Anti-inflammatory diets can be effective in alleviating chronic pain syndromes.
The Best Diet for Fibromyalgia and Other Chronic Pain Relief
Below is an approximation of this video’s audio content. To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video.
Fibromyalgia is a common disorder whose cardinal manifestation is chronic, widespread pain. Well, not so common, affecting 2 to 4 percent of the population, though probably more like 2 percent, and especially women. For decades, some medical professionals dismissed fibromyalgia as all in people’s heads, but this outdated view has been refuted by more recent research characterizing it as a disorder of pain regulation and sensitization. Brain imaging studies have shown several perturbations of pain processing and regulation that amplify pain in people with the condition.
Twin studies have shown that about half of fibromyalgia is genetic, but the other half we can do something about. There are lots of drugs with lots of side effects to help with some of the symptoms, but what about lifestyle approaches? Engagement in regular physical activity is considered imperative for effective management of fibromyalgia.
A systematic review and meta-analysis of randomized clinical trials on the effectiveness of therapeutic exercise in fibromyalgia found that both aerobic and resistance exercises are effective ways of reducing pain and improving global well-being in people with fibromyalgia. Patients may worry, and perceive that exercise will worsen their pain and fatigue, and so you have to start slow and work your way up as tolerated, with the goal of eventually achieving daily 30 to 60 minutes of moderate intensity aerobic exercise in addition to muscle-strengthening exercises (1 to 3 sets of 8–11 exercises; 8–10 repetitions with a load of about 7 pounds, or 45 percent of the max you can lift). But what about dietary interventions in terms of dialing down the pain sensitivity?
Well, what causes it in the first place? Inflammation. During the inflammatory response, pain receptors are activated. And chronic inflammation can cause chronic activation, which may cause chronic pain due to this prolonged hypersensitization of pain pathways.
No wonder, then, that a pro-inflammatory diet was found to be associated with pain hypersensitivity in patients with fibromyalgia syndrome. Exactly which foods are pro-inflammatory and which foods are anti-inflammatory? Check out those twin videos: Foods That Cause Inflammation and Which Foods are Anti-Inflammatory? But broadly speaking, components of processed foods and animal products, such as saturated fat, trans fat, and cholesterol, were found to be pro-inflammatory, while constituents of whole plant foods, such as fiber and phytonutrients, were strongly anti-inflammatory.
The intake of dietary fiber found concentrated in only one place—whole plant foods—is fundamental to reducing not only the risk of abdominal pain, but also muscle and joint pain. We think it’s because of these short-chain fatty acids that our good gut bugs produce when we eat fiber. These short-chain fatty acids are important mediators of pain, fundamentally because they modulate inflammation. So, having lots of fiber-feeding bugs in your colon is like carrying around your own anti-inflammatory compound factory. But to cultivate them, you actually have to eat the foods that feed them.
In terms of phytonutrients, plant-derived polyphenols are widely acknowledged to also act as anti-inflammatory substances. Here are some foods packed with anti-pain pathway nutrients: berries, greens, citrus, nuts, spices like turmeric and ginger, edamame, and green tea. That’s why you can do a randomized, double-blind crossover trial showing that about three cups worth of strawberries a day can significantly improve pain and inflammation. If that’s what a single plant can do, what about a diet chock full of plant foods?
Put people on a strictly plant-based diet rich in fresh fruits and vegetables, whole grains, and various legumes, which are beans, split peas, chickpeas, and lentils, as well as nuts and seeds, and you can drop C-reactive protein levels (a leading blood marker of systemic inflammation) 33 percent in three weeks. But does that translate into less pain?
The answer is yes, when it comes to migraine headaches. Yes, when it comes to painful periods. A significant reduction in menstrual pain duration and pain intensity, in addition to premenstrual symptoms. In fact, even just a single plant, cinnamon, about a third of a teaspoon three times a day during your period can help, though it doesn’t work as well as ibuprofen. Ginger powder—ground ginger—on the other hand, has been found to be comparable to ibuprofen in relieving pain in women with painful cramps. You can learn more in my video on the topic: Benefits of Ginger for Menstrual Cramps.
Whole food plant-based diets also alleviate the symptoms of osteoarthritis. Several studies have shown improvements in rheumatoid arthritis symptoms with diets excluding animal products, though it may be just as much a function of increasing the quantity of healthy plant foods. But it’s not just because plant-based diets are so effective in causing weight loss. Even at the same weight, there’s an improvement in rheumatoid arthritis from more plant-based diets. And plant-based diets can also alleviate fibromyalgia symptoms.
