional salt entirely. I’m not sure if salt is connected with high cholesterol but it is very bad for arterial function. Some people here do not use salt at all but I would not enjoy that, however since learning about it thanks to Dr. Greger, I’ve been able to lower my salt tolerance drastically because our taste buds change all the time. It used to be the case where I would prepare something and others would notice that it was a little too salty or even very overly salted whereas it wouldn’t seem so to me, now I’ll prepare something and others barely taste any salt but it tastes salty to me. Buying pre made products with no salt added helps a lot in lowering intake, for example I used to use salted peanut butter now I just won’t even eat that. And interestingly, the unsalted used to taste bland to me and now it’s amazing. And speaking of things like peanut butter, make sure you read ingredients! Stay away form things with added oils especially hydrogenated oils! Hydrogenated vegetable oil is laden with transfat, they actually alter the vegetable oil to mimic animal fat and it’s the only time a plant “food” actually contains transfats.




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    3. You could try

      1. consuming amla every day
      https://nutritionfacts.org/video/amla-vs-drugs-for-cholesterol-inflammation-and-blood-thinning/

      2. getting an hour or two of exercise very day
      https://www.webmd.com/cholesterol-management/features/exercise-to-lower-cholesterol

      3. if you drink coffee, drink only filter coffee
      https://www.sciencedaily.com/releases/2007/06/070614162223.htm

      4. eating tradtional porridge (ie made from oats preferably oat groats. steel cut oats or whole rolled oats) every day. Cook it in water not milk to reduce your saturated fat intake (saturated fat raises cholesterol)
      https://www.sciencedaily.com/releases/2016/10/161007085247.htm

      5. eat beans every day
      http://www.fasebj.org/doi/abs/10.1096/fasebj.31.1_supplement.966.13




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      1. Oh, some more anecdotal stuff! TG’s bean recommendation made me remember that my cousin who does not eat right at all and despite being in her 20’s was told she needed to lower her cholesterol, she didn’t change her diet but did start eating just a small amount of beans everyday… I think she said a half of a cup about, and her cholesterol had significantly lowered by her next doctor appointment, she attributed it to the beans but was not eating them for that reason, she just started liking them she told me. But enough stories about my relatives. Lots of great science out there on the amazing benefits plant foods have on cholesterol, but I do find these stories pretty interesting and love hearing them from people so I figured I would share if it could offer some inspiration.




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    4. Hi I’m a RN health support volunteer with nutritionfacts.org. I’m sorry to hear about all that. It must be very frustrating to be working so hard and not getting the results you would like. First of all, congratulations on all you are doing. It is worth it.

      Are you eating completely whole food plant based? Avoiding ALL oil, including “healthy oils” like olive oil? Avoiding added sugar? We recommend eating everything on Dr. Greger’s Daily Dozen. I would start with that. It is available in a free app:
      https://nutritionfacts.org/video/dr-gregers-daily-dozen-checklist-2/
      https://nutritionfacts.org/video/how-not-to-die-from-heart-disease/

      If you are already eating everything on Dr. Greger’s daily dozen and not eating any added oils or sugars and still having suboptimal cholesterol levels, then you need to add foods that are specifically known to lower cholesterol levels. Dr. Greger has some information in this blog:
      https://nutritionfacts.org/questions/what-can-i-do-to-lower-my-cholesterol-it-seems-ive-tried-everything/

      You might also like some of Dr. Esselstyn’s work. He’s another fighter in the plant based nutrition battle. His program was specifically designed for patients with severe heart disease. Many had failed bypass surgeries. His plant based program is a little stricter for that reason. His patients had phenomenal results in reducing their cholesterol and reversing their heart disease. He has a great in depth talk on youtube:
      https://www.youtube.com/watch?v=AYTf0z_zVs0
      http://www.dresselstyn.com/site/

      Also, you may need to give it more time. If you had an unhealthy diet for years, it may take more time. Don’t give up on the healthy lifestyle.

      All the best to you. Hang in there!
      NurseKelly




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  10. For me the issue with diet extrapolation is dosing. How many appples or green tomatoes are required in humans to slave off muscle degeneration?