This is the latest study, which enrolled anyone with chronic musculoskeletal pain, fibromyalgia or not. Yes, diets high in animal proteins and fats have been linked to chronic pain and inflammation, while plant-based diets produce anti-inflammatory responses. Did it actually work when put to the test for pain? Yes. Consumption of a plant-based diet produced positive improvements in chronic pain and function. How much? A minimally clinically important difference in chronic musculoskeletal pain is 1 point on the Numeric Pain Rating Scale, which is just a scale from 1 to 10 on how much pain you’re feeling. On the plant-based diet, perceived pain decreased an average of 3 points on a 10-point scale, from an average of 5 or 6 out of 10 down to 2. Now, unlike most prior studies, there was no control group. But what’s the downside of giving healthier eating a try? In fact, those with chronic pain are more likely to be overweight, and have nutrition-related maladies such as high blood pressure, diabetes, and heart disease––all of which can be prevented, arrested, and in some cases even reversed with a healthy enough plant-based diet. So, any pain benefit is just icing on the cake of health.
Uh, scratch that. How about the dollop of guacamole on your bean burrito.
Please consider volunteering to help out on the site.
- Bair MJ, Krebs EE. Fibromyalgia. Ann Intern Med. 2020;172(5):ITC33-ITC48.
- Heidari F, Afshari M, Moosazadeh M. Prevalence of fibromyalgia in general population and patients, a systematic review and meta-analysis. Rheumatol Int. 2017;37(9):1527-1539.
- Sosa-Reina MD, Nunez-Nagy S, Gallego-Izquierdo T, Pecos-Martín D, Monserrat J, Álvarez-Mon M. Effectiveness of Therapeutic Exercise in Fibromyalgia Syndrome: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Biomed Res Int. 2017;2017:2356346.
- Elma Ö, Yilmaz ST, Deliens T, et al. Do Nutritional Factors Interact with Chronic Musculoskeletal Pain? A Systematic Review. J Clin Med. 2020;9(3):702.
- Correa-Rodríguez M, Casas-Barragán A, González-Jiménez E, Schmidt-RioValle J, Molina F, Aguilar-Ferrándiz ME. Dietary Inflammatory Index Scores Are Associated with Pressure Pain Hypersensitivity in Women with Fibromyalgia. Pain Med. 2020;21(3):586-594.
- Bjørklund G, Aaseth J, Doşa MD, et al. Does diet play a role in reducing nociception related to inflammation and chronic pain?. Nutrition. 2019;66:153-165.
- Schell J, Scofield RH, Barrett JR, et al. Strawberries Improve Pain and Inflammation in Obese Adults with Radiographic Evidence of Knee Osteoarthritis. Nutrients. 2017;9(9):949.
- Towery P, Guffey JS, Doerflein C, Stroup K, Saucedo S, Taylor J. Chronic musculoskeletal pain and function improve with a plant-based diet. Complement Ther Med. 2018;40:64-69.
- Sutliffe JT, Wilson LD, de Heer HD, Foster RL, Carnot MJ. C-reactive protein response to a vegan lifestyle intervention. Complement Ther Med. 2015;23(1):32-37.
- Bunner AE, Agarwal U, Gonzales JF, Valente F, Barnard ND. Nutrition intervention for migraine: a randomized crossover trial. J Headache Pain. 2014;15(1):69.
- Barnard ND, Scialli AR, Hurlock D, Bertron P. Diet and sex-hormone binding globulin, dysmenorrhea, and premenstrual symptoms. Obstet Gynecol. 2000;95(2):245-250.
- Jahangirifar M, Taebi M, Dolatian M. The effect of Cinnamon on primary dysmenorrhea: A randomized, double-blind clinical trial. Complement Ther Clin Pract. 2018;33:56-60.
- Jaafarpour M, Hatefi M, Khani A, Khajavikhan J. Comparative effect of cinnamon and Ibuprofen for treatment of primary dysmenorrhea: a randomized double-blind clinical trial. J Clin Diagn Res. 2015;9(4):QC04-QC7.
- Ozgoli G, Goli M, Moattar F. Comparison of effects of ginger, mefenamic acid, and ibuprofen on pain in women with primary dysmenorrhea. J Altern Complement Med. 2009;15(2):129-132.
- Clinton CM, O'Brien S, Law J, Renier CM, Wendt MR. Whole-foods, plant-based diet alleviates the symptoms of osteoarthritis. Arthritis. 2015;2015:708152.