    By: Jennifer Brown | 2015.09.07 | 06:44 pm

    As we grow older, we lose strength and muscle mass. However, the cause of age-related muscle weakness and atrophy has remained a mystery.

    Scientists at the University of Iowa have discovered the first example of a protein that causes muscle weakness and loss during aging. The protein, ATF4, is a transcription factor that alters gene expression in skeletal muscle, causing reduction of muscle protein synthesis, strength, and mass. The UI study also identifies two natural compounds, one found in apples and one found in green tomatoes, which reduce ATF4 activity in aged skeletal muscle. The findings, which were published online Sept. 3 in the Journal of Biological Chemistry, could lead to new therapies for age-related muscle weakness and atrophy.

    “Many of us know from our own experiences that muscle weakness and atrophy are big problems as we become older,” says Christopher Adams, M.D., Ph.D., professor of internal medicine in the UI Carver College of Medicine, and senior study author. “These problems have a major impact on our quality of life and health.”

    Previously, Adams and his team had identified ursolic acid, which is found in apple peel, and tomatidine, which comes from green tomatoes, as small molecules that can prevent acute muscle wasting caused by starvation and inactivity. Those studies set the stage for testing whether ursolic acid and tomatidine might be effective in blocking the largest cause of muscle weakness and atrophy: aging.

    In their latest study, Adams’ team found that ursolic acid and tomatidine dramatically reduce age-related muscle weakness and atrophy in mice. Elderly mice with age-related muscle weakness and atrophy were fed diets lacking or containing either 0.27 percent ursolic acid, or 0.05 percent tomatidine for two months. The scientists found that both compounds increased muscle mass by 10 percent, and more importantly, increased muscle quality, or strength, by 30 percent. The sizes of these effects suggest that the compounds largely restored muscle mass and strength to young adult levels.” https://now.uiowa.edu/2015/09/keeping-older-muscles-strong
    It appears that Fiji apples are most effective offering 50 mg ursolic acid /apple.
    https://www.researchgate.net/publication/223392746_Isolation_of_ursolic_acid_from_apple_peels_by_high_speed_counter-current_chromatography
    I believe the equivalent of 9 medium apples/day have been used in studies on muscle building and protection however many can benefit from 3 Fijis /day.




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  11. I have had my gallbladder removed, plus most recently 2015, major surgery for ovarian cancer. Now afterwards, as of 2017 to present, i have sever stomach pain when I eat apple peels, almonds and skin of eggplant. I love to eat the apple alone, but I want to know how to stop the pain, but reap the benefits of the apple peel. I have osteophytes in my neck, shoulder pain, herniated lower disc in back. Finger joint pain, stiffness at only 44yrs old. Im vegatarian, therefore in trying all I can to stop pain.




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    1. Maybe you could grind the apples with the skins in a blender or food processor. It wouldn’t be the same as crunching into a crisp apple, but perhaps you could eat the skin that way without problems.




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    2. are you entirely plant based (no animal products ever)? I would definitely go completely WFPB. Sounds like a digestive issue with the skins, you could try blending them up in smoothies or even dehydrating them and grinding them up perhaps. I doubt you’d have any issues if you blended them in a high speed blender, hopefully it can’t hurt too badly to try if you haven’t already.

      Good luck!!




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    1. Dr. Greger explains that the benefits of even conventional produce outweighs the negatives however he does say organic is better, obviously… The U.S and other governments should be subsidizing organic produce. Anyways though, I don’t think apples are considered “toxic” anywhere, I believe they’re just one of the foods on the “most important foods to get organic” list, to ROUGHLY paraphrase whatever title that is… maybe it’s the dirty dozen or something like that… I don’t know.




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  12. Have had great interest in all Dr G videos, and this latest about green apple peel is no less intriguing than the usual vids. However, doing a net search for Green Apple Extract Powder finds that almost all of the stuff available is from China or South Korea, which makes me hesitant to take this product as an ‘unpolluted’ product or at least not up to USDA standards of byproducts or contaminates. Anyone familiar with a US made product or at least good result or proven quality of any Asian brand?