- Alwarith J, Kahleova H, Rembert E, et al. Nutrition Interventions in Rheumatoid Arthritis: The Potential Use of Plant-Based Diets. A Review. Front Nutr. 2019;6:141.
- Sköldstam L, Brudin L, Hagfors L, Johansson G. Weight reduction is not a major reason for improvement in rheumatoid arthritis from lacto-vegetarian, vegan or Mediterranean diets. Nutr J. 2005;4:15.
- Kaartinen K, Lammi K, Hypen M, Nenonen M, Hanninen O, Rauma AL. Vegan diet alleviates fibromyalgia symptoms. Scand J Rheumatol. 2000;29(5):308-313.
- Brain K, Burrows TL, Rollo ME, et al. A systematic review and meta-analysis of nutrition interventions for chronic noncancer pain. J Hum Nutr Diet. 2019;32(2):198-225.
Motion graphics by Avo Media
- animal products
- animal protein
- anti-inflammatory
- arthritis
- berries
- blood pressure
- body weight
- C-reactive protein
- cardiovascular disease
- chickpeas
- cholesterol
- cinnamon
- citrus
- diabetes
- edamame
- exercise
- fatigue
- fiber
- fibromyalgia
- fruit
- ginger
- grains
- green tea
- greens
- gut flora
- headaches
- heart disease
- high blood pressure
- hypertension
- Ibuprofen
- inflammation
- lentils
- menstruation
- microbiome
- migraine headaches
- nuts
- osteoarthritis
- pain
- phytonutrients
- Plant-Based Diets
- processed foods
- rheumatoid arthritis
- saturated fat
- seeds
- short-chain fatty acids
- soy
- spices
- split peas
- strawberries
- tea
- trans fat
- turmeric
- vegans
- vegetables
- vegetarians
- weight loss
- women's health
Below is an approximation of this video’s audio content. To see any graphs, charts, graphics, images, and quotes to which Dr. Greger may be referring, watch the above video.
Fibromyalgia is a common disorder whose cardinal manifestation is chronic, widespread pain. Well, not so common, affecting 2 to 4 percent of the population, though probably more like 2 percent, and especially women. For decades, some medical professionals dismissed fibromyalgia as all in people’s heads, but this outdated view has been refuted by more recent research characterizing it as a disorder of pain regulation and sensitization. Brain imaging studies have shown several perturbations of pain processing and regulation that amplify pain in people with the condition.
Twin studies have shown that about half of fibromyalgia is genetic, but the other half we can do something about. There are lots of drugs with lots of side effects to help with some of the symptoms, but what about lifestyle approaches? Engagement in regular physical activity is considered imperative for effective management of fibromyalgia.
A systematic review and meta-analysis of randomized clinical trials on the effectiveness of therapeutic exercise in fibromyalgia found that both aerobic and resistance exercises are effective ways of reducing pain and improving global well-being in people with fibromyalgia. Patients may worry, and perceive that exercise will worsen their pain and fatigue, and so you have to start slow and work your way up as tolerated, with the goal of eventually achieving daily 30 to 60 minutes of moderate intensity aerobic exercise in addition to muscle-strengthening exercises (1 to 3 sets of 8–11 exercises; 8–10 repetitions with a load of about 7 pounds, or 45 percent of the max you can lift). But what about dietary interventions in terms of dialing down the pain sensitivity?
Well, what causes it in the first place? Inflammation. During the inflammatory response, pain receptors are activated. And chronic inflammation can cause chronic activation, which may cause chronic pain due to this prolonged hypersensitization of pain pathways.
No wonder, then, that a pro-inflammatory diet was found to be associated with pain hypersensitivity in patients with fibromyalgia syndrome. Exactly which foods are pro-inflammatory and which foods are anti-inflammatory? Check out those twin videos: Foods That Cause Inflammation and Which Foods are Anti-Inflammatory? But broadly speaking, components of processed foods and animal products, such as saturated fat, trans fat, and cholesterol, were found to be pro-inflammatory, while constituents of whole plant foods, such as fiber and phytonutrients, were strongly anti-inflammatory.
The intake of dietary fiber found concentrated in only one place—whole plant foods—is fundamental to reducing not only the risk of abdominal pain, but also muscle and joint pain. We think it’s because of these short-chain fatty acids that our good gut bugs produce when we eat fiber. These short-chain fatty acids are important mediators of pain, fundamentally because they modulate inflammation. So, having lots of fiber-feeding bugs in your colon is like carrying around your own anti-inflammatory compound factory. But to cultivate them, you actually have to eat the foods that feed them.