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    1. Sorry, no.

      However, you could look at apple fibre instead. That’s much cheaper and pretty much the same thing. I understand that most aple fibre powders in the US are US-sourced but you’d have to confirm that with the manufacturer.for each specific product. I know that NOW food sell an apple fibre powder if you wanted to check it out.




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  13. If eating conventional apples, I have read soaking them in baking soda and water for 15 minutes removes much of the pesticide. I think the ratio was 1 tsp per 2 cups of water. I have also read, cut out the stem area of an apple as pesticides accumulate in that dimple by the stem.




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    1. Dr. Greger actually has a video on here about the best ways to wash off pesticides and it turns out that salt water is the best, but I’d look for the video to check ratios and such.




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  14. Hi

    I searched your site for any information on the use of Glucosamine HCL with MSM. My Dr recommended I take these food supplements due to lower back wear and tear (mild arithitus). I wondered if there is any evidence for these and risks?




    1
    1. Hi I’m a RN health support volunteer with NutritionFacts. In general, Dr. Greger recommends avoiding all supplements with a few exceptions given that they are poorly regulated and not been shown to help much:
      https://nutritionfacts.org/topics/supplements/
      https://nutritionfacts.org/video/dangers-of-dietary-supplement-deregulation/

      A lot of the promoted benefit of this supplement is attributed to the sulfur, which you can get plenty of on a healthy plant based diet. These are naturally occurring supplements that the supplement industry had tried to pull out of nature and stuff in a pill.

      I’d first make sure you are eating a healthy diet, like everything on Dr. Greger’s daily dozen;
      https://nutritionfacts.org/video/dr-gregers-daily-dozen-checklist-2/

      And then I’d check out some of the information Dr. Greger has on back pain and arthritis. Here are just a few:
      https://nutritionfacts.org/video/cholesterol-and-lower-back-pain/
      https://nutritionfacts.org/video/back-in-circulation-sciatica-and-cholesterol/
      https://nutritionfacts.org/topics/arthritis/

      All the best to you,
      NurseKelly




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  15. I love all your videos encouraging a plant based diet and showing all the benefits of eating these foods. I suffer from a variety of health issues (Hypothyroid, Raynauds, Complex aura migraines, & Food allergies to name a few) and desire to eat a plant based diet, but the biggest stuggle I have is finding a healthy balanced diet that doesn’t aggravate my Gastroparesis. Could you please do a video on how to eat a balanced plant based diet when you have Gastroparesis, and how to cure/improve the condition?




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  16. HERBAL FORMULA

    I am a 50 years old female diagnosed with Rheumatoid Arthritis 2 years ago but have had symptoms for at least 20 years. I was taking methotrexate and Cymbalta, as well as infusions of Remicade, nothing worked for me. All my pain was from my waist down and certainly not something I can stand. The only treatment that has been successful has been the taking of RA herbal remedy i purchased from Best Health herbal centre. I now wake up every morning without pain. I have been pain-free period for more than 4 months. I have regular blood tests and do not experience any of the side effects from taking the herbal remedy. Thank God this works for me. I feel great!.




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  17. According to the study featured at 1:20, dietary fibre intake is exactly the same between Whole Apple Consumers and Whole Apple Non-Consumers. Yet Dr. Greger states that fibre intake is higher among apple consumers. Source?