In terms of phytonutrients, plant-derived polyphenols are widely acknowledged to also act as anti-inflammatory substances. Here are some foods packed with anti-pain pathway nutrients: berries, greens, citrus, nuts, spices like turmeric and ginger, edamame, and green tea. That’s why you can do a randomized, double-blind crossover trial showing that about three cups worth of strawberries a day can significantly improve pain and inflammation. If that’s what a single plant can do, what about a diet chock full of plant foods?
Put people on a strictly plant-based diet rich in fresh fruits and vegetables, whole grains, and various legumes, which are beans, split peas, chickpeas, and lentils, as well as nuts and seeds, and you can drop C-reactive protein levels (a leading blood marker of systemic inflammation) 33 percent in three weeks. But does that translate into less pain?
The answer is yes, when it comes to migraine headaches. Yes, when it comes to painful periods. A significant reduction in menstrual pain duration and pain intensity, in addition to premenstrual symptoms. In fact, even just a single plant, cinnamon, about a third of a teaspoon three times a day during your period can help, though it doesn’t work as well as ibuprofen. Ginger powder—ground ginger—on the other hand, has been found to be comparable to ibuprofen in relieving pain in women with painful cramps. You can learn more in my video on the topic: Benefits of Ginger for Menstrual Cramps.
Whole food plant-based diets also alleviate the symptoms of osteoarthritis. Several studies have shown improvements in rheumatoid arthritis symptoms with diets excluding animal products, though it may be just as much a function of increasing the quantity of healthy plant foods. But it’s not just because plant-based diets are so effective in causing weight loss. Even at the same weight, there’s an improvement in rheumatoid arthritis from more plant-based diets. And plant-based diets can also alleviate fibromyalgia symptoms.
This is the latest study, which enrolled anyone with chronic musculoskeletal pain, fibromyalgia or not. Yes, diets high in animal proteins and fats have been linked to chronic pain and inflammation, while plant-based diets produce anti-inflammatory responses. Did it actually work when put to the test for pain? Yes. Consumption of a plant-based diet produced positive improvements in chronic pain and function. How much? A minimally clinically important difference in chronic musculoskeletal pain is 1 point on the Numeric Pain Rating Scale, which is just a scale from 1 to 10 on how much pain you’re feeling. On the plant-based diet, perceived pain decreased an average of 3 points on a 10-point scale, from an average of 5 or 6 out of 10 down to 2. Now, unlike most prior studies, there was no control group. But what’s the downside of giving healthier eating a try? In fact, those with chronic pain are more likely to be overweight, and have nutrition-related maladies such as high blood pressure, diabetes, and heart disease––all of which can be prevented, arrested, and in some cases even reversed with a healthy enough plant-based diet. So, any pain benefit is just icing on the cake of health.
Uh, scratch that. How about the dollop of guacamole on your bean burrito.
Please consider volunteering to help out on the site.
- Bair MJ, Krebs EE. Fibromyalgia. Ann Intern Med. 2020;172(5):ITC33-ITC48.
- Heidari F, Afshari M, Moosazadeh M. Prevalence of fibromyalgia in general population and patients, a systematic review and meta-analysis. Rheumatol Int. 2017;37(9):1527-1539.
- Sosa-Reina MD, Nunez-Nagy S, Gallego-Izquierdo T, Pecos-Martín D, Monserrat J, Álvarez-Mon M. Effectiveness of Therapeutic Exercise in Fibromyalgia Syndrome: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Biomed Res Int. 2017;2017:2356346.
- Elma Ö, Yilmaz ST, Deliens T, et al. Do Nutritional Factors Interact with Chronic Musculoskeletal Pain? A Systematic Review. J Clin Med. 2020;9(3):702.
- Correa-Rodríguez M, Casas-Barragán A, González-Jiménez E, Schmidt-RioValle J, Molina F, Aguilar-Ferrándiz ME. Dietary Inflammatory Index Scores Are Associated with Pressure Pain Hypersensitivity in Women with Fibromyalgia. Pain Med. 2020;21(3):586-594.
- Bjørklund G, Aaseth J, Doşa MD, et al. Does diet play a role in reducing nociception related to inflammation and chronic pain?. Nutrition. 2019;66:153-165.
- Schell J, Scofield RH, Barrett JR, et al. Strawberries Improve Pain and Inflammation in Obese Adults with Radiographic Evidence of Knee Osteoarthritis. Nutrients. 2017;9(9):949.
- Towery P, Guffey JS, Doerflein C, Stroup K, Saucedo S, Taylor J. Chronic musculoskeletal pain and function improve with a plant-based diet. Complement Ther Med. 2018;40:64-69.