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  18. Hello, i am reaching out to you guys for help. I have reached my breaking point with my doctors or should i say all doctors in Delaware. Ever since i first started my period it never stopped. it would be so heavy in the past it would go through my clothes it would stain pants i would have to change pants several times during the day when i would get up in class there would be a huge stain on the seat. i went to the E.R years ago i don’t remember the exact date i was admitted for a week and they told me they ran every test possible everything came back normal and i was told well at least I’m not dying and that was the end of that. i was told to get a hysterectomy at the age of 16 but i told them i did not want to have a serious surgery at such a young age but they told me it would be for the best. Their solution for my period was to keep me on birth control (Depo) which i was on straight for 11 years. I told my doctor a year ago i did not want to be on it anymore. For the first 4 months i was not bleeding at all then after that i started bleeding daily once again up until this day. Back in 2012 i told my doctor to run tests on me because i have a family history of thyroid problems and i wanted to be tested for it but my tsh came back normal so they told me i was fine but i had to beg my doctor to run further test because i felt i did have a thyroid problem but they all thought i was crazy making up symptoms and basically begging me to just take Xanax and that will help all my problems but i kept refusing. the reason i wanted more tests done on me is because i was having a hard time swallowing for a few months, my memory has been getting worse over time, i cant focus, bad anxiety and depression exc. i finally got my doctor to test my antibodies and i tested positive for hashimotos thyroiditis. That was back in 2012 no one called me or told me now 2 weeks ago i saw my new primary doctor he told me well what do you except you have an auto immune disease for life its never leaving. he barely told me anything else i had to look it up myself he doesn’t seem to know much about it. i have chronic fatigue its getting in the way of working i was just put on levothyroxine 25 mgs and he told me that’s all that needs to be done no further testing is necessary only to check in every once in a while to see if my dosage needs to be switched.i went vegan 2 1/2 years ago for health reasons (thanks to your videos) and my bleeding has lightened but I’m still bleeding daily. i have seen a gyno she told me its life just stay on birth control and that will solve my problems. My mom has about 4 auto immune diseases, is going blind, has hypo thyoid she had hyper until she got surgery on her thyroid then it switched to hypo, had similar period problem like me but hers would last 2-3 weeks straight and they couldn’t fix her problem and she was on levothyroxine as well but it did nothing for her period so they did a hysterectomy.i am not trying to go down the same path my mom is on and it seems like that’s where I’m headed. pleaseeeeeeeeeeeeeeee respond back. P.S sorry I’m all over the place in this message and sorry its so long!




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    1. Kasey Suarez, I feel for you, really. You must switch from your Delaware doctors and, perhaps, search for “natural” doctors. Unfortunately, America suffers from the idea that if a doctor says something, he/she is right. In my book, if whatever they think and do does not help me, I am out of there fast!. Just reading about anything -diets, medications, treatments, nutrition, etc. the key word is always “may”. “This *may* ease the pain”.
      “This *may* help with this or that”. In real terms, this means they do not know for a fact. Follow the suggestions from NutritionFacts. It has helped a lot of people and it might help you.




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    2. Hi I’m a health support volunteer with NF. I’m so sorry to hear about all you’re going through. We wish you all the best from all of us at nutritionfacts.org.

      You did say you went vegan awhile ago, but are you eating whole food plant based foods? All processed foods eliminated? Eating everything on Dr. Greger’s Daily Dozen? That is the first thing we would recommend.
      https://nutritionfacts.org/video/dr-gregers-daily-dozen-checklist-2/

      Dr. Greger has some videos on menstrual issues. I would follow these recommendations as they may have some of the same causes.
      https://nutritionfacts.org/video/how-to-treat-endometriosis-with-seaweed/
      https://nutritionfacts.org/video/dietary-treatment-for-painful-menstrual-periods/
      https://nutritionfacts.org/2014/04/17/treating-menstrual-pain-with-diet/

      I would also make sure you are following Dr. Greger’s recommendations for autoimmune disease and inflammation:
      https://nutritionfacts.org/topics/autoimmune-diseases/
      https://nutritionfacts.org/topics/inflammation/https://nutritionfacts.org/video/which-spices-fight-inflammation/

      Dr. McDougall, another proponent of plant based nutrition has also spoken on this subject:
      https://www.drmcdougall.com/health/education/health-science/common-health-problems/hormone-dependent-diseases-male-female/

      As your medical issues are a little complex, you may benefit from a consultation with a plant based nutrition physician. The Drs. at the True North Health Center and Dr. Michael Klaper do offer this. It may help to consult with them.
      https://doctorklaper.com/contact
      http://www.healthpromoting.com/no-cost-patient-screening

      All the best to you,
      NurseKelly




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