- Sutliffe JT, Wilson LD, de Heer HD, Foster RL, Carnot MJ. C-reactive protein response to a vegan lifestyle intervention. Complement Ther Med. 2015;23(1):32-37.
- Bunner AE, Agarwal U, Gonzales JF, Valente F, Barnard ND. Nutrition intervention for migraine: a randomized crossover trial. J Headache Pain. 2014;15(1):69.
- Barnard ND, Scialli AR, Hurlock D, Bertron P. Diet and sex-hormone binding globulin, dysmenorrhea, and premenstrual symptoms. Obstet Gynecol. 2000;95(2):245-250.
- Jahangirifar M, Taebi M, Dolatian M. The effect of Cinnamon on primary dysmenorrhea: A randomized, double-blind clinical trial. Complement Ther Clin Pract. 2018;33:56-60.
- Jaafarpour M, Hatefi M, Khani A, Khajavikhan J. Comparative effect of cinnamon and Ibuprofen for treatment of primary dysmenorrhea: a randomized double-blind clinical trial. J Clin Diagn Res. 2015;9(4):QC04-QC7.
- Ozgoli G, Goli M, Moattar F. Comparison of effects of ginger, mefenamic acid, and ibuprofen on pain in women with primary dysmenorrhea. J Altern Complement Med. 2009;15(2):129-132.
- Clinton CM, O'Brien S, Law J, Renier CM, Wendt MR. Whole-foods, plant-based diet alleviates the symptoms of osteoarthritis. Arthritis. 2015;2015:708152.
- Alwarith J, Kahleova H, Rembert E, et al. Nutrition Interventions in Rheumatoid Arthritis: The Potential Use of Plant-Based Diets. A Review. Front Nutr. 2019;6:141.
- Sköldstam L, Brudin L, Hagfors L, Johansson G. Weight reduction is not a major reason for improvement in rheumatoid arthritis from lacto-vegetarian, vegan or Mediterranean diets. Nutr J. 2005;4:15.
- Kaartinen K, Lammi K, Hypen M, Nenonen M, Hanninen O, Rauma AL. Vegan diet alleviates fibromyalgia symptoms. Scand J Rheumatol. 2000;29(5):308-313.
- Brain K, Burrows TL, Rollo ME, et al. A systematic review and meta-analysis of nutrition interventions for chronic noncancer pain. J Hum Nutr Diet. 2019;32(2):198-225.
Motion graphics by Avo Media
- animal products
- animal protein
- anti-inflammatory
- arthritis
- berries
- blood pressure
- body weight
- C-reactive protein
- cardiovascular disease
- chickpeas
- cholesterol
- cinnamon
- citrus
- diabetes
- edamame
- exercise
- fatigue
- fiber
- fibromyalgia
- fruit
- ginger
- grains
- green tea
- greens
- gut flora
- headaches
- heart disease
- high blood pressure
- hypertension
- Ibuprofen
- inflammation
- lentils
- menstruation
- microbiome
- migraine headaches
- nuts
- osteoarthritis
- pain
- phytonutrients
- Plant-Based Diets
- processed foods
- rheumatoid arthritis
- saturated fat
- seeds
- short-chain fatty acids
- soy
- spices
- split peas
- strawberries
- tea
- trans fat
- turmeric
- vegans
- vegetables
- vegetarians
- weight loss
- women's health
Republishing "The Best Diet for Fibromyalgia and Other Chronic Pain Relief"
You may republish this material online or in print under our Creative Commons licence. You must attribute the article to NutritionFacts.org with a link back to our website in your republication.
If any changes are made to the original text or video, you must indicate, reasonably, what has changed about the article or video.
You may not use our material for commercial purposes.
You may not apply legal terms or technological measures that restrict others from doing anything permitted here.
If you have any questions, please Contact Us
The Best Diet for Fibromyalgia and Other Chronic Pain Relief
LicenseCreative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
Content URLDoctor's Note
The duo of inflammation videos I mentioned are Foods That Cause Inflammation and Which Foods Are Anti-Inflammatory?. And, the video on cramps is Benefits of Ginger for Menstrual Cramps.
I have a few other videos on fibromyalgia. Check out:
- Fibromyalgia vs. Vegetarian and Raw Vegan Diets
- Aspartame-Induced Fibromyalgia
- How to Strengthen the Mind-Body Connection
- The Best Supplement for Fibromyalgia
If you haven't yet, you can subscribe to our free newsletter. With your subscription, you'll also get notifications for just-released blogs and videos. Check out our information page about our translated resources